Distribution of CKD and Hypertension in 13 Towns in Hail Region, KSA

Ahmed, Hussain Gadelkarim; Ginawi, Ibrahim Abdelmajeed; Haridi, Hassan Kasim; Eltom, Faris Margani; Al-hazimi, Awdah M.

doi:10.21608/eajbsc.2014.16028

Cited by 5 publications

(4 citation statements)

References 12 publications

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“… 17 in the Hail region among 2946 participants depicted a CKD prevalence rate of 9.4%. Another cross-sectional study in the Hail region (2012) reported a 7.8% CKD prevalence among 2800 participants, with a female population distribution of 56.2% 18 . Mousa and colleagues highlighted that over 20 000 people in Saudi Arabia are currently receiving dialysis, and 9810 kidney transplant recipients are under follow-up care.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and assessment of risk factors of chronic kidney disease in the ASIR region of Saudi Arabia

Alshahrani,

Almalki,

Hasoosah

et al. 2024

Annals of Medicine &Amp; Surgery

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Introduction: Chronic kidney disease (CKD) is a major health concern in Saudi Arabia. The prevalence of CKD and associated risk factors in Saudi Arabia’s general population are not efficiently studied. The goal of this research is to determine the prevalence rate of CKD in the ASIR region and its associated epidemiological risk factors. Methodology: This is a cross-sectional study that used a comprehensive direct questionnaire to collect data on CKD prevalence and risk factors in the ASIR region of Saudi Arabia. The study was carried out in different age groups. Demographic characteristics, presence of CKD, and associated factors such as a history of acute kidney disease, obstructive sleep apnea, family history, history of non-steroid anti-inflammatory drugs (NSAID), smoking status, comorbidities, and history of periodontal diseases were asked. The survey tool was validated through a pilot study, and a statistical p-value of 0.05 was considered significant. Results: A total of 967 participants were included in the study, with a CKD prevalence rate of 1.9%. Gender, history of acute kidney disease, obstructive sleep apnea, family history of kidney disease, smoking, diabetes, peptic ulcer disease, hypertension and hyperlipidemia were commonly found to be associated with CKD. A binary logistic regression model was carried out to assess the risk factors for CKD. Gender, history of acute kidney disease, family history of kidney disease, obstructive sleep apnea, smoking status, peptic ulcer, diabetes, hypertension, hyperlipidemia, hypertension and diabetes, two or more comorbidities and NSAID use had an increased risk of CKD. Conclusion: Gender, history of acute kidney disease, obstructive sleep apnea, family history, smoking, diabetes, hypertension, peptic ulcer, hyperlipidemia, multi-comorbidity, and use of NSAIDs are all associated with an increased risk of CKD. The prevalence of CKD in this study is comparatively lower when compared to other regions in Saudi Arabia.

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Section: Discussionmentioning

confidence: 99%

Prevalence and assessment of risk factors of chronic kidney disease in the ASIR region of Saudi Arabia

Alshahrani,

Almalki,

Hasoosah

et al. 2024

Annals of Medicine &Amp; Surgery

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“…Most CHD patients were rural inhabitants. Studies from the area have shown that CKD and CHD risk factors such as hypertension, diabetes, and hypercholesterolemia are more frequent in Saudi rural areas than in urban [20][21][22].…”

Section: Discussionmentioning

confidence: 99%

Association of Chronic Kidney Disease and Coronary Heart Disease in A Series of Saudi Patients

2023

Cardiolog Res Cardiovasc Med

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Objectives: this study aimed to assess the association between CKD and coronary heart disease (CHD) in a series of Saudi patients. Methods: This study investigated 2700 Saudi volunteers during a cross-sectional survey conducted in Hai'l region. Participants were included based randomly regardless of age or gender. CKD stage was determined according to GFR estimation using creatinine level, age, and sex. Results: The risk of CHD associated with CKD, the relative risk (RR), and the 95% confidence interval was RR (95%CI) = 8.5045(4.5035 to 16.0602), P < 0.0001. The risk of CHD among patients above 41 years was statistically significant, with the RR (95%CI) = 5.6978 (2.3849 to 13.6126), P = 0.0001. The risk of CHD associated with FHRD was the RR (95%CI) = 5.2567 (2.5146 to 10.9891), P = 0.0001. Conclusion: There is a statistically significant association between CKD and CHD in a population with shared risk factors such as hypertension, diabetes, and obesity. A statistically significant positive association between CKD & CHD and Saudi rural inhabitants, family history of renal disease, and exsmoking.

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“…However, there are no nationwide population-based registries that reflect the true burden of CKD and ESKD, and it is possible that true estimates exceed what is reflected in this current guideline. As a result, current estimates are primarily based on single-center observational studies or studies conducted almost or more than a decade ago [15][16][17][18].…”

Section: Epidemiologymentioning

confidence: 99%

Adapting Clinical Practice Guidelines for Chronic Kidney Disease: Blood Pressure Management and Kidney Replacement Therapy in Adults and Children in the Saudi Arabian context using the GRADE-ADOLOPMENT methodology

Alhasan¹,

Yepes-Núñez²,

Askandarani³

et al. 2023

Preprint

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Background: This practice guideline was developed by the Chronic Kidney Disease (CKD) Task Force, which was composed of clinical and methodological experts. The Saudi Arabian Ministry of Health and its Health Holding Company commissioned this guideline project to support the realization of the Vision 2030's healthcare transformation pillar. Methods: The guideline synthesis was guided by the GRADE-ADOLOPMENT methodology. Results: The final adoloped guideline addressed 12 clinical questions on blood pressure management in patients with CKD through a set of recommendations and performance measures. The recommendations included antihypertensive agents in children, non-renin angiotensin system inhibition (Non-RASi) vs RASi in adults, intensive vs standard blood pressure targets, early vs late assessment for kidney replacement therapy (KRT), late vs early preparation strategy for KRT, CKD symptoms during assessment for KRT or conservative management, initiation of KRT in patients with deteriorating CKD, choice of KRT modality or conservative management in certain CKD patient groups, changing or discontinuing KRT modalities, review frequency for KRT or conservative management, and Information, education and support. Conclusions: These conditional recommendations were based on low to very low certainty of evidence that highlights the need for high-quality randomized trials comparing different antihypertensive agents in patients with CKD.

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Distribution of CKD and Hypertension in 13 Towns in Hail Region, KSA

Cited by 5 publications

References 12 publications

Prevalence and assessment of risk factors of chronic kidney disease in the ASIR region of Saudi Arabia

Prevalence and assessment of risk factors of chronic kidney disease in the ASIR region of Saudi Arabia

Association of Chronic Kidney Disease and Coronary Heart Disease in A Series of Saudi Patients

Adapting Clinical Practice Guidelines for Chronic Kidney Disease: Blood Pressure Management and Kidney Replacement Therapy in Adults and Children in the Saudi Arabian context using the GRADE-ADOLOPMENT methodology

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