Dissecting leiomyoma of the uterus with extrauterine extension

Abstract

This tumour illustrates that rare benign smooth muscle tumours can proliferate in dissecting and extrauterine growth patterns, findings that should not be confused with malignant mesenchymal tumours.

Cotyledonoid dissecting leiomyoma of the uterus with intravascular growth: report of two cases

“…The classification of most benign smooth muscle tumors of the uterus is based on the combination of gross and microscopic features such as growth pattern, histologic appearance, association with vessels, and others [1,[3][4][5][6][7]. Therefore, numerous variants of uterine smooth muscle tumors may be manifestations of a common pathological process.…”

Cotyledonoid Dissecting Leiomyoma (Cdl) of Uterus Mimicking Malignancy: A Clinical Dilemma

“…CDL commonly arises from the fundus or posterior aspect of cornu uterus and is characterized by reddish, exophytic, expansile, spongy, bulbous, placenta-like gross appearance by its extrauterine extension into the pelvic cavity raising possibility of malignancy intraoperatively. [1][2][3][4][5][6][7][8][9][10][11][12] which was seen in our case. The dark red appearance of exophytic component is due to venous obstruction and congestion with tan white endophytic parent intramural leiomyoma.…”

Cotyledonoid dissecting leiomyoma of the uterus with intravascular growth in postmenopausal woman: a case presentation

“…There are also abundant collagen fibrils in the matrix [14]. On flow cytometry, cotyledonoid dissecting leiomyoma shows deoxyribonucleic acid diploidy with a relatively low S-phase fraction (5.6%), consistent with a benign nature [13].…”

“…Classification of most benign smooth-muscle tumors of the uterus is based on a combination of gross and microscopic features, for example growth pattern, histologic appearance, association with vessels, and others [2,10,13]. Therefore, numerous variants of uterine smooth-muscle tumors may be manifestations of a common pathological process [14].…”