Diverse synthesis of functionalized hydroquinoline derivatives from α-aryl vinylsulfonium salts

Abstract

Vinylsulfonium salt chemistry is becoming increasingly attractive in the synthesis of heterocyclic motifs for its high efficiency and versatility. In this article, we achieve diverse transformations of α-aryl vinylsulfonium salts...

Solvent-involved synthesis of pyrrolidin-5-one-2-carboxamides via a sequential Ugi/olefination reaction

“…1a). 4 The research groups of Aggarwal, 5 Tang, 6 Xiao, 7 Huang 8 and others 9 have disclosed many elegant reactions of sulfur ylides used to generate novel compounds. This traditional reactivity pattern utilizes sulfur ylides as intermediates to form various cyclic molecules through cycloaddition reactions.…”

Facile synthesis of 2-vinylindolines via a phosphine-mediated α-umpolung/Wittig olefination/cyclization cascade process

“…On the other hand, o -aminobenzaldehydes were employed to forge a variety of benzo-heterocycles, including indolines, dihydroquinolines, quinolines, and benzoazepines. 11 Meanwhile, o -aminobenzaldehydes can also be used as substrates in phosphine-catalyzed reactions. 11 b – d In 2018, Kwon and co-workers developed a phosphine-catalyzed γ-umpolung addition–Wittig olefination of o -aminobenzaldehydes with allenoates to produce 1,2-dihydroquinolines.…”