Diterpenes and other constituents from Pteronia species

Zdero, Christa; Jakupovic, J.; Bohlmann, Ferdinand

doi:10.1016/0031-9422(90)85434-h

Cited by 35 publications

(34 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This compound has not been found in any other species of the genus Hedyosmum, and has been reported previously only in Pteronia camphorata L. extracts. 16 Enzymatic reactions are commonly characterized by a high degree of stereospecifity. Thus, in order to obtain accurate information with respect to chirality, analytical procedures of the highest selectivity, which employ chiral separation without racemization, must be utilized.…”

Section: Resultsmentioning

confidence: 99%

Composition of the essential oils from leaves of two Hedyosmum spp. from Bolivia

Lorenzo¹,

Loayza²,

Dellacassa³

2002

Flavour & Fragrance J

View full text Add to dashboard Cite

Essential oils obtained by hydrodistillation from aerial parts of Hedyosmum angustifolium (Ruiz & Pavón) Solms-Laubach and H. scabrum (Ruiz & Pavón) Solms-Laubach from Bolivia were analysed by GC-FID and GC-MS. Monoterpene hydrocarbons, especially˛-andˇ-pinene, and oxygen containing monoterpenes, mainly 1,8-cineole and linalool, were the major constituents found in the oils of H. angustifolium. The oil of H. scabrum was mainly made up of monoterpenes, in particular υ-3-carene, the sesquiterpene hydrocarbons˛-gurjunene and germacrene D, and 3 0 , 4 0 -dimethoxypropiophenone. For both oils, the enantiomeric distribution of -pinene, sabinene,ˇ-pinene, limonene, linalool, terpinen-4-ol and˛-terpineol was studied by multidimensional HRGC-HRGC. The main difference between the oils corresponded to the reverse enantiomeric distribution found for linalool, indicating a clear index of different metabolic response in each species.

show abstract

Section: Resultsmentioning

confidence: 99%

Composition of the essential oils from leaves of two Hedyosmum spp. from Bolivia

Lorenzo¹,

Loayza²,

Dellacassa³

2002

Flavour & Fragrance J

View full text Add to dashboard Cite

show abstract

“…In literature the use of Schkuhria pinnata as an anti-diabetic agent is numerous but no literature could be found on the chemical analysis and testing for it's hypoglycaemic activity. Zdero et al (1990) isolated some neryl geraniol derivates, clerodane and three diterpenes form Pteronia divaricata. The triterpenes Betulin and lupeol were isolated from Euclea natalensis by Weigenand et al (2004) and Khan and Rwekika (1992).…”

Section: Discussionmentioning

confidence: 99%

Hypoglycaemic activity of four plant extracts traditionally used in South Africa for diabetes

Deutschländer

Venter

Roux

et al. 2009

Journal of Ethnopharmacology

View full text Add to dashboard Cite

a b s t r a c tAim: To validate plant species for hypoglycaemic activity. Materials and methods: Four plants were investigated for hypoglycaemic activity by evaluating inhibiting effects on carbohydrate-hydrolising enzymes: ␣-glucosidase and ␣-amylase. Acetone plant extracts were screened against C2C12 myocytes, 3T3-L1 preadipocytes and Chang liver cells by measuring glucose uptake. Cytotoxicity was done in preadipocytes and hepatocytes. Results: Extract of Euclea undulata rootbark exhibited highest activity, displaying a glucose uptake of 162.2% by Chang liver cells at 50 g/ml. An inhibition concentration of 50% for Euclea undulata was found to be 49.95 g/ml for ␣-glucosidase and 2.8 g/ml for ␣-amylase. No cytotoxicity was recorded for Euclea undulata, while Schkuhria pinnata and Elaeodendron transvaalense exhibited cytotoxicity at 12.5 g/ml. ␣-Glucosidase and ␣-amylase assays showed inhibitory activity on enzymes for three plant extracts. Conclusion: Euclea undulata, Schkuhria pinnata and Elaeodendron transvaalense showed in vitro hypoglycaemic activity. Schkuhria pinnata and Elaeodendron transvaalense indicated cytotoxicity on 3T3-L1 preadipocytes and Chang liver cells. Euclea undulata, Pteronia divaricata and Elaeodendron transvaalense inhibited ␣-glucosidase and ␣-amylase enzymes. Ethnopharmacological relevance: Screening of plant extracts scientifically validated traditional use of Euclea undulata for treatment of diabetes. Cytotoxicity results revealed that acetone extracts of Schkuhria pinnata and Elaeodendron transvaalense are toxic and raise concern for chronic use.

show abstract

“…Each fraction was repeatedly separated by a combination of different chromatographies to give two new compounds, 1 and 2, together with seven known compounds, 2,2-dimethyl-6-vinylchromene (3), 7) acetophenone (4), 2-prenyl-4-vinylphenol (5), 8) 3,4-dimethoxy-styrene (6), 9) 3,4-dimethoxy-allylbenzene (7), 9) 4-hydroxy-3,5-diprenylbenzaldehyde (8), 10) and (Ϫ)-spathulenol (9).…”

Section: Resultsmentioning

confidence: 99%

Isolation and Structures of Two New Compounds from the Essential Oil of Brazilian Propolis.

et al. 2001

View full text Add to dashboard Cite

show abstract

Diterpenes and other constituents from Pteronia species

Cited by 35 publications

References 15 publications

Composition of the essential oils from leaves of two Hedyosmum spp. from Bolivia

Composition of the essential oils from leaves of two Hedyosmum spp. from Bolivia

Hypoglycaemic activity of four plant extracts traditionally used in South Africa for diabetes

Isolation and Structures of Two New Compounds from the Essential Oil of Brazilian Propolis.

Contact Info

Product

Resources

About