&lt;p&gt;Incidence and Predictors of Tuberculosis among Adult Diabetic Patients, Debre Markos Referral Hospital, Northwest Ethiopia, 2018: A Retrospective Cohort Study&lt;/p&gt;

Gedfew, Mihretie; Ayana, Mulatu; Abate, Abebe; Bewket, Bekalu; Haile, Dessalegn; Edmealem, Afework; Andualem, Atsedemariam

doi:10.2147/dmso.s233564

Cited by 2 publications

(1 citation statement)

References 25 publications

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“…Similar findings were observed in a study conducted in Southern zone Tigray, Ethiopia, [10] and at Debre Markos referral hospital, Northwest Ethiopia among HIV-infected children on ART. [19] In our study, bivariate analysis shows that good adherence to ART protects PLWHIV from developing OIs, which corroborates other studies whereby poor adherence remains quite a negative factor. [7,9,20] According to multivariable analysis in this study, age had no effect on developing OIs, unlike in other studies conducted among PLWHIV on ART in Southern Ethiopia, whereby, OIs were found to be associated with being aged 35 years or above.…”

Section: Discussionsupporting

confidence: 91%

Opportunistic Infections and Associated Factors among HIV-Infected Adult Persons on Antiretroviral Therapy at Ruhengeri Referral Hospital, Rwanda: A cross-sectional study

Itanga¹,

Ndagijimana²,

Simbi³

et al. 2022

Rwanda J Med Health Sci

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Background Human Immunodeficiency Virus (HIV) is among the highest health crises that humanity ever confronted and it causes progressive weakening of the immune system leading to opportunistic infections (OIs) or malignancies during the natural course of the disease. This study aimed at assessing the prevalence and factors associated with the occurrence of OIs among adult PLWHIV on antiretroviral therapy (ART) at Ruhengeri referral hospital. Methodology A cross-sectional study was performed by reviewing records of HIV-positive adult (≥ 15 years) on ART enrolled at Ruhengeri referral hospital from 1st January 2007 to 31st December 2017. Opportunistic infections were reported based on clinical diagnosis and the prevalence of OIs was determined. Results The study reviewed records from 423 PLWHIV. Thirty-nine (9.2%) PLWHIV had been diagnosed with OIs; and frequent OIs were tuberculosis (20%), oral candidiasis, pneumonia and STI (15.6% each). The independent risk factors for developing OIs were being jobless (AOR = 5.03, 95% CI = 2.13, 32.99), spending more than five years on ART (AOR = 4.34, 95% CI = 1.12-16.78) and starting ART at WHO clinical stage III (AOR = 4.88, 95% CI = 1.65-16.78). Conclusion There is a need to strengthen the management of opportunistic infections despite the use of ART at Ruhengeri referral hospital. Rwanda J Med Health Sci 2022;5(3):323-331

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