Distribution of ABO and Rh (D) Blood groups in India: A systematic review

Patidar, Gopal Kumar; Dhiman, Yashaswi

doi:10.1111/voxs.12576

Cited by 18 publications

(23 citation statements)

References 47 publications

(10 reference statements)

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“…Blood Group (BG) distribution of subjects in our study was similar to national reference based on a recent systematic review. 13 Sero-positivity was significantly different between different groups, being highest for blood group type AB (10•19%) followed by B (9•94%), O (7•09%) and A (6•97%). Blood Group O was found to be associated with a lower sero-positivity rate, with an OR of 0•76 (95 % CI 0•64 -0•91, p=0•018) vs Non O blood group types, while B appeared to be at high-risk with an OR of 1•36 (95 % CI 1•15 -1•61, p=0•001).…”

Section: Survey Based Correlates Of Seropositivitymentioning

confidence: 92%

“…Apart from gender and age, distribution of the other variables recorded in CSIR-cohort (prevalence of smoking, diet, physiological parameters like ABO blood group type) were similar to the national averages and the sample can be considered representative. [13][14][15] The univariate associations are shown in Figure 3, separately for each gender. Due to gender imbalance and possible confounding between various parameters, significance of associations was further tested in a balanced iterative logistic regression (Figure 3 Supplement Figure 1).…”

Section: Survey Based Correlates Of Seropositivitymentioning

confidence: 99%

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Insights from a Pan India Sero-Epidemiological survey (Phenome-India Cohort) for SARS-CoV2

Naushin

Sardana

Ujjainiya

et al. 2021

eLife

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To understand the spread of SARS-CoV2, in August and September 2020, the Council of Scientific and Industrial Research (India), conducted a sero-survey across its constituent laboratories and centers across India. Of 10,427 volunteers, 1058 (10.14%) tested positive for SARS CoV2 anti-nucleocapsid (anti-NC) antibodies; 95% of which had surrogate neutralization activity. Three-fourth of these recalled no symptoms. Repeat serology tests at 3 (n=607) and 6 (n=175) months showed stable anti-NC antibodies but declining neutralization activity. Local sero-positivity was higher in densely populated cities and was inversely correlated with a 30 day change in regional test positivity rates (TPR). Regional seropositivity above 10% was associated with declining TPR. Personal factors associated with higher odds of sero-positivity were high-exposure work (Odds Ratio, 95% CI, p value; 2∙23, 1∙92–2∙59, <0.0001), use of public transport (1∙79, 1∙43–2∙24, <0.0001), not smoking (1∙52, 1∙16–1∙99, 0∙0257), non-vegetarian diet (1∙67, 1∙41–1∙99, <0.0001), and B blood group (1∙36,1∙15-1∙61, 0∙001).

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Section: Survey Based Correlates Of Seropositivitymentioning

confidence: 92%

Section: Survey Based Correlates Of Seropositivitymentioning

confidence: 99%

Insights from a Pan India Sero-Epidemiological survey (Phenome-India Cohort) for SARS-CoV2

Naushin

Sardana

Ujjainiya

et al. 2021

eLife

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“…Based on Rh type, Rh(D) positive and Rh(D) negative population were 94.13% and 5.87%, respectively. 9 In the United States of America, the frequency distribution of blood group O varies from 39.8% in Asian donors to 56.5% in Hispanic donors, and the proportion of Rh (D) negative varies from 1.7% in Asian donors to 17.3% in White non-Hispanic donors. 6 Blood group A (43.8%) was the most frequent and AB the least frequent, and Rh positivity rate was 85% in Turkey.…”

Section: Introductionmentioning

confidence: 99%

Distribution of ABO and Rhesus Blood Group Phenotypes Among Blood Donors at Bahir Dar Blood Bank, Amhara, Northwest Ethiopia: A Retrospective Cross-Sectional Study

Legese¹,

Shiferaw

Tamir³

et al. 2021

JBM

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Background Among the blood group antigens identified, ABO and Rhesus are the most important in transfusion medicine. ABO blood group antigens are the most immunogenic followed by Rhesus (D antigen). These blood groups’ frequency distribution varies among different regions and races of the world. This study aimed to identifying the frequency distribution of ABO blood group and rhesus factors among blood donors in Ethiopia. Methods and Materials Aretrospective cross-sectional study was conducted from September 12/2019 to March 18/2021 at Bahir Dar blood bank service. After getting a permission letter from the blood bank, data were collected from the blood bank donor data registration system, and descriptive statistical results were presented in number (frequency) and percentage. A Chi-square test was used to show the difference in the frequency distribution of ABO and Rh blood groups among sex and blood donation site. Results From 40,053 blood donors, 67.7% were males and younger donors (within the age range of 18–24 years) account for 63.7%. All donations were from voluntary non-remunerated blood donors. The most common blood group was blood group O (41.5%) followed by A (29.8), B (23.2%), and AB (5.5%). Considering ABO and Rh blood group altogether blood group O positive with 37.9% was the predominant blood group followed by A positive (27.2%), B positive (21.4%), AB positive (5%), O negative (3.6%), A negative (2.6%), B negative (1.8%), and AB negative (0.4%). The majority of study participants were 91.5% Rh (D) positive. Conclusion This study showed that blood group O was the predominant followed by A, B, and AB and most of the blood donors’ blood groups were Rh-positive (91.5%). About 68.9% of the total donations were from the first time donor.

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“…Blood Group (BG) distribution of individuals in our study was similar to national reference based on a recent systematic review (eTable 2). 20 Sero-prevalence was highest for blood group type AB (10·19%) followed by group B (9·94%), group O (7·09%) and the lowest for group A (6·97%). Blood O was observed to be protective, with an odds ratio of 0·76 (95 % CI 0·64 −0·91, p=0·018) vs Non O blood group types, while B appeared to be associated with higher sero-positivity 1·36 (95 % CI 1·15 −1·61, p=0·001).…”

Section: Resultsmentioning

confidence: 89%

Section: Resultsmentioning

confidence: 99%

Insights from a Pan India Sero-Epidemiological survey (Phenome-India Cohort) for SARS-CoV-2

Naushin

Sardana

Ujjainiya

et al. 2021

Preprint

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BackgroundIndia has been amongst the most affected nations during the SARS-CoV2 pandemic, with sparse data on country-wide spread of asymptomatic infections and antibody persistence. This longitudinal cohort study was aimed to evaluate SARS-CoV2 sero-positivity rate as a marker of infection and evaluate temporal persistence of antibodies with neutralization capability and to infer possible risk factors for infection.MethodsCouncil of Scientific and Industrial Research, India (CSIR) with its more than 40 laboratories and centers in urban and semi-urban settings spread across the country piloted the pan country surveillance. 10427 adult individuals working in CSIR laboratories and their family members based on voluntary participation were assessed for antibody presence and stability was analyzed over 6 months utilizing qualitative Elecsys SARS CoV2 specific antibody kit and GENScript cPass SARS-CoV2 Neutralization Antibody Detection Kit. Along with demographic information, possible risk factors were evaluated through self to be filled online forms with data acquired on blood group type, occupation type, addiction and habits including smoking and alcohol, diet preferences, medical history and transport type utilized. Symptom history and information on possible contact and compliance with COVID 19 universal precautions was also obtained.Findings1058 individuals (10·14%) had antibodies against SARS-CoV2. A follow-up on 346 sero-positive individuals after three months revealed stable to higher antibody levels against SARS-CoV2 but declining plasma activity for neutralizing SARS-CoV2 receptor binding domain and ACE2 interaction. A repeat sampling of 35 individuals, at six months, revealed declining antibody levels while the neutralizing activity remained stable compared to three months. Majority of sero-positive individuals (75%) did not recall even one of nine symptoms since March 2020. Fever was the most common symptom with one-fourth reporting loss of taste or smell. Significantly associated risks for sero-positivity (Odds Ratio, 95% CI, p value) were observed with usage of public transport (1·79, 1·43 – 2·24, 2·81561E-06), occupational responsibilities such as security, housekeeping personnel etc. (2·23, 1·92 – 2·59, 6·43969E-26), non-smokers (1·52, 1·16 – 1·99, 0·02) and non-vegetarianism (1·67, 1·41 – 1·99, 3·03821E-08). An iterative regression analysis was confirmatory and led to only modest changes to estimates. Predilections for sero-positivity was noted with specific ABO blood groups -O was associated with a lower risk.InterpretationIn a first-of-its-kind study from India, we report the sero-positivity in a country-wide cohort and identify variable susceptible associations for contacting infection. Serology and Neutralizing Antibody response provides much-sought-for general insights on the immune response to the virus among Indians and will be an important resource for designing vaccination strategies.FundingCouncil of Scientific and Industrial Research, India (CSIR)

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Distribution of ABO and Rh (D) Blood groups in India: A systematic review

Cited by 18 publications

References 47 publications

Insights from a Pan India Sero-Epidemiological survey (Phenome-India Cohort) for SARS-CoV2

Insights from a Pan India Sero-Epidemiological survey (Phenome-India Cohort) for SARS-CoV2

Distribution of ABO and Rhesus Blood Group Phenotypes Among Blood Donors at Bahir Dar Blood Bank, Amhara, Northwest Ethiopia: A Retrospective Cross-Sectional Study

Insights from a Pan India Sero-Epidemiological survey (Phenome-India Cohort) for SARS-CoV-2

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