Distance-dependent quenching and enhancing of electrochemiluminescence from tris(2, 2′-bipyridine) ruthenium (II)/tripropylamine system by gold nanoparticles and its sensing applications

Gai, Qi-Qi; Wang, Dongmei; Huang, Rong; Liang, Xia-Xia; Wu, Honglin; Tao, Xingyi

doi:10.1016/j.bios.2018.07.023

Cited by 31 publications

(15 citation statements)

References 37 publications

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“…Therefore, a scan rate of 0.1 V•s -1 was employed for further experiments. It is well known that Ru(bpy)3 2+ can react with amines such as tripropylamine [28], melamine [29], and dopamine [30] to emit ECL. Therefore, the mechanism of ECL emission in the presence of acrylamide can be inferred based on this.…”

Section: Optimization Of Ecl Measurement Conditionsmentioning

confidence: 99%

Novel Detection of Acrylamide by Electrochemiluminescence Sensor and Optical Imaging Analysis

Yang¹

2019

International Journal of Electrochemical Science

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Acrylamide, a carcinogen with debilitating effects on human health, was detected by electrochemiluminescence (ECL) measurement using Ru(bpy)3 2+ as the luminophore. Under the optimum conditions, Pt electrode as the working electrode showed a superior linear detection in the range 5 μM-10 mM, with a detection limit of 1.2 µM (S/N = 3). Moreover, a remote wireless camera was employed to collect the digital images of the ECL emission. These images were converted from RGB (Red, Green, Blue) model to HSV (Hue, Saturation, Value) model using the MATLAB software. It was found that Value (V) in the HSV model had a linear relationship with the logarithm of the acrylamide concentration, suggesting that acrylamide could be detected in levels of 5 μM using optical imaging. The ECL method for detecting acrylamide was proved to be simple and convenient. This is expected to lead to the development of a novel acrylamide detection method for food safety and other fields.

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Section: Optimization Of Ecl Measurement Conditionsmentioning

confidence: 99%

Novel Detection of Acrylamide by Electrochemiluminescence Sensor and Optical Imaging Analysis

Yang¹

2019

International Journal of Electrochemical Science

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“…Several coreactants of Ru(bpy) 3 2 + used in TB aptasensors are tripropylamine (TPrA) [14], SnO 2 [24], etc. So far, Ru (bpy) 3 2 + /TPrA system is still the most successful ECL system to be used [25].…”

Section: Introductionmentioning

confidence: 99%

A Sandwich‐type Electrochemiluminescence Aptasensor for Thrombin Based on Functional Co‐polymer Electrode Using Ru(bpy)₃²⁺ Doped Nanocomposites as Signal‐amplifying Tags

Shan

Gong

et al. 2019

Electroanalysis

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Herein, a signal‐on sandwich‐type electrochemiluminescence (ECL) aptasensor for the detection of thrombin (TB) was proposed. The graphene (GR) doped thionine (TH) was electropolymerized synchronously on the bare glassy carbon electrode (GCE) to form co‐polymer (PTG) electrode. The gold nanoparticles (AuNPs) were decorated on the surface of the PTG by in‐situ electrodeposition, and the functional co‐polymer (PTG‐AuNPs) electrode was utilized as sensing interface. Then, TB binding aptamer I (TBA I) as capture probes were modified on the PTG‐AuNPs electrode to capture TB, and Ru(bpy)32+/silver nanoparticles doped silica core‐shell nanocomposites‐labeled TB binding aptamer II (RuAg/SiO2NPs@TBA II) were used as signal probes to further bind TB, resulting in a sandwich structure. With the assistant of silica shell and AgNPs, the enrichment and luminous efficiency of Ru(bpy)32+ were significantly improved. Under the synergy of PTG‐AuNPs and RuAg/SiO2NPs, the ECL signal was dramatically increased. The proposed ECL aptasensor displayed a wide linear range from 2 fM to 2 pM with the detection limit of 1 fM, which is comparable or better than that in reported ECL aptasensors for TB using Ru(bpy)32+ and its derivatives as the luminescent substance. The excellent sensitivity makes the proposed aptasensor a promising potential in pharmaceutical and clinical analysis.

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“…Besides, new signals attributed to 8-oxoguanine as a main biomarker of oxidative stress appear on voltammograms [ 22 ]. To decrease working potential and amplify voltammetric signals, redox probes capable of specific interactions with double-stranded (ds-) DNA, e.g., Co phenanthroline [ 23 ], Ru and Co bipyridine complexes [ 24 ], or Methylene blue [ 25 ] are added to the sample. They are implemented in the ds-DNA structure (intercalation) or coordinate at the surface of the DNA helix [ 26 ].…”

Section: Introductionmentioning

confidence: 99%

Electrochemical DNA Sensor Based on Carbon Black—Poly(Neutral Red) Composite for Detection of Oxidative DNA Damage

Kuzin

Kappo

Porfireva

et al. 2018

Sensors

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Voltammetric DNA sensor has been proposed on the platform of glassy carbon electrode covered with carbon black with adsorbed pillar[5]arene molecules. Electropolymerization of Neutral Red performed in the presence of native or oxidatively damaged DNA resulted in formation of hybrid material which activity depended on the DNA conditions. The assembling of the surface layer was confirmed by scanning electron microscopy and electrochemical impedance spectroscopy. The influence of DNA and pillar[5]arene on redox activity of polymeric dye was investigated and a significant increase of the peak currents was found for DNA damaged by reactive oxygen species generated by Cu2+/H2O2 mixture. Pillar[5]arene improves the electron exchange conditions and increases the response and its reproducibility. The applicability of the DNA sensor developed was shown on the example of ascorbic acid as antioxidant. It decreases the current in the concentration range from 1.0 μM to 1.0 mM. The possibility to detect antioxidant activity was qualitatively confirmed by testing tera infusion. The DNA sensor developed can find application in testing of carcinogenic species and searching for new antitumor drugs.

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Distance-dependent quenching and enhancing of electrochemiluminescence from tris(2, 2′-bipyridine) ruthenium (II)/tripropylamine system by gold nanoparticles and its sensing applications

Cited by 31 publications

References 37 publications

Novel Detection of Acrylamide by Electrochemiluminescence Sensor and Optical Imaging Analysis

Novel Detection of Acrylamide by Electrochemiluminescence Sensor and Optical Imaging Analysis

A Sandwich‐type Electrochemiluminescence Aptasensor for Thrombin Based on Functional Co‐polymer Electrode Using Ru(bpy)₃²⁺ Doped Nanocomposites as Signal‐amplifying Tags

Electrochemical DNA Sensor Based on Carbon Black—Poly(Neutral Red) Composite for Detection of Oxidative DNA Damage

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Distance-dependent quenching and enhancing of electrochemiluminescence from tris(2, 2′-bipyridine) ruthenium (II)/tripropylamine system by gold nanoparticles and its sensing applications

Cited by 31 publications

References 37 publications

Novel Detection of Acrylamide by Electrochemiluminescence Sensor and Optical Imaging Analysis

Novel Detection of Acrylamide by Electrochemiluminescence Sensor and Optical Imaging Analysis

A Sandwich‐type Electrochemiluminescence Aptasensor for Thrombin Based on Functional Co‐polymer Electrode Using Ru(bpy)32+ Doped Nanocomposites as Signal‐amplifying Tags

Electrochemical DNA Sensor Based on Carbon Black—Poly(Neutral Red) Composite for Detection of Oxidative DNA Damage

Contact Info

Product

Resources

About

A Sandwich‐type Electrochemiluminescence Aptasensor for Thrombin Based on Functional Co‐polymer Electrode Using Ru(bpy)₃²⁺ Doped Nanocomposites as Signal‐amplifying Tags