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Jc, Semenza

doi:10.1016/s0749-3797(99)00066-5

Cited by 26 publications

(10 citation statements)

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“…Additionally, excess admissions for renal diseases occurred even with increases in moderate heat. Positive associations between temperature, heat events, and admissions for renal diseases have been reported in several other studies in the United States and elsewhere (Fletcher et al 2012; Green et al 2010; Hansen et al 2008; Knowlton et al 2009; Kovats et al 2004; Mastrangelo et al 2006, 2007; Nitschke et al 2007, 2011; Semenza 1999; Wang et al 2012). Renal admissions increased 8% (95% CI: 5%, 12%) among individuals 65–84 years of age in New York State for a 2.8°C increase in mean temperature (Fletcher et al 2012).…”

Section: Discussionsupporting

confidence: 61%

“…During the 2006 heat wave in California, renal admissions increased 4% (95% CI: 1%, 7%) (Knowlton et al 2009). During the 1995 heat wave in Chicago, renal admissions increased by 109% (95% CI: 84%, 140%) (Semenza 1999). This body of evidence suggests a need to target patients with renal conditions for additional protective measures during hot weather in cities across the United States, although individuals with previously identified renal conditions may not account for the entire increase in renal admissions associated with heat.…”

Section: Discussionmentioning

confidence: 99%

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Heat, Heat Waves, and Hospital Admissions among the Elderly in the United States, 1992–2006

Gronlund

Zanobetti²,

Schwartz³

et al. 2014

Environ Health Perspect

234

159

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Background: Heat-wave frequency, intensity, and duration are increasing with global climate change. The association between heat and mortality in the elderly is well documented, but less is known regarding associations with hospital admissions.Objectives: Our goal was to determine associations between moderate and extreme heat, heat waves, and hospital admissions for nonaccidental causes among Medicare beneficiaries ≥ 65 years of age in 114 cities across five U.S. climate zones.Methods: We used Medicare inpatient billing records and city-specific data on temperature, humidity, and ozone from 1992 through 2006 in a time-stratified case-crossover design to estimate the association between hospitalization and moderate [90th percentile of apparent temperature (AT)] and extreme (99th percentile of AT) heat and heat waves (AT above the 95th percentile over 2–8 days). In sensitivity analyses, we additionally considered confounding by ozone and holidays, different temperature metrics, and alternate models of the exposure–response relationship.Results: Associations between moderate heat and hospital admissions were minimal, but extreme heat was associated with a 3% (95% CI: 2%, 4%) increase in all-cause hospital admissions over the subsequent 8 days. In cause-specific analyses, extreme heat was associated with increased hospitalizations for renal (15%; 95% CI: 9%, 21%) and respiratory (4%; 95% CI: 2%, 7%) diseases, but not for cardiovascular diseases. An added heat-wave effect was observed for renal and respiratory admissions.Conclusion: Extreme heat is associated with increased hospital admissions, particularly for renal causes, among the elderly in the United States.Citation: Gronlund CJ, Zanobetti A, Schwartz JD, Wellenius GA, O’Neill MS. 2014. Heat, heat waves, and hospital admissions among the elderly in the United States, 1992–2006. Environ Health Perspect 122:1187–1192; http://dx.doi.org/10.1289/ehp.1206132

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Section: Discussionsupporting

confidence: 61%

Section: Discussionmentioning

confidence: 99%

Heat, Heat Waves, and Hospital Admissions among the Elderly in the United States, 1992–2006

Gronlund

Zanobetti²,

Schwartz³

et al. 2014

Environ Health Perspect

234

159

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“…8 Heat waves and related dehydration are associated with both acute renal failure and chronic renal disease. 2 , 4 , 9 – 11 …”

Section: Introductionmentioning

confidence: 99%

Association Between Occupational Heat Stress and Kidney Disease Among 37 816 Workers in the Thai Cohort Study (TCS)

Tawatsupa

Lim

Kjellström

et al. 2012

Journal of Epidemiology

106

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BackgroundWe examined the relationship between self-reported occupational heat stress and incidence of self-reported doctor-diagnosed kidney disease in Thai workers.MethodsData were derived from baseline (2005) and follow-up (2009) self-report questionnaires from a large national Thai Cohort Study (TCS). Analysis was restricted to full-time workers (n = 17 402 men and 20 414 women) without known kidney disease at baseline. We used logistic regression models to examine the association of incident kidney disease with heat stress at work, after adjustment for smoking, alcohol drinking, body mass index, and a large number of socioeconomic and demographic characteristics.ResultsExposure to heat stress was more common in men than in women (22% vs 15%). A significant association between heat stress and incident kidney disease was observed in men (adjusted odds ratio [OR] = 1.48, 95% CI: 1.01–2.16). The risk of kidney disease was higher among workers reporting workplace heat stress in both 2005 and 2009. Among men exposed to prolonged heat stress, the odds of developing kidney disease was 2.22 times that of men without such exposure (95% CI 1.48–3.35, P-trend <0.001). The incidence of kidney disease was even higher among men aged 35 years or older in a physical job: 2.2% exposed to prolonged heat stress developed kidney disease compared with 0.4% with no heat exposure (adjusted OR = 5.30, 95% CI 1.17–24.13).ConclusionsThere is an association between self-reported occupational heat stress and self-reported doctor-diagnosed kidney disease in Thailand. The results indicate a need for occupational health interventions for heat stress among workers in tropical climates.

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“…Hospital admissions during heat waves have been reported to increase among both older and younger adults, especially among adults living in institutions or engaging in outdoor activities involving exertion (Johnson et al 2005; Kovats and Ebi 2006). Most admissions were for heat-related conditions, including heat exhaustion and heat stroke, dehydration and electrolyte disorders, and acute renal failure (Kovats and Ebi 2006; Mastrangelo et al 2006; Semenza 1999; Semenza et al 1999). Some increases in admissions for neurologic conditions and mental illnesses (Kovats and Ebi 2006) and ambulance transport for violence-related causes (Nitschke et al 2007) have been reported.…”

mentioning

confidence: 99%

The 2006 California Heat Wave: Impacts on Hospitalizations and Emergency Department Visits

Knowlton

Rotkin-Ellman

King

et al. 2009

Environ Health Perspect

635

515

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BackgroundClimate models project that heat waves will increase in frequency and severity. Despite many studies of mortality from heat waves, few studies have examined morbidity.ObjectivesIn this study we investigated whether any age or race/ethnicity groups experienced increased hospitalizations and emergency department (ED) visits overall or for selected illnesses during the 2006 California heat wave.MethodsWe aggregated county-level hospitalizations and ED visits for all causes and for 10 cause groups into six geographic regions of California. We calculated excess morbidity and rate ratios (RRs) during the heat wave (15 July to 1 August 2006) and compared these data with those of a reference period (8–14 July and 12–22 August 2006).ResultsDuring the heat wave, 16,166 excess ED visits and 1,182 excess hospitalizations occurred statewide. ED visits for heat-related causes increased across the state [RR = 6.30; 95% confidence interval (CI), 5.67–7.01], especially in the Central Coast region, which includes San Francisco. Children (0–4 years of age) and the elderly (≥ 65 years of age) were at greatest risk. ED visits also showed significant increases for acute renal failure, cardiovascular diseases, diabetes, electrolyte imbalance, and nephritis. We observed significantly elevated RRs for hospitalizations for heat-related illnesses (RR = 10.15; 95% CI, 7.79–13.43), acute renal failure, electrolyte imbalance, and nephritis.ConclusionsThe 2006 California heat wave had a substantial effect on morbidity, including regions with relatively modest temperatures. This suggests that population acclimatization and adaptive capacity influenced risk. By better understanding these impacts and population vulnerabilities, local communities can improve heat wave preparedness to cope with a globally warming future.

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Cited by 26 publications

References 0 publications

Heat, Heat Waves, and Hospital Admissions among the Elderly in the United States, 1992–2006

Heat, Heat Waves, and Hospital Admissions among the Elderly in the United States, 1992–2006

Association Between Occupational Heat Stress and Kidney Disease Among 37 816 Workers in the Thai Cohort Study (TCS)

The 2006 California Heat Wave: Impacts on Hospitalizations and Emergency Department Visits

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