Distinct contributions of A314S and novel R667Q substitutions of acetylcholinesterase 1 to carbofuran resistance of Chilo suppressalis Walker

Abstract

With the enhancing activity of the R667Q substitution, A314S is the major CsAChE1 substitution responsible for fitness-cost compensation and increased insensitivity to AChE inhibitors. The lower insensitivity of A314S-substituted CsAChE1 to chlorpyrifos-oxon suggests that chlorpyrifos could be an alternative insecticide for managing carbofuran-resistant field C. suppressalis in Taiwan. © 2015 Society of Chemical Industry.

An overview of the mitigating mechanisms of the fitness cost of mutations associated with pesticide resistance in arthropods

“…Over time, different mutations can accumulate in the same locus so that catalytic efficiency can be restored, or the compensation can come from an increase in the affinity of binding to the substrate. One or more compensatory mutations have been described in the GABA receptor gene of Drosophila simulans (LE GOFF et al, 2005) and Nilaparvata lugens (ZHANG et al, 2016), in the acetylcholinesterase gene from Chilo suppressalis (DAI et al, 2016), Drosophila melanogaster (SHI et al, 2004) and Tetranychus urticae (KWON et al, 2012), and in the gene of the sodium channel (Kdr mutations) from Musca domestica (KASAI et al, 2017), Aedes aegypti (LINSS et al, 2014) and Anopheles gambiae (JONES et al, 2012).…”

Field Efficacy of Nicotiana tabacum L. var Virginia Extract against Coffee Borer Beetle (Hypothenemus hampei) Attacking Coffee Berries in Plantation Area

“…is insecticide effectively kills CBBs beetle pest by contact and stomach poisoning as the effect from its active compound. However, indiscriminate use of carbaryl and also carbofuran insecticide leaves the residue and leads to the emergence of resistant to many insects such as the peach potato aphid Myzus persicae [10], the German cockroach Blattella germanica [11], the striped stem borer Chilo suppressalis [12], and also Hypothenemus hampei [13,14]. e hazardous residue can be absorbed into the coffee beans and can also contaminate the environment for a long-term period [13].…”