Disorders of left ventricular structure and function in chronic uremia: how often, why and what to do with it?

Dyadyk, O.I.; Bagriy, A. E.; Yarovaya, N.F.

doi:10.1016/s1388-9842(99)00057-4

Cited by 24 publications

(23 citation statements)

References 76 publications

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“…The LV systolic dysfunction is a powerfully unfavorable prognostic indicator for individuals undergoing hemodialysis 23 as well as for those submitted to renal transplant 20 . The accountable mechanisms are multifactorial, including coronary failure, anemia, hyperparathyroidism, uremic toxins, malnutrition and prolonged hemodynamic overload 30 . The analysis of the LV systolic function by the echocardiogram is performed annually, usually by methods that evaluate the ejection phase, especially the percentage of shortening and ejection fraction (EF).…”

Section: Left Ventricular Systolic Dysfunctionmentioning

confidence: 99%

Alterações ecocardiográficas em pacientes com insuficiência renal crônica em programa de hemodiálise

Barberato

Pécoits-Filho

2010

Arq. Bras. Cardiol.

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Changes in cardiac structure and function detected by echocardiography are common in patients with chronic kidney disease undergoing hemodialysis, and have been recognized as key outcome predictors. This review attempts to summarize recent evidence pointing to the usefulness of the method in the detection of clinical and subclinical cardiac dysfunction, stratification of cardiovascular risk and assessment of intervention strategies.

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Section: Left Ventricular Systolic Dysfunctionmentioning

confidence: 99%

Alterações ecocardiográficas em pacientes com insuficiência renal crônica em programa de hemodiálise

Barberato

Pécoits-Filho

2010

Arq. Bras. Cardiol.

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“…LVH is an adaptive response to chronic pressure and volume overload. Chronic overload in combination with metabolic, electrolytic, and hormonal changes leads to maladaptive LVH characterized by structural changes in the myocardium, resulting in systolic and diastolic dysfunction [3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Global left-ventricular function by tissue Doppler imaging in pediatric dialysis patients

et al. 2008

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Cardiovascular abnormalities are observed in most children with end-stage renal disease (ESRD). The aim of this study was evaluation of left-ventricular (LV) myocardial performance using tissue-Doppler imaging (TDI) in patients with ESRD. Twenty-five patients with ESRD and 25 healthy gender- and age-matched control subjects were assessed with conventional M-mode echocardiography, pulsed-wave Doppler (PWD), and TDI. Myocardial Performance Index (MPI) and LV mass index (LVMI) were calculated. MPI and conventional echo-Doppler indices were compared in the ESRD and control groups. Significant differences were present in the mean systolic and diastolic blood pressure (BP) between children with ESRD and healthy children (p = 0.007 and p < 0.001, respectively). The mean LVMI was significantly greater in the patient group (p < 0.001). The tissue-Doppler MPI of patients was significantly higher than that in healthy children (p < 0.001). LVMI was significantly correlated with systolic and diastolic BP. MPI obtained by TDI was significantly correlated with LVMI. Our study confirms that LV dysfunction is present in patients with ESRD and hypertension is an important risk factor.

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“…Cardiovascular structure and functions are affected by volume and pressure overload, anemia and uremic ‘toxic’ environment in end-stage renal failure [1]. Cyclic variations of extracelluler fluid volume in hemodialysis patients change the cardiovascular hemodynamics and humoral factors [2].…”

Section: Introductionmentioning

confidence: 99%

Use of Tissue Doppler to Assess Right Ventricle Function in Hemodialysis Patients

Arınç¹,

Gunduz²,

Tamer

et al. 2005

Am J Nephrol

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Aims: Although there are plenty of data about the differences in left ventricular tissue Doppler (TD) velocities by preload reduction, only a few studies regarding right ventricular function are found in the literature. We investigated the effect of intravascular volume reduction on right ventricular function by ultrafiltration in dialysis patients. Methods: 27 end-stage renal failure patients who were hypervolemic and undergoing hemodialysis were included in the study. TD studies of the right ventricle were performed before and 1 h after dialysis. These data were compared. Results: The mean age of the patients was 41 ± 15 years and mean volume of ultrafiltration was 3.8 ± 1.8 liters. Systolic, early and late diastolic lateral annular TD velocities before dialysis were 0.109 ± 0.029, 0.088 ± 0.039, 0.111 ± 0.039 m/s, and after dialysis were 0.099 ± 0.028, 0.078 ± 0.036, 0.106 ± 0.037 m/s, respectively (p = 0.216, p = 0.112, p = 0.350). Myocardial early diastolic velocity decreased significantly (p = 0.049) but systolic and late diastolic velocities did not change significantly (p = 0.579, p = 0.146). Conclusion: Right ventricular systolic and diastolic velocities detected by TD were not or only minimally affected by preload reduction in hemodialysis patients and the TD early/late ratio is the most valuable variable that can predict right ventricular diastolic function. The right ventricular systolic and early diastolic TD velocities were positively correlated with left ventricle ejection fraction.

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Disorders of left ventricular structure and function in chronic uremia: how often, why and what to do with it?

Cited by 24 publications

References 76 publications

Alterações ecocardiográficas em pacientes com insuficiência renal crônica em programa de hemodiálise

Alterações ecocardiográficas em pacientes com insuficiência renal crônica em programa de hemodiálise

Global left-ventricular function by tissue Doppler imaging in pediatric dialysis patients

Use of Tissue Doppler to Assess Right Ventricle Function in Hemodialysis Patients

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