Discriminatory Ability of Visceral Adiposity Index (VAI) in Diagnosis of Metabolic Syndrome: A Population Based Study

Abstract

Visceral adiposity index (VAI) has been suggested as an index of visceral adiposity. This study was conducted to determine the discriminatory ability of VAI in diagnosis of metabolic syndrome (MetS). We used the data of 5 312 subjects aged 18-74 years of a cohort study conducted among 6 140 individuals aged 10-90 years in Amol, northern Iran. The city population was divided into 16 strata based on gender and age groups in 10-year intervals. The subjects were randomly selected from each stratum. MetS was defined based on National Cholesterol Education Program Adult Treatment Panel III (NCEP/ATPIII), American Heart Association/National Heart, Lung and Blood Institute (AHA/NHLBI) update of Adult Treatment Panel III (ATPIII), International Diabetes Federation (IDF) and joint interim statement (JIS) definitions. The discriminatory ability of VAI and other obesity measures were evaluated using receiver operating characteristic (ROC) curves. While waist circumference (WC) showed the highest discriminatory ability for MetS in IDF definition in men (AUC=0.899 [CI=0.888-0.910]), VAI had the greatest discriminatory ability according to other definitions in men and women. The related AUCs of VAI were 0.866 (95%CI: 0.850-0.881), 0.829 (95%CI: 0.813-0.846), 0.859 (95%CI: 0.844-0.873) and 0.876 (95%CI: 0.863-0.889) based on NCEP/ATPIII, AHA/NHLBI update of ATPIII, IDF and JIS definition in men, and also 0.888 (95%CI: 0.875-0.902), 0.894 (95%CI: 0.881-0.907), 0.883 (95%CI: 0.869-0.897) and 0.879 (95%CI: 0.864-0.894) in women, respectively. VAI showed an excellent discriminatory ability in diagnosis of MetS. Considering its relatively simple calculation, this index could be suggested as a reliable tool in medical practice.

Visceral adiposity index and overactive bladder in postmenopausal woman: A novel predictive risk factor

“…VAI is a reliable marker of central obesity. Our results supports findings of previously reported studies (13). Patients with high VAI levels have increases OAB symptoms, in terms of urgency and urge incontinence.…”

“…BMI over 30 reported as an independent risk factor for OAB and DOA in some studies (13)(14)(15)(16). In a study relationship between central and general obesity in terms of OAB and incontinance eavulated.…”

<p>Incidence and Predictors of Tuberculosis among Adult Diabetic Patients, Debre Markos Referral Hospital, Northwest Ethiopia, 2018: A Retrospective Cohort Study</p>

“…Accordingly, it is estimated that about 1.6 million deaths were directly caused by DM -which is 1.69 times more likely to develop into TB than among non-DM individualsin 2015. 5,6 Currently, the worldwide prevalence of DM is increasing more quickly than ever (11.7%), which increases TB and makes existing treatments very complex among the coinfected patients. 7 The prevalence of DM and the incidence of TB in Ethiopia have been found to be 6.5% and 164 per 100,000 population, respectively.…”

Positively increased visceral adiposity index in hyperuricemia free of metabolic syndrome

“…There are two kinds of central obesity: subcutaneous and visceral fat mass, and waist circumference (WC) alone does not help distinguishing them [ 1 ]. The Visceral Adiposity Index (VAI), which is based on WC, body mass index (BMI), triglycerides(TG), and high density lipoprotein cholesterol (HDL-C) and was recently introduced by Amato et al [ 2 ], was used as a marker of visceral fat dysfunction, and been suggested as an indicator of Metabolic syndrome (MetS) [ 3 , 4 ]. MetS, which was defined as a distinct entity which comprises the following components: central obesity, dyslipidemia, hyperglycemia and hypertension, increase a person’s risk of cardiovascular disease [ 5 , 6 ], and more and more studies revealed that hyperuricemia is a risk factor of MetS [ 7 – 9 ].…”