Association of Chronic Kidney Disease and Coronary Heart Disease in A Series of Saudi Patients

Abstract

Objectives: this study aimed to assess the association between CKD and coronary heart disease (CHD) in a series of Saudi patients. Methods: This study investigated 2700 Saudi volunteers during a cross-sectional survey conducted in Hai'l region. Participants were included based randomly regardless of age or gender. CKD stage was determined according to GFR estimation using creatinine level, age, and sex. Results: The risk of CHD associated with CKD, the relative risk (RR), and the 95% confidence interval was RR (95%CI) = 8.5045(4.5035 to 16.0602), P < 0.0001. The risk of CHD among patients above 41 years was statistically significant, with the RR (95%CI) = 5.6978 (2.3849 to 13.6126), P = 0.0001. The risk of CHD associated with FHRD was the RR (95%CI) = 5.2567 (2.5146 to 10.9891), P = 0.0001. Conclusion: There is a statistically significant association between CKD and CHD in a population with shared risk factors such as hypertension, diabetes, and obesity. A statistically significant positive association between CKD & CHD and Saudi rural inhabitants, family history of renal disease, and exsmoking.