Disproportionated Rosin Dehydroabietic Acid in Neoprene Surgical Gloves

Siegel, Paul D.; Law, Brandon F.; Fowler, Joseph F.; Fowler, Lynn M.

doi:10.2310/6620.2010.10004

Cited by 6 publications

(3 citation statements)

References 12 publications

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“…Colophonium is commonly found in dentistry products, namely sealants and topical medications. One of the principle components of neoprene surgical gloves is colophony (21). According to our results, the highest was the incidence of sensitization to colophonium (30%) for the group of dental students, with statistical significance, compared to myroxylon pereirae resin, hydroperoxides of limonene, paraben mix, isopropyl myristate, and triclosan.…”

Section: Discussionmentioning

confidence: 51%

Contact sensitization to ingredients of dental materials and cosmetics in dental students: a pilot study

Lyapina

Dencheva

2019

Cent Eur J Public Health

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Objective: The aim of this study was to evaluate the rate of contact sensitization to selected cosmetic allergens, i.e. ingredients of dental materials, in students of dental medicine and dental patients.Methods: A total of 50 participants were included in the study: 40 students of dental medicine exposed to the studied allergens during the course of practical education; and 10 randomly selected dental patients without occupational exposure to the investigated substances served as a control group. All of them were patch-tested with colophonium, myroxylon pereirae resin, paraben mix, fragrance mix I, isopropyl myristate, triclosan, polysorbate 80, compositae mix II, and hydroperoxides of limonene.Results: The sensitization rates for colophonium and polysorbate 80 were the highest. For the group of dental students, we established significantly higher sensitization rate for colophonium compared to the ones for myroxylon pereirae resin and hydroperoxides of limonene (χ 2 = 4.93; p = 0.026), paraben mix (χ 2 = 3.6; p = 0.05), isopropyl myristate (χ 2 = 6.56; p = 0.01), and triclosan (χ 2 = 8.5; p < 0.001); and to polysorbate 80 compared to the ones for myroxylon pereirae resin and hydroperoxides of limonene (χ 2 = 3.97; p = 0.046), isopropyl myristate (χ 2 = 5.47; p = 0.02) and triclosan (χ 2 = 7.34; p = 0.007). Significantly increased concomitant sensitization rate to compositae mix and to hydroperoxides of limonene was established (χ 2 = 12.55; p < 0.001). Generally, the incidence of concomitant sensitization to the studied allergens in the whole studied population was high.Conclusions: Colophonium and polysorbate 80 could be outlined as sensitizers of paramount importance for both dental students and dental patients. We consider the major importance of exposure to colophonium during the course of practical education in dentistry for the onset of the sensitization. Sensitization to compositae mix was observed only among dental students. We consider the leading role of consumer exposure for the onset of the sensitization to triclosan and to hydroperoxides of limonene. Unexpected and unreported reactions of concomitant sensitization were observed.

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Section: Discussionmentioning

confidence: 51%

Contact sensitization to ingredients of dental materials and cosmetics in dental students: a pilot study

Lyapina

Dencheva

2019

Cent Eur J Public Health

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“…Colophonium sensitization might have contributed to the development of allergic contact dermatitis in our patient; however, the manufacturer of the thermal sauna shorts could not be traced to provide any information about colophonium content. A recent study showed that dehydroabietic acid (DHA), one of the major constituents of colophonium, was identified in neoprene surgical gloves, and suggested that neoprene gloves might be a source of DHA exposure, possibly enhanced by the presence of sweat (11).…”

Section: Discussionmentioning

confidence: 99%

Allergic contact dermatitis caused by p‐tert‐butylphenol formaldehyde resin and colophonium in neoprene thermal sauna shorts

2010

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“…Rosin is a mixture consisting of abietic acid and abietic acid derivatives (rosin-related compounds), and they are well-known contact allergens. These compounds are also used as emulsifiers for rubber products, and the concentration and eluted amounts of dehydroabietic acid in chloroprene rubber gloves and artificial sweat (pH 4.7) have been reported 1 . Furthermore, allergic contact dermatitis due to colophonium in chloroprene thermal sauna shorts has also been reported 2 .…”

mentioning

confidence: 99%

Rosin-Related Compounds (Abietic Acid Derivatives) Concentrations in Chloroprene Rubber Products and the Amounts Eluted Into Artificial Sweat

2021

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Disproportionated Rosin Dehydroabietic Acid in Neoprene Surgical Gloves

Cited by 6 publications

References 12 publications

Contact sensitization to ingredients of dental materials and cosmetics in dental students: a pilot study

Contact sensitization to ingredients of dental materials and cosmetics in dental students: a pilot study

Allergic contact dermatitis caused by p‐tert‐butylphenol formaldehyde resin and colophonium in neoprene thermal sauna shorts

Rosin-Related Compounds (Abietic Acid Derivatives) Concentrations in Chloroprene Rubber Products and the Amounts Eluted Into Artificial Sweat

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