Disseminated vegetating infantile bromoderma: A dramatic response to systemic steroids

Abstract

Bromoderma is a rare hypersensitivity reaction caused by bromide intake. It was relatively frequent in the early years of the previous century because of the common use of bromide-containing solutions in pediatrics due to their antispasmodic, expectorant, sedative, and anticonvulsant effects. Although recently prohibited in many countries, bromides are still used as an adjuvant anticonvulsant drug and still present in some over the counter antispasmodics and analgesics. Bromoderma usually present with pustular and vegetating lesions that may represent a diagnostic challenge for dermatologists. We describe a severe case of vegetating bromoderma that showed an excellent response to the withdrawal of the bromide-containing medication associated with systemic steroid administration.

Halogenoderma: A Case Report and Review of the Literature

“…The main treatment of HD is the complete cessation of the causative agent and the use of topical or systemic corticosteroids [ 2 , 3 ]. A dramatic response has been observed after using a systemic corticosteroid in a patient with extensive HD [ 12 ]. Silver sulfadiazine cream (a topical antibiotic) with topical corticosteroids has been used successfully in a patient with extensive vegetative bromoderma [ 2 ].…”