Discovery of Anti-Inflammatory Triterpenoid Glucosides from the Heritiera littoralis Dryand

Liang, Xiaoqin; Niu, Peng; Li, Jun; Guan, Xin-Lan; Zhang, Yanjun; Li, Jian

doi:10.3390/molecules28041658

Cited by 2 publications

(1 citation statement)

References 32 publications

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“…Prior research has indicated that the diversity of the H. littoralis community decreases from the coast of adjacent seas to the marsh of inland seas [43]. Based on the distribution map of H. littoralis we have generated, the suitability index is higher closer to the sea area, which is consistent with the general suitability of mangrove plants.…”

Section: Ecologically Suitable Areas In Chinasupporting

confidence: 76%

Potential Distribution Areas Prediction of Endangered Species - <i>Heritiera littoralis</i> Based on MaxEnt Modeling in China

Wang,

Liu,

Cheng

et al. 2024

Pol. J. Environ. Stud.

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The endangered semi-mangrove plant Heritiera littoralis occupies an overall area of less than 30 hm 2 in China. In this study, we employed the MaxEnt model to predict the distribution patterns of H. littoralis during the Last Glaciation Maximum, the present day, and the future. Drawing from 41 distributed records and 12 environmental factors within China, we investigated the species' potential habitats. To anticipate future scenarios, we assessed its distribution under the RCP4.5 greenhouse gas emission scenario for 2050 and 2070. As a result, four primary distribution areas emerged in Guangxi, Guangdong, Hainan, and Taiwan, signifying the main potential habitats for H. littoralis. Our findings indicate that the distribution centre of H. littoralis remains in Guangxi across the four time periods, with a projected eastward migration. By 2050, the species' habitat range is anticipated to contract, whereas, by 2070, the suitable habitat area is expected to expand. Moreover, we identify pivotal environmental factors influencing the potential distribution of H. littoralis, including precipitation of the warmest quarter (Bio 18), temperature seasonality (Bio 4), mean diurnal range (Bio 2), precipitation of the wettest month (Bio 13), and annual mean temperature (Bio 1). The outcomes of this study offer valuable data for comprehending the distribution of H. littoralis in China. Furthermore, they aid in pinpointing areas suitable for conservation management, both presently and in the future.

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Section: Ecologically Suitable Areas In Chinasupporting

confidence: 76%

Potential Distribution Areas Prediction of Endangered Species - <i>Heritiera littoralis</i> Based on MaxEnt Modeling in China

Wang,

Liu,

Cheng

et al. 2024

Pol. J. Environ. Stud.

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Triterpenoids from the Leaves of Cyclocarya paliurus and Their Glucose Uptake Activity in 3T3-L1 Adipocytes

et al. 2023

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Four new dammarane triterpenoid saponins cypaliurusides Z1–Z4 (1–4) and eight known analogs (5–12) were isolated from the leaves of Cyclocarya paliurus. The structures of the isolated compounds were determined using a comprehensive analysis of 1D and 2D NMR and HRESIMS data. The docking study demonstrated that compound 10 strongly bonded with PTP1B (a potential drug target for the treatment of type-II diabetes and obesity), hydrogen bonds, and hydrophobic interactions, verifying the importance of sugar unit. The effects of the isolates on insulin-stimulated glucose uptake in 3T3-L1 adipocytes were evaluated and three dammarane triterpenoid saponins (6, 7 and 10) were found to enhance insulin-stimulated glucose uptake in 3T3-L1 adipocytes. Furthermore, compounds 6, 7, and 10 exhibited potent abilities to promote insulin-stimulated glucose uptake in 3T3-L1 adipocytes in a dose-dependent manner. Thus, the abundant dammarane triterpenoid saponins from C. paliurus leaves exhibited stimulatory effects on glucose uptake with application potential as a antidiabetic treatment.

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Discovery of Anti-Inflammatory Triterpenoid Glucosides from the Heritiera littoralis Dryand

Cited by 2 publications

References 32 publications

Potential Distribution Areas Prediction of Endangered Species - <i>Heritiera littoralis</i> Based on MaxEnt Modeling in China

Potential Distribution Areas Prediction of Endangered Species - <i>Heritiera littoralis</i> Based on MaxEnt Modeling in China

Triterpenoids from the Leaves of Cyclocarya paliurus and Their Glucose Uptake Activity in 3T3-L1 Adipocytes

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