Disposable integrated cuvette test for quantitative determination of vitamin C in pharmaceutical products

Koncki, Robert; Lenarczuk, Tomasz; Głąb, Stanisław

doi:10.1016/s0003-2670(98)00653-9

Cited by 24 publications

(7 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Após a eletropolimerização de CoHCF em carbono vítreo, pode ser identificado um par de picos correspondentes a +0,6 e +0, 3 Como última aplicação, cita-se a interessante determinação espectrofotométrica de ácido ascórbico em produtos farmacêuti-cos: filmes de PB foram quimicamente depositados em suportes não condutores (cubetas de plástico) com monitoramento do decréscimo da coloração devido à redução de PB a PW em presença de ascorbatos 71 . Este trabalho foi fruto de publicação anterior 72 , onde os autores apresentaram as potencialidades das aplicações dos filmes de PB como sensores químicos ópticos.…”

Section: Co(ii)/fe(cn)unclassified

Filmes de metal-hexacianoferrato: uma ferramenta em química analítica

Mattos¹,

Gorton²

2001

Quím. Nova

View full text Add to dashboard Cite

Recebido em 26/11/99; aceito em 11/12/00 METAL-HEXACYANOFERRATE FILMS: A TOOL IN ANALYTICAL CHEMISTRY. Chemically modified electrodes based on hexacyanometalate films are presented as a tool in analytical chemistry. Use of amperometric sensors and/or biosensors based on the metal-hexacyanoferrate films is a tendency. This article reviews some applications of these films for analytical determination of both inorganic (e.g. As 3+ , S 2 O 3 2-) and organic (e.g. cysteine, hydrazine, ascorbic acid, gluthatione, glucose, etc.) compounds.Keywords: metal hexacyanoferrate; modified electrodes; biosensor.Revisão Quim. Nova, Vol. 24, No. 2, 200-205, 2001. Foram incluídas algumas considerações práticas na obtenção destes filmes de HCF objetivando demonstrar, entre outras, suas características eletroquímicas. Considerando-se que os filmes baseados em Fe(III) têm sido os mais investigados dentre todos os hexacianometalatos, suas características eletroquímicas foram apresentadas de forma um pouco mais extensa em relação aos demais. INTRODUÇÃO ALGUMAS CARACTERÍSTICAS ELETROQUÍMICAS DOS FILMES Fe(III)/Fe(CN) 6Quando um eletrodo de carbono vítreo é tratado a potencial da ordem de +0,4 V vs. ECS em solução aquosa (meio ácido, pois em meio alcalino há a destruição do filme: Fe (CN

show abstract

Section: Co(ii)/fe(cn)unclassified

Filmes de metal-hexacianoferrato: uma ferramenta em química analítica

Mattos¹,

Gorton²

2001

Quím. Nova

View full text Add to dashboard Cite

show abstract

“…CuCl 2 AE2H 2 O and K 3 Fe(CN) 6 were purchased from Merck (Germany), AA was obtained from Sigma (Germany). Enzymatic test kits for the determination of L-ascorbic acid in foodstuffs by a colorimetric method were obtained from Boehringer Mannheim/R-Biopharm (Germany).…”

Section: Chemicals and Solutionsmentioning

confidence: 99%

“…Before use, the electrodes were electrochemically pre-treated by cycling between 0 and 1 V versus a saturated calomel electrode (SCE) in 0.05 M KCl solution for five to ten cycles until stable cyclic voltammograms (CVs) were obtained. Copper hexacyanoferrate was deposited from a solution containing 10 mM Cu 2+ , 10 mM K 3 Fe(CN) 6 , and 100 mM KCl by one of three methods: chemically, by immersing the electrodes for 50 min in the solution of the precursor salts; galvanostatically, by applying a current of À100 mA cm À2 for 300 s; by cycling the potential 25 times between +0.25 and +0.90 V at a scan rate of 50 mV s À1 . The electrodes were then dried with a stream of hot air, and left at room temperature for 48 h to stabilise.…”

Section: Electrode Preparationmentioning

confidence: 99%

See 1 more Smart Citation

A new, improved sensor for ascorbate determination at copper hexacyanoferrate modified carbon film electrodes

2005

View full text Add to dashboard Cite

A new, improved sensor for the electrocatalytic determination of ascorbate has been developed that has both a low applied operating potential and a low detection limit. The sensor was constructed by depositing copper hexacyanoferrate film either electrochemically or chemically onto carbon film electrode, and it was then characterised by cyclic voltammetry and electrochemical impedance spectroscopy. Chemically deposited films were shown to be the best for ascorbate determination and were used as an amperometric sensor at +0.05 V versus SCE to determine ascorbate in wines and juice. The linear range extended to 5 mM with a limit of detection of 2.1 lM, the sensor was stable for more than four months, and it could be used continuously for at least 20 days.

show abstract

“…Various techniques have been documented for accurate and specific detection of ascorbic acid which include titrimetry with an oxidizing agent [9], capillary electrophoresis [10], spectrophotometry [11], fluorimetry [12], chromatography [13,14], electrochemistry [2,15] which were commonly focused on the analysis of AA in pharmaceuticals and food products. Amongst, electrochemical techniques have extensively been preferred due to its simplicity with respect to time consuming sample pretreatments involving techniques, and their low-cost instrumentation, portability, rapid response, high sensitivity and suitability for in-situ detection in real samples [2].…”

Section: Introductionmentioning

confidence: 99%

Clay-Protein Nanocomposite Based Electrochemical Sensor for the Determination of Ascorbic Acid

Vural

Bolat

Abacı

2020

Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi

View full text Add to dashboard Cite

This paper describes sensitive ascorbic acid (AA) determination on montmorillonite clay and silk protein sericin nanocomposite (MMT-Ser NC) modified pencil graphite electrode (PGE) for the first time. Nanocomposite structures were synthesized by desolvation technique and cross-linked with glutaraldehyde (GA). The synthesized MMT-Ser NC was evaluated by various methods. As a result of the characterization studies, it was determined that the sericin was successfully converged with the montmorillonite structure, and that the MMT-Ser NCs were homogeneous and uniform, with the size of 150 nm and zeta potentials of approximately-27.6 mV. MMT-Ser NC modified electrodes were evaluated by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and scanning electron microscopy (SEM). Under the optimized conditions, working linear range for the modified sensor was found as 10-1000 µM with square wave voltammetry and the limit of detection (LOD) was found as 8 µM. The relative standard deviation for reproducibility was calculated as % 4.82 (n=6). Real sample analysis was performed with drug samples and the recovery values ranged from 94.64% to 111.2%.

show abstract

Disposable integrated cuvette test for quantitative determination of vitamin C in pharmaceutical products

Cited by 24 publications

References 11 publications

Filmes de metal-hexacianoferrato: uma ferramenta em química analítica

Filmes de metal-hexacianoferrato: uma ferramenta em química analítica

A new, improved sensor for ascorbate determination at copper hexacyanoferrate modified carbon film electrodes

Clay-Protein Nanocomposite Based Electrochemical Sensor for the Determination of Ascorbic Acid

Contact Info

Product

Resources

About