Distribution of toxic elements in teeth treated with amalgam using μ-energy dispersive X-ray fluorescence

Benchtop X-ray fluorescence imaging as a tool to study gold nanoparticle penetration in 3D cancer spheroids

“…In the last decade there has been a rise in the use of XRF facilities to investigate toxic metals concentration distribution in biological tissues such as plants [15][16][17] and animals, [18][19][20] among which are human tissues. [21][22][23] Due to the difficulty in access to large facilities such as synchrotrons and free electron lasers, researchers started moving towards the use of bench-top micro-XRF spectrometers to perform hyperspectral images of elemental distribution in tissues previously exposed to contaminants. 24 There is however a scarcity of papers in the literature regarding the use of bench-top m-XRF imaging to study the distribution of nanoparticles in human tissues, especially tumours.…”