Dissipation and Transport of Veterinary Sulfonamide Antibiotics after Manure Application to Grassland in a Small Catchment

Abstract

The heavy use of veterinary antibiotics in modern animal production causes concern about risks of spreading antibiotic resistance after manure applications to agricultural fields. We report on a field study aiming at elucidating the fate of sulfonamide (SA) antibiotics in grassland soils and their transport to surface water. Two controlled manure applications were carried out under different weather conditions. After both applications, the SA concentrations in pore water and the total soil content declined rapidly. This stage of fast decline was followed by a second one during which the SA were rather persistent. More than 15% of the SAs applied were still present in the soil 3 months after application, always exceeding 100 microg/kg topsoil. The apparent SA sorption increased strongly with time. Accordingly, the risk for SA losses to water bodies decreased within 2 weeks to very low values. In contrast to SA concentrations in the soil, losses to the brook were strongly influenced by the weather conditions after the two manure applications. The overall losses were 15 times larger (about 0.5% of applied SA) during the wet conditions of May 2003 compared to the dry conditions following the first application (March 2003).

Occurrence and risk assessment of antibiotics in river water in Hong Kong

“…Sulfonamides are hydrolytically stable and do not easily degrade in water (Stoob et al, 2007). They are likely to be transported to groundwater or surface water due to their high water solubility and weak sorption (Boxall et al, 2002).…”

“…Continuous input, together with the numerous pollution sources, have led to the pseudo-persistent characteristics of antibiotics in the environment (Daughton and Ternes, 1999;Richardson et al, 2005;Khetan and Collins, 2007). Some of the antibiotics, such as sulfonamides which are hydrolytically stable, hard to degrade in water and easy to be transported, are found in larger amounts in groundwater and surface water (Boxall et al, 2002;Stoob et al, 2007). Antibiotics, together with their degradation and metabolic products have been detected in many environmental compartments, including surface water (Tang et al, 2015), river water (Tamtam et al, 2008;Jiang et al, 2011;Li et al, 2015), seawater (Minh et al, 2009;Zou et al, 2011), municipal sewage (Li et al, 2009;Lindberg et al, 2010), sludge (Göbel et al, 2005;Lindberg et al, 2010), soil (Christian et al, 2003), sediment (Pei et al, 2006), groundwater (Standley et al, 2008;Fick et al, 2009;Teijon et al, 2010;López-Serna et al, 2013), and even drinking water (Yiruhan et al, 2010).…”

Ocorrência, comportamento e impactos ambientais provocados pela presença de antimicrobianos veterinários em solos

“…57 Em decorrência de baixos valores de K d e da formação de interações mais fracas com o solo (como interações de van der Waals e ligações de hidrogênio), fármacos como as sulfonamidas (SF) apresentam alta mobilidade no meio ambiente. 15,19,68,72 Deste modo, estes compostos podem ser facilmente lixiviados alcançando águas superficiais e lençóis freáticos e, consequentemente, contaminar a água potável. 13,25 Até o presente momento, poucos trabalhos foram realizados com o intuito de elucidar os mecanismos envolvidos na sorção de antimicrobianos em solos.…”

“…Hamscher et al 18 evidenciaram a presença de tetraciclina (TC) e oxitetraciclina (OTC) a uma profundidade de 30 cm, até 7 meses após a fertilização de solos com esterco líquido de suínos. Stoob et al 19 confirmaram a presença de sulfadiazina (SFZ) e sulfatiazol, 15% em relação à concentração inicial, 3 meses após a aplicação de esterco suíno em solos. AGA et al 20 detectaram OTC, anidro-OTC e anidro-TC 144 dias após a fertilização de solo com esterco de gado.…”

Antibiotic‐induced effects on scaling relationships and on plant element contents in herbs and grasses

“…All of them can subsequently enter the environment through fertilization of soils with manure of livestock animals or through grazing animals. From the soil, they may be transported to ditches, streams, and rivers via runoff (Burkhardt, Stamm, Waul, Singer, & Muller, 2005; Kay, Blackwell, & Boxall, 2005; Stoob, Singer, Mueller, Schwarzenbach, & Stamm, 2007), to groundwater via leaching (Blackwell, Kay, & Boxall, 2007) or may directly be ingested by (nontarget) organisms (Boxall et al., 2006). …”