Disinfection measures and control of SARS-COV-2 transmission

Duarte, Phelipe Magalhães; Santana, Vivian Tallita Pinheiro de

doi:10.31646/gbio.64

Cited by 28 publications

(17 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…High reactiveness and no toxicity associated with the chlorinated system is advantageous to use this system. Chemical solutions like povidone‑iodine (>0.23%), formaldehyde (>0.7%), isopropanol (>70%), and ethyl alcohol (>75%) can also inactivate SARS-CoV-2 ( Duarte and Santana, 2020 ).…”

Section: Disinfection and Reprocessing Techniquesmentioning

confidence: 99%

Disinfection technology and strategies for COVID-19 hospital and bio-medical waste management

Ilyas

Srivastava

2020

Science of The Total Environment

346

259

View full text Add to dashboard Cite

The isolation wards, institutional quarantine centers, and home quarantine are generating a huge amount of bio-medical waste (BMW) worldwide since the outbreak of novel coronavirus disease-2019 (COVID-19). The personal protective equipment, testing kits, surgical facemasks, and nitrile gloves are the major contributors to waste volume. Discharge of a new category of BMW (COVID-waste) is of great global concern to public health and environmental sustainability if handled inappropriately. It may cause exponential spreading of this fatal disease as waste acts as a vector for SARS-CoV-2, which survives up to 7 days on COVID-waste (like facemasks). Proper disposal of COVID-waste is therefore immediately requires to lower the threat of pandemic spread and for sustainable management of the environmental hazards. Henceforth, in the present article, disinfection technologies for handling COVID-waste from its separate collection to various physical and chemical treatment steps have been reviewed. Furthermore, policy briefs on the global initiatives for COVID-waste management including the applications of different disinfection techniques have also been discussed with some potential examples effectively applied to reduce both health and environmental risks. This article can be of great significance to the strategy development for preventing/controlling the pandemic of similar episodes in the future.

show abstract

Section: Disinfection and Reprocessing Techniquesmentioning

confidence: 99%

Disinfection technology and strategies for COVID-19 hospital and bio-medical waste management

Ilyas

Srivastava

2020

Science of The Total Environment

346

259

View full text Add to dashboard Cite

show abstract

“…Our heatmap demonstrates the efficacy of standard chemical techniques in decontaminating surfaces exposed to SARS-CoV-2 in a hospital setting. The literature has also described alternative methods for SARS-CoV-2 elimination, including high-intensity ultraviolet light, ozone gas, and other decontamination agents for surface, droplet-borne, and aerosolized SARS-CoV-2 [ 22 , 23 , 24 , 25 ]. However, research is only now beginning to emerge with regard to their application as a widespread, standardized replacement for current chemical methods and should continue to be investigated [ 26 ].…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of SARS-CoV-2 Decontamination and Containment in a COVID-19 ICU

Brune

Kuschner

Mootz

et al. 2021

IJERPH

View full text Add to dashboard Cite

Background: Health care systems in the United States are continuously expanding and contracting spaces to treat patients with coronavirus disease 2019 (COVID-19) in intensive care units (ICUs). As a result, hospitals must effectively decontaminate and contain severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in constructed and deconstructed ICUs that care for patients with COVID-19. We assessed decontamination of a COVID-19 ICU and examined the containment efficacy of combined contact and droplet precautions in creating and maintaining a SARS-CoV-2–negative ICU “antechamber”. Methods: To examine the efficacy of chemical decontamination, we used high-density, semi-quantitative environmental sampling to detect SARS-CoV-2 on surfaces in a COVID-19 ICU and COVID-19 ICU antechamber. Quantitative real-time polymerase chain reaction was used to measure viral RNA on surfaces. Viral location mapping revealed the distribution of viral RNA in the COVID-19 ICU and COVID-19 ICU antechamber. Results were further assessed using loop-mediated isothermal amplification. Results: We collected 224 surface samples pre-decontamination and 193 samples post-decontamination from a COVID-19 ICU and adjoining COVID-19 ICU antechamber. We found that 46% of antechamber objects were positive for SARS-CoV-2 pre-decontamination despite the construction of a swinging door barrier system, implementation of contact precautions, and installation of high-efficiency particulate air filters. The object positivity rate reduced to 32.1% and viral particle rate reduced by 95.4% following decontamination. Matched items had an average of 432.2 ± 2729 viral copies/cm2 pre-decontamination and 19.2 ± 118 viral copies/cm2 post-decontamination, demonstrating significantly reduced viral surface distribution (p < 0.0001). Conclusions: Environmental sampling is an effective method for evaluating decontamination protocols and validating measures used to contain SARS-CoV-2 viral particles. While chemical decontamination effectively removes detectable viral RNA from surfaces, our approach to droplet/contact containment with an antechamber was not highly effective. These data suggest that hospitals should plan for the potential of aerosolized virions when creating strategies to contain SARS-CoV-2.

show abstract

“…As with several other emerging or recurring diseases that are transmitted by aerosols or droplets, it is important to adopt good hygiene practices, like washing hands with soap and water for at least twenty seconds and then using 70% alcohol gel. Furthermore, it is effective to practice social distancing as a preventive measure, avoiding both large crowds and contact with people who may be infected [ 114 , 115 ]. Data on COVID-19, SARS, and MERS provided evidence that the policy of physical distance of at least 1 m may not be sufficient—2 m may be more effective.…”

Section: Sars-cov-2 Protection Strategymentioning

confidence: 99%

SARS-CoV-2: Outline, Prevention, and Decontamination

et al. 2021

View full text Add to dashboard Cite

The new coronavirus began to spread around the world in late 2019. Initially, it was found only in China, but in the following days there were reported cases of infections in other countries. Subsequently, based on taxonomy, phylogeny, and accepted practice, the virus was officially designated as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). As a result of the rapid spread of SARS-CoV-2 in different countries around the world, on March 11, 2020, the World Health Organization (WHO) announced a status change in the disease caused by this coronavirus—from an epidemic to a pandemic disease. Although the world is taking unprecedented efforts to control the spread of SARS-CoV-2, the number of confirmed cases is rising. Therefore, effective preventive measures are needed in order to limit the spread of illness. The prevention measures are mainly based on information on the virus transmission routes, its environmental stability, and persistence on commonly touched surfaces. Social distancing, mask usage, and good hygiene practice are the most important recommendations for general public. Healthcare professionals who are directly involved in SARS-CoV-2 patients care are more exposed to virus infection and additional protection measures are necessary, including protective suits, aprons, face shields, goggles, and gloves. Due to the stability of SARS-CoV-2 on different surfaces, such as glass, paper, or wood, proper disinfection is crucial. Several studies have shown that despite the virus’s stability, it is sensitive to various disinfectants, such as ethanol, isopropanol, sodium hypochlorite, or hydrogen peroxide. These findings underline the importance of having comprehensive knowledge about SARS-CoV-2 and multidirectional strategies in order to limit the spread of the virus. This review is a summary of the most important information about SARS-CoV-2, such as its stability on different surfaces, protection strategies, and decontamination options.

show abstract

Disinfection measures and control of SARS-COV-2 transmission

Cited by 28 publications

References 11 publications

Disinfection technology and strategies for COVID-19 hospital and bio-medical waste management

Disinfection technology and strategies for COVID-19 hospital and bio-medical waste management

Effectiveness of SARS-CoV-2 Decontamination and Containment in a COVID-19 ICU

SARS-CoV-2: Outline, Prevention, and Decontamination

Contact Info

Product

Resources

About