Correlation between fine‐needle aspiration cytology and histopathology in the evaluation of cutaneous and subcutaneous masses from dogs and cats

Ghisleni, Gabriele; Roccabianca, P.; Ceruti, Roberta; Stefanello, Damiano; Bertazzolo, Walter; Bonfanti, Ugo; Caniatti, M.

doi:10.1111/j.1939-165x.2006.tb00084.x

Cited by 81 publications

(78 citation statements)

References 22 publications

(27 reference statements)

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“…Cytology is not very effective in further differentiating a mesenchymal lesion [40] because of morphological similarities between reactive and neoplastic fibroblasts; therefore the diagnosis 'soft tissue sarcoma' is usually based on histological evaluation. The EIR for STS found in our histologically diagnosed data-set (EIR: 114) is higher than some previous publications in which an IR of 35 was reported, [38] but somewhat lower than the IR found by Dobson et al (IR: 142) [34].…”

Section: Estimated Incidence Ratesmentioning

confidence: 99%

A longitudinal study of ABC transporter expression in canine multicentric lymphoma

Zandvliet

Teske

Schrickx

et al. 2015

The Veterinary Journal

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Background: A genetic predisposition for certain tumour types has been proven for some dog breeds. Some studies have suggested that this may also be true for the Golden retriever breed. The present study aimed to examine a possible existence of a tumour (type) predisposition in the Dutch population of Golden retrievers by evaluating annual estimated incidence rates compared to incidence rates from previous publications. A second aim was to evaluate whether incidences of various tumours differed as related to the diagnostic method chosen, being either cytology or histology. Results: Tumours submitted to Utrecht University during the period 1998-2004 diagnosed either by means of cytology (n = 2,529) or histology (n = 2,124), were related to an average annual Dutch kennel club population of 29,304 Golden retrievers. Combining individual tumours from both the cytological and the histopathological data-set resulted in an annual estimated incidence rate of 2,242 for 100,000 dog-years at risk regarding tumour development in general. The most common cytological tumor diagnoses were 'fat, possibly lipoma' (35%), mast cell tumour (21%) and non-Hodgkin lymphoma (10%). The most commonly diagnosed tumours by histology were mast cell tumour (26%), soft tissue sarcomas (11%) and melanoma (8%). Both the cytological and histopathological data-sets, showed variation; in patient age distribution, age of onset and incidence of various tumours. Conclusion: Comparing our data with previous reports in non-breed-specified dog populations, the Golden retriever breed shows an increased risk for the development of tumours in general, as well as an increased risk for the development of specific tumour types, including the group of soft tissue sarcomas. Variations in age, location and incidence of various tumours were observed between the two data-sets, indicating a selection bias for diagnostic procedure.

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Section: Estimated Incidence Ratesmentioning

confidence: 99%

A longitudinal study of ABC transporter expression in canine multicentric lymphoma

Zandvliet

Teske

Schrickx

et al. 2015

The Veterinary Journal

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“…Ghisleni et al (2006), encontraram dentre os 175 tumores, 69 (39%) de origem mesenquimal, 56 (32%) de células redondas e 51 (29%) epiteliais. Mesmo que os tumores tenham sido escolhidos ao acaso, nota-se que a frequência na classificação dos mesmos mantém-se semelhante entre os trabalhos, inferindo uma linearidade na divisão destes grupos.…”

Section: Resultsunclassified

“…Os resultados obtidos neste estudo confirmam os registros da literatura, que definem a citopatologia como um método seguro, rápido e eficaz na prática clínica, para diferenciação de lesões neoplásicas e não neoplásicas (Ghisleni et al 2006, Gupta et al 2011, Nigam et al 2013. A concordância entre os exames citopatológico e histopatológico para definir se o tumor era neoplásico ou não foi de 91,91%.…”

Section: Resultsunclassified

“…Obteve-se divergência em apenas três tumores, que foram diagnosticados como neoplásico na histopatologia e não neoplásico na citopatologia. Resultados semelhantes foram obtidos por Ghisleni et al (2006), que encontraram 176 neoplasias diagnosticadas pela citopatologia, confirmadas por meio da histopatologia, e em apenas um caso a citopatologia recebeu diagnóstico falso positivo. No presente estudo, a insuficiência de material para análise devido à hemodiluição ou baixa celularidade, contribuiu para que alguns resultados fossem considerados não neoplásicos pela citopatologia.…”

Section: Resultsunclassified

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Comparação entre a citopatologia por biopsia com agulha fina e a histopatologia no diagnóstico das neoplasias cutâneas e subcutâneas de cães

Braz

Brum²,

Leal

et al. 2016

Pesq. Vet. Bras.

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ABSTRACT. - The cutaneous cancers are among the most frequently diagnosed in veterinary medicine before it is sought that the diagnosis of these tumors are fast and effective. In veterinary medicine the use of cytology as a method for diagnosis has increased. Therefore is necessary that studies demonstrate the technical efficiency so that it can be used as only tool. This study aimed to compare the diagnosis made by cytological and histological techniques. Skin and subcutaneous tumors of dogs and their neoplastic type are more easily diagnosed by cytology and are the most prevalent tumors in this animal spécies, attended by two veterinary hospitals in Campo Grande/MS from March 2012 to December 2013. Tumor cell samples were collected by fine needle aspiration and surgical punch of 91 dogs. The cytological results showed an efficacy of 69.69% in relation to histopathology. For differentiating between neoplastic and non-neoplastic growth, the efficiency increases to 91.91%. In order to differentiate benign from malignant tumors, it was possible to find an agreement in the order of 68.13%. The most prevalent tumors were mastocytoma, followed by lipoma, fibrosarcoma and basal cell tumor.

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“…For cell morphology evaluation, the technique allows differentiating inflammatory processes, hyperplasias, neoplasms and metastasis sites. Likewise, it permits establishing and grading prognoses, according to the degree of aggressiveness, monitoring and managing chemotherapy treatments, defining surgical margins, following the lesion growth, and validating indication for euthanasia during surgery [2]. The main FNAC limitation, unlike the histopathological examination, is related to the impossibility to obtain data on the architecture of lesion, but provides a diagnostic result with greater ease.…”

Section: Introductionmentioning

confidence: 99%

Fine Needle Aspiration Cytology in the Diagnosis of Canine Cutaneous Transmissible Venereal Tumor— Case Report

Rocha¹,

Tremori²,

Carneiro³

2014

OJVM

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Fine needle aspiration cytology (FNAC) has been widely used in the diagnosis of lesions from various origins, especially neoplastic. The technique is simple, fast, safe, minimally invasive and inexpensive, which allows through the evaluation of cell morphology to establish prognosis, delineate surgical margins, monitor lesion growth, validate indication euthanasia during surgery and monitor chemotherapy protocols. Diagnosis of canine transmissible venereal tumor (TVT) can be accomplished with ease and precision, even to be rated, according to the degree of aggressiveness. The study objective was to demonstrate the effectiveness of the examination in the diagnosis of TVT plasmacytoid type. An eight-month dog presented to the veterinary hospital (HV), faculty of veterinary medicine and animal science, FMVZ, UNESP-Univ Estadual Paulista with clinical suspicion of cutaneous lymphoma. By presenting multiple nodular lesions, FNAC was performed to cytological diagnosis. The tissue showed cells consistent with TVT. The animal was treated, and a total cure was achieved. According to the literature, TVT mainly affects external genitalia of sexually active animals and its transmission is more frequent during intercourse. In addition, animals sexually immature and without contact to the street dogs, hardly have injuries by TVT. In this case, verrucous and ulcerated lesions on the vulva of its mother during pregnancy and childbirth infected the animal. Diffuse and predominant dorsal injuries occurred due to both exfoliation of breast tumor during delivery and immunosuppression of pup at birth, thus favoring an atypical transmission.

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Correlation between fine‐needle aspiration cytology and histopathology in the evaluation of cutaneous and subcutaneous masses from dogs and cats

Abstract: The results of this study confirmed FNAC as a reliable and useful diagnostic procedure for the evaluation of palpable cutaneous and subcutaneous lesions in small animal practice.

Cited by 81 publications

References 22 publications

A longitudinal study of ABC transporter expression in canine multicentric lymphoma

A longitudinal study of ABC transporter expression in canine multicentric lymphoma

Comparação entre a citopatologia por biopsia com agulha fina e a histopatologia no diagnóstico das neoplasias cutâneas e subcutâneas de cães

Fine Needle Aspiration Cytology in the Diagnosis of Canine Cutaneous Transmissible Venereal Tumor— Case Report

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