Discrimination of the Traditional Chinese Medicine from Schisandra Fruits by Flash Evaporation-Gas Chromatography/Mass Spectrometry and Fingerprint Analysis

Huang, Zhongping; Huang, Yilei; Xu, Shaonan; Dong, Wenxia; Pan, Zaifa; Wang, Lili

doi:10.1007/s10337-015-2917-8

Cited by 15 publications

(8 citation statements)

References 16 publications

(21 reference statements)

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“…Using fingerprint could reflect integral characterization of herbal drugs and offer the possibility for TCM quality control in a holistic manner, which is consistent with the principle of traditional Chinese medicine [67]. [69]. Since techniques in fingerprint establishment are becoming more and more mature and easily assessable, inclusion of fingerprint in pharmacopoeia monographs would be more and more often and necessary for better quality control of herbal drugs.…”

Section: Fingerprintmentioning

confidence: 73%

“…Lu et al established HPLC fingerprint coupled with similarity, hierarchical clustering, and principal component analyses to evaluate the quality of raw and processed Corydalis Rhizoma from different origins [ 68 ]. Huang et al used GC–MS fingerprint combined with chemometric approaches for the discrimination of Schisandrae Fructus from different species and different growing places [ 69 ]. Since techniques in fingerprint establishment are becoming more and more mature and easily assessable, inclusion of fingerprint in pharmacopoeia monographs would be more and more often and necessary for better quality control of herbal drugs.…”

Section: Advanced Analytical Techniques For Quality Standard Of Tcmmentioning

confidence: 99%

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Quality standard of traditional Chinese medicines: comparison between European Pharmacopoeia and Chinese Pharmacopoeia and recent advances

et al. 2020

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Traditional Chinese medicine (TCM) are becoming more and more popular all over the world. However, quality issues of TCM may lead to medical incidents in practice and therefore quality control is essential to TCM. In this review, the state of TCM in European Pharmacopoeia are compared with that in Chinese Pharmacopoeia, and herbal drugs that are not considered as TCM and not elaborated by TCM working party at European Directorate for the Quality of Medicines & Health Care (EDQM) but present in both European Pharmacopoeia and Chinese Pharmacopoeias are also discussed. Different aspects in quality control of TCM including origins, identification, tests and assays, as well as sample preparation, marker selection and TCM processing are covered to address the importance of establishing comprehensive quality standard of TCM. Furthermore, advanced analytical techniques for quality control and standard establishment of TCM are also reviewed. Electronic supplementary material The online version of this article (10.1186/s13020-020-00357-3) contains supplementary material, which is available to authorized users.

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Section: Fingerprintmentioning

confidence: 73%

Section: Advanced Analytical Techniques For Quality Standard Of Tcmmentioning

confidence: 99%

Quality standard of traditional Chinese medicines: comparison between European Pharmacopoeia and Chinese Pharmacopoeia and recent advances

et al. 2020

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“…For example, thin-layer chromatography is easy to operate, but it has low accuracy for TCMs from a same genus because they share many similar compositions [5]. Phytochemistry requires a large amount of samples and requires expensive equipment such as chromatographs [6][7][8]. In recent years, molecular biology technology (DNA barcode technology) has also been applied in the identification of TCMs [9][10][11].…”

Section: Introductionmentioning

confidence: 99%

The Application of Electrochemical Oscillation Methods for Identification of Traditional Chinese Medicine Materials

Shi

Zheng

2022

Applied Sciences

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Electrochemical oscillation reflects the overall characteristics of the system under test in terms of redox activity. It has proven to be advantageous in analyzing and processing complex components of herbal systems, such as polysaccharides and proteins. Therefore, it is widely used in the quantitative or qualitative tests of traditional Chinese medicines (TCMs) for identification and quality control. Electrochemical oscillation has several advantages such as high sensitivity, stability and micro sample requirement. Compared with other traditional methods, the interaction of multi-component in the TCMs was taken into account, which provides new ideas for the search of TCMs. Here, we presented a brief introduction on the progress on the topic, which promoted the development of electrochemical oscillation and the standardization of TCMs in the last twenty years. Electrochemical oscillation method is cheap, sensitive, fast, stable and convenient for the identification and quality control of TCMs. Reaction systems and the visualization of the fingerprints can be improved in the future.

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“…To ensure the reliability and repeatability of pharmacological research, to understand the bioactivities of medicines, and to enhance product quality control, the whole profiles of herbal medicines need to be determined . Currently, modern chemical, physical, and biological analysis methods are used as common fingerprinting methods in TCM, such as thin‐layer chromatography (TLC), high‐performance liquid chromatography (HPLC), high‐speed counter‐current chromatography (HSCCC), gas chromatography (GC), ultraviolet spectroscopy (UV), Fourier transform infrared spectroscopy (FTIR), near infrared spectroscopy (NIR), mass spectroscopy (MS), nuclear magnetic resonance spectroscopy (NMR), X‐ray diffraction, capillary electrophoresis (CE), and DNA techniques …”

Section: Introductionmentioning

confidence: 99%

Geographic origin identification and rapid determination of four constituents of Gentiana rigescens by FTIR combined with chemometrics

Zhao

Tianjun

Zhang

et al. 2019

Journal of Chemometrics

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Gentiana rigescens is one of the most important traditional Chinese medicines because of its therapeutic effects in protecting the liver and promoting bile discharge, anti‐hypertension, and spasm and pain relief. To enhance quality control, a comprehensive assessment of G. rigescens from different geographic origins by Fourier‐transform infrared (FTIR) in combination with chemometrics was conducted. Through pretreatment by the second derivative, spectrum standard deviation and Monte Carlo uninformative variable elimination (MC‐UVE), the characteristic FTIR spectra were selected and an identification model of the different geographic origins of G. rigescens was built by partial least squares discriminant analysis (PLS‐DA). The validation results showed that the accuracy rates of the model were 100%, 97.22%, and 100% for samples from Yunnan, Guizhou, and Sichuan, respectively. On the basis of the correlation between characteristic spectral points and the contents of swertiamarin, gentiopicroside, sweroside, and loganic acid, quantitative models were established by partial least squares regression (PLSR). The measured and predicted values were not significantly different as assessed through the paired t test (p > 0.05). Additionally, the characteristic spectra were interpreted, and 93 common peaks were selected. FTIR analysis combined with chemometric methods could accurately identify the different geographic origins of G. rigescens and rapidly predict the content of swertiamarin, gentiopicroside, sweroside, and loganic acid, thus providing a comprehensive method of evaluating traditional Chinese medicines.

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Discrimination of the Traditional Chinese Medicine from Schisandra Fruits by Flash Evaporation-Gas Chromatography/Mass Spectrometry and Fingerprint Analysis

Abstract: simple, rapid, and effective method for the origin discrimination and quality control of Schisandra fruits.

Cited by 15 publications

References 16 publications

Quality standard of traditional Chinese medicines: comparison between European Pharmacopoeia and Chinese Pharmacopoeia and recent advances

Quality standard of traditional Chinese medicines: comparison between European Pharmacopoeia and Chinese Pharmacopoeia and recent advances

The Application of Electrochemical Oscillation Methods for Identification of Traditional Chinese Medicine Materials

Geographic origin identification and rapid determination of four constituents of Gentiana rigescens by FTIR combined with chemometrics

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