DNA damage and 2′-deoxyguanosine oxidation induced by S(IV) autoxidation catalyzed by copper(II) tetraglycine complexes: Synergistic effect of a second metal ion

A novel binuclear palladium complex with benzothiazole-2-thiolate: Synthesis, crystal structure and interaction with DNA

“…The ability of complexes to perform DNA cleavage is generally monitored by agarose gel electrophoresis, and the pUC19 plasmid DNA, pBR322 plasmid DNA and pUC18 plasmid DNA are usually involved [39][40][41]. Agarose gel electrophoresis using pUC19 plasmid DNA in the present of the title complex was carried out and was shown as Fig.…”

Synthesis, crystal structure, and interaction with DNA of a novel coordination polymer: {[Cd(Pmal)(Bipy)] · 4H2O} n

“…The cleavage reaction on plasmid DNA can be monitored by agarose gel electrophoresis. The effi ciency of cleavage of these molecules was probed using agarose gel electrophoresis [23][24][25]. When circular plasmid DNA is subjected to electrophoresis, rela tively fast migration will be observed for the intact supercoil form (Form I).…”

In vitro and in silico analysis of the effect of fluconazole, an antifungal drug, on DNA

“…The migration of the linear form through agarose gel is slower than the supercoiled form and faster than the open circle form. 22 Concentrations of fluconazole in human plasma have been reported as 26.9 mg/ml (87.8 µM). 23 Human cells are exposed to ascorbate concentrations in the range of 10 to 70 µM.…”