Diurnal Tonography in Normal and Glaucomatous Eyes*

Newell, Frank W.; Krill, Alex E.

doi:10.1016/0002-9394(65)93016-3

Cited by 44 publications

(34 citation statements)

References 30 publications

(8 reference statements)

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“…20,21 Others concluded that any variation with the resistance was not in phase with the diurnal variation in tension. 22 while others again have found that the resistance was unchanged throughout the day. 18,23 Few investigators.…”

Section: Resultsmentioning

confidence: 90%

“…35 Although the IOP may be raised or lowered temporarily by changes in systemic arterial or venous pressure, it is unlikely that either factor is of great significance in diurnal tension fluctuations. 22 Usually, although not continuously, healthy subjects yield the highest IOP values at the beginning of the day, upon waking up, slowly decreasing during the day until bedtime and gradually increasing again during the night. Differences between maximum and minimum values may amount to 8 mmHg.…”

Section: Resultsmentioning

confidence: 98%

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Physiological Variable Affectin G Intra Ocu Lar Pressure: Diurnal Variations

H¹

2015

jemds

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BACKGROUND:The existence of a diurnal variation in the Intra ocular Pressure (IOP) of both normal and glaucomatous eyes is well documented. However, the magnitude and pattern of that variation remains in conjecture. AIM: To study the diurnal fluctuation of the IOP in the normal subjects. MATERIALS AND METHODS: The study group consisted of 92 volunteers, visually normal as subjects, 50 boys and 42 girls in the age group of 18 to 20 years. Independent measurements of the IOP of each eye were obtained during the day with the subject in the upright position. The first measurement was undertaken between 8-9AM, the second between 12 Noon-1PM and the final reading between 5-6PM. The subjects carried normal routine activity during the period of measurement. Keelar Pulsair air impulse tonometer was used in all the subjects for IOP measurement. IOP was measured in the department of Ophthalmology, Teaching Hospital. STATISTICAL ANALYSIS: were done using Paired 't' test. RESULTS: The mean IOP of all the subjects decreased by 2.304 mmHg during the day. The change was statistically significant (<0.001). Mean IOP decreased by 2.977mmHg during the day in 83.69% of the subjects, all showing peak pressures in the morning. In a small proportion of subjects (10.86%) the mean increased by 1.75mm Hg which was not statistically significant. In 5.43% of the subjects the IOP remained the same during the day. The present study did not find any association between age, sex and the IOP parameters examined (Time of peak, trough and diurnal fluctuation). CONCLUSION: IOP decreased during the in a large number of subjects (83.69%). The peak IOP was before noon. The diurnal IOP variation is quite minimal averaging 3-4 mm Hg but a single measurement taken during the late afternoon or evening may miss IOP peak. There is no method to continually measure IOP. Even a large number of pressure measurements dispersed through a 24-hour period may miss the peak pressure for that day. Thus, it is obvious that any choice of measurement is arbitrary. Many factors are responsible for daily fluctuations in IOP. Some of these factors operate at the level of the eye.

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Section: Resultsmentioning

confidence: 90%

Section: Resultsmentioning

confidence: 98%

Physiological Variable Affectin G Intra Ocu Lar Pressure: Diurnal Variations

H¹

2015

jemds

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“…Patients with glaucoma have much swings of intra ocular pressure that can reach 30mmHg or even 50mmHg in rare cases 7 .Most of the diurnal pressure variation is caused by fluctuations in the rate of aqueous humor formation. The rate of aqueous humor formation falls to low levels during sleep and increases during the day, most likely in response to circulating catecholamines 8,9 .…”

Section: Discussionmentioning

confidence: 99%

Diurnal Variation in the Cardiovascular Indices and Intraocular Pressure

Patil¹,

Doddamani

Farooqui³

2012

Int J of Biomed & Adv Res

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Introduction: Intra ocular pressure is an essential entity in maintaining the structural and functional integrity of eye ball. It varies in regular cycle in the normal eye for 24hour. In the present study, the diurnal variation of Heart rate, intra ocular pressure, systolic, diastolic, pulse and mean arterial pressures from 6AM to 6PM with every 2 hour interval was investigated. Methodology: The present study included 100 normal male healthy subjects from the Gulbarga city, recruited after their informed and written consent. Intra ocular pressure, Heart rate, Blood pressure, Temperature, Urine output and respiratory rate per minute was investigated in all the subjects. Diurnal variation of Intra ocular pressure, Blood pressure, heart rate was measured at every 2hrs from 6 AM to 6 PM. Result: The diurnal variation of Intra Ocular Pressure was significantly high (p<0.05). The diurnal variation of Heart Rate and Blood Pressure showed variations from 6AM to 6PM within physiological limits. Discussion: The diurnal variation of Intra Ocular Pressure, Heart Rate and Blood Pressure in early morning and at evening might be due to the combined homeostatic mechanism of autonomic nervous system and glucocorticoid release. Conclusion: Hence intra ocular pressure fluctuation more than 30 mmHg during diurnal variation water has diagnostic value towards development of latent Glaucoma.

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“…However, measurement of IOP has poor diagnostic precision. There are several contributory factors to this shortcoming: the proportion of patients with normal tension glaucoma, 26,27 the dependence of the measurement on central corneal thickness 28 and the diurnal variation in IOP 29 (which is enhanced in some glaucoma patients 30 ).…”

Section: Epidemiologymentioning

confidence: 99%

The effectiveness of the Heidelberg Retina Tomograph and laser diagnostic glaucoma scanning system (GDx) in detecting and monitoring glaucoma

Kwartz

Henson²,

Harper³

et al. 2005

Health Technol Assess

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Diurnal Tonography in Normal and Glaucomatous Eyes*

Cited by 44 publications

References 30 publications

Physiological Variable Affectin G Intra Ocu Lar Pressure: Diurnal Variations

Physiological Variable Affectin G Intra Ocu Lar Pressure: Diurnal Variations

Diurnal Variation in the Cardiovascular Indices and Intraocular Pressure

The effectiveness of the Heidelberg Retina Tomograph and laser diagnostic glaucoma scanning system (GDx) in detecting and monitoring glaucoma

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