Distinct cytologic features of spindle cell lipoma

Correlation between fine‐needle aspiration cytology and histopathology in the evaluation of cutaneous and subcutaneous masses from dogs and cats

“…An exception was in the diagnosis of hemangiopericytoma in dogs, which was based on the key morphologic features of relatively good cellularity, cytoplasmic vacuoles, binucleation (observed in all cases), and multinucleated cells, which can be “crown cells” 18. In humans, multinucleated cells with the same morphology as crown cells are called “floret cells” and have been described both in angiofibromas27 and some lipomas 28,29…”

Lipoma of the tongue diagnosed by fine‐needle aspiration cytology

“…Some cytologic clues can hint at specific histotypes: for example, mast cells can suggest the presence of myxoid changes. 11,12 FNAC reports of tongue lipomas are very rare [11][12][13][14] and have been useful in distinguishing lipomas from other possible soft tissue tumors arising in the tongue. [11][12][13][14] The present case is added to the above-reported series because of two specific peculiarities: its size (7 cm) ranks it among the largest in the literature, and additionally it is one of the few tongue lipomas diagnosed by FNAC so far.…”

“…11,12 FNAC reports of tongue lipomas are very rare [11][12][13][14] and have been useful in distinguishing lipomas from other possible soft tissue tumors arising in the tongue. [11][12][13][14] The present case is added to the above-reported series because of two specific peculiarities: its size (7 cm) ranks it among the largest in the literature, and additionally it is one of the few tongue lipomas diagnosed by FNAC so far. 11,12 Considering the relative rarity of tongue masses and, in contrast, the wide variety of possible lesions, including lipoma, FNAC is helpful in their pre-operative diagnosis and in the orientation of surgical approach.…”

Spindle cell lipoma masquerading as lipomatous pleomorphic adenoma: A diagnostic dilemma on fine needle aspiration cytology

“…[6] Cytogenetic analysis reveal characteristic karyotypic aberrations notably loss of material from long arms of chromosomes 13 and 16. Domanski et al .,[1] in the first ever series on FNA of spindle cell lipoma summarized the cytological features as a mixture of mature adipocytes, uniform spindle cells, and collagen fibers in varying proportions. The spindle cells have pale, poorly defined cytoplasm with fusiform/ovoid basophilic nuclei showing mild anisokaryosis and inconspicuous nucleoli.…”

“…Although few studies addressing the histological findings of spindle cell lipoma have been described, only a few descriptions of fine needle aspiration cytology (FNAC) findings have been documented in literature. [1–4] Needle aspirates from spindle cell lipoma show some cytological features common to other fatty/spindle cell or myxoid lesions, benign as well as malignant. We present a case of a 55-year-old male with a nodular swelling over left cheek, which due to its location (in the parotid region) as well as prominent myxoid background prompted us to include the lipomatous salivary lesions in differential diagnosis.…”