DNA hydrogels and nanogels for diagnostics, therapeutics, and theragnostics of various cancers

Abstract

As an efficient class of hydrogel-based therapeutic drug delivery systems, deoxyribonucleic acid (DNA) hydrogels (particularly DNA nanogels) have attracted massive attention in recent five years. The main contributor to this...

1H-NMR studies on the volume phase transition of DNA-modified pNipmam microgels

“…42 A VPTT around the body temperature combined with the high specific surface of μG and with that a high loading capacity makes them promising candidates for these and even more biomedical applications. 43,44…”

Intelligent DNA-Based Hydrogels for Bioanalysis and Therapeutics

“…These are things that traditional nanomaterials cannot achieve in terms of treatment. 150 DNA-based hydrogels can be used well in drug delivery systems and have been used in the drug treatment of a variety of diseases, including tumors, immune diseases, wound healing, and analgesia. 151,152 However, there are still many shortcomings or problems in the development of DNA-based hydrogels that need to be further studied and explored: (1) The cost of large-scale preparation of DNA-based hydrogel is expensive, and the synthesis purity is not up to standard.…”

“…Locally injected DNA-based hydrogels are more permeable and stimuli-responsive. These are things that traditional nanomaterials cannot achieve in terms of treatment . DNA-based hydrogels can be used well in drug delivery systems and have been used in the drug treatment of a variety of diseases, including tumors, immune diseases, wound healing, and analgesia. , …”

Bonding states of gold/silver plasmonic nanostructures and sulfur-containing active biological ingredients in biomedical applications: a review

“…5,6 An array of modern technologies have been used to search for new drug delivery processes. 7–10 Au and Ag NPs have been surface-functionalized with various capping and stabilizing agents, such as chelating agents consisting of disulfides, carboxylates, amines, hydroxyl compounds, and surfactants based on phosphate. 11 It is desirable to control, characterize, and functionalize Au and Ag NPs protected by thiols in light of the robust S/Au bonds and their effortless control, identification, and functionalization.…”