The terahertz (THz) regime (0.1-10 THz) is rich with emerging possibilities in sensing, imaging and communications, with unique applications to screening for weapons, explosives and biohazards, imaging of concealed objects, water content and skin. Here we present initial surveys to evaluate the possibility of sensing plastic explosives and bacterial spores using field-deployable electronic THz techniques based on short-pulse generation and coherent detection using nonlinear transmission lines and diode sampling bridges. We also review the barriers and approaches to achieving greater sensing-at-a-distance (stand-off) capabilities for THz sensing systems. We have made several reflection measurements of metallic and non-metallic targets in our laboratory, and have observed high contrast relative to reflection from skin. In particular, we have taken small quantities of energetic materials such as plastic explosives and a variety of Bacillus spores, and measured them in transmission and in reflection using a broadband pulsed electronic THz reflectometer. The pattern of reflection versus frequency gives rise to signatures that are remarkably specific to the composition of the target, even though the target's morphology and position is varied. Although more work needs to be done to reduce the effects of standing waves through time-gating or attenuators, the possibility of mapping out this contrast for imaging and detection is very attractive.