Distribution of the Resident Oral Bacterial Populations in Different Strains of Mice

Gadbois, T.; Marcotte, Harold; Rodrigue, L.; Coulombe, C.; Goyette, Nathalie; Lavoie, Marie

doi:10.3402/mehd.v6i5.8143

Cited by 8 publications

(15 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As the results are presented as the proportion of the total cultivable bacterial biota, they could be viewed, not as an increase of the second most predominent species that happened to be present (staphylococci or streptococci) but rather as a decrease in the lactobacilli population. We have previously observed that another stress, transportation [6], results in a decrease in the oral lactobacilli population. Similar results were also observed by others concerning the population of lactobacilli found in the fecal biota [30,32].…”

Section: Discussionmentioning

confidence: 99%

Evolution of resident oral bacterial biota in BALB/c mice during pregnancy and lactation

Coulombe¹,

Lavoie²

1995

Microb Ecol

Self Cite

View full text Add to dashboard Cite

To assess the influence of pregnancy and lactation on the oral microbial ecology of BALB/c mice, we followed the distribution of the predominant oral bacteria of four groups of these mice during these two periods. Compared with nonpregnant control female mice of the same age maintained under the same conditions, the distribution of the resident oral bacterial species differed significantly only during the lactation period (8-16 days after parturition). This difference could possibly be attributed to hormonal influences and/or grooming habits.

show abstract

Section: Discussionmentioning

confidence: 99%

Evolution of resident oral bacterial biota in BALB/c mice during pregnancy and lactation

Coulombe¹,

Lavoie²

1995

Microb Ecol

Self Cite

View full text Add to dashboard Cite

show abstract

“…It has been observed that the proportion of Lactobacillus sp. decreases in stressed mice (6,33,35). Nude mice are more susceptible to temperature variations.…”

Section: S Oralismentioning

confidence: 99%

Comparison of the indigenous oral microbiota and immunoglobulin responses of athymic (nu/nu) and euthymic (nu/+) mice

Marcotte

Lavoie

1997

Oral Microbiology and Immunology

Self Cite

View full text Add to dashboard Cite

The role of the immune system in the homeostasis of indigenous oral bacterial populations is poorly understood. In this study, we compared the evolution of the indigenous oral microbiota of specific pathogen-free athymic nude (nu/nu) BALB/c mice with that of their corresponding phenotypically normal (nu/-) littermates. We also evaluated corresponding salivary and serum antibody activities (IgA and IgG) against the predominant indigenous oral bacteria. The bacterial species recovered from the two mouse strains were Lactobacillus murinus, Enterococcus faecalis, Streptococcus oralis and Staphylococcus epidermidis. From 27 days of age, nu/+ and nu/nu mice had significantly different proportions of oral bacterial populations. When the microbiota stabilized (at 40 days of age), the total cultivable microbiota of nu/+ mice was dominated by L. murinus (65-85%), while that of nu/nu mice was dominated by E. faecalis (40-60%). The precise factors that alter the oral resident microbiota in nu/nu mice are unknown. We found that total salivary IgA levels were significantly lower in nu/nu mice, but no association were observed between the level of salivary IgA antibody against indigenous bacteria and the proportion of these indigenous bacteria in the oral microbiota. The change in the microbiota of nude mice may have been caused by other factors such as defects in other immune functions or cold stress.

show abstract

“…While studying the distribution of the resident oral bacterial biota of the mouse, we observed an unidentified Streptococcus that eventually dominated the microbiota (8). It was found that the strain originated from Jackson Laboratory mice and was not present in Charles River mice.…”

mentioning

confidence: 92%

“…To study the fundamental mechanisms imphcated in the maintenance of homeostasis in the oral cavity, we chose the murine model (1,27,33). Our previous results indicated that the mierobial biota of the oral cavity of BALB/c mice is simple, being limited to only 18 species, among which only a few predominate at any one time: Lactobacillus murinus, staphylococci, Enterococcus faecalis and Streptococcus sanguis II (now Streptococcus oralis) (8,33). Among other mouse strains, a few other bacterial species (21 different species) were detected, but the overall number remained relatively low, confirming the selectivity of this environment (8).…”

mentioning

confidence: 99%

“…Our previous results indicated that the mierobial biota of the oral cavity of BALB/c mice is simple, being limited to only 18 species, among which only a few predominate at any one time: Lactobacillus murinus, staphylococci, Enterococcus faecalis and Streptococcus sanguis II (now Streptococcus oralis) (8,33). Among other mouse strains, a few other bacterial species (21 different species) were detected, but the overall number remained relatively low, confirming the selectivity of this environment (8). A modification of the diet was the only parameter found to affect the composition of the oral microbiota of mice (1).…”

mentioning

confidence: 99%

See 1 more Smart Citation

Colonization of the oral cavity of mice by an unidentified streptococcus

Marcotte

Rodrigue

Coulombe

et al. 1995

Oral Microbiology and Immunology

Self Cite

View full text Add to dashboard Cite

While studying the oral bacterial biota of mice, we observed an unidentified streptococcus (TG) that eventually became the dominant species of the oral cavities of all other mice in our animal facility. We found that the strain is indigenous to Jackson Laboratory mice but is absent in animals from Charles River Laboratories. TG was also transmitted from artificially contaminated BALB/c mice to the oral cavities of 4 other mouse strains. Streptococcus sp. TG stimulated the secretory and systemic immune systems of artificially contaminated Charles River BALB/c mice but did not provoke clinical symptoms. The increase in antibody level to TG did not prevent its colonization and persistence in these mice. In mice from Jackson Laboratory, the secretory and systemic immune response to TG was significantly lower. In vitro, Streptococcus sp. TG inhibited murine oral lactobacilli and staphylococci, probably due to the production of hydrogen peroxide.

show abstract

Distribution of the Resident Oral Bacterial Populations in Different Strains of Mice

Cited by 8 publications

References 24 publications

Evolution of resident oral bacterial biota in BALB/c mice during pregnancy and lactation

Evolution of resident oral bacterial biota in BALB/c mice during pregnancy and lactation

Comparison of the indigenous oral microbiota and immunoglobulin responses of athymic (nu/nu) and euthymic (nu/+) mice

Colonization of the oral cavity of mice by an unidentified streptococcus

Contact Info

Product

Resources

About