Disseminated superficial actinic porokeratosis: Appearance associated with photochemotherapy for psoriasis

Giant verrucous porokeratosis of Mibelli mimicking psoriasis in a patient with psoriasis

“…15 The third group consists of patients with psoriasis and disseminated superficial actinic porokeratosis induced by therapeutic phototherapy or photochemotherapy. 5,16 The small, multiple lesions attenuate or become less prominent after discontinuation of the therapy. Our patient had a single large lesion, with features of a gigantic Mibelli variant of PK and had never been treated with phototherapy.…”

Disseminated superficial actinic porokeratosis in a psoriasis patient with a long‐term sun‐bathing habit

“…Notably, a mutation in ATP2C1 gene, which is the pathogenic gene of HHD, was recently identified in three cases of PAD, suggesting that PAD may be allelic to HHD. 1,5 Regrettably, we could not perform a genetic study in our patient which was not permitted by her parents.…”

“…Until recently, one familial case was described. 1 The disease presents as multiple, skin-colored to white papules or plaques that are most commonly located on the labia majora and adjacent skin in women. The main histological features include acantholysis with variable degrees of dyskeratosis that closely resemble Darier's disease (DD) or Hailey-Hailey disease (HHD).…”

“…DSAP following UV treatment has been described in psoriasis patients. 1,2 We report a case of psoriasis with porokeratosis, which may be associated with UV irradiation by sun-bathing.…”

“…Previously, there have been reports of psoriasis with DSAP following ultraviolet UV-B or psoralen plus ultraviolet A therapy. 1,2 On the other hand, psoriasis associated with porokeratosis without any past history of UV irradiation therapy or systemic immunosuppressive medication has been described. 3 Although our case had not been treated by UV irradiation therapy, the patient had been sun-bathing regularly for almost 30 years, and this may explain the location of the porokeratotic lesions on buttocks and thighs, which are usually non-sun-exposed sites.…”