Disc Electrophoresis of Globulin Fractions of Aqueous Humour in Patients with Retinal Detachment

Abstract

Aqueous humour and serum taken from 24 patients with retinal detachment have been examined using the technique of disc electrophoresis on polyacrylamide gel. An evaluation of four groups of globulin fractions (post-albumins, transferrin, polyglobulin and macroglobulin) has been made in persentages of the total number of globulins. Significant differences were found in the 4 aqueous humour globulin fractions as compared to the same fractions of the serum. Patients with retinal detachment due to inflammation were characterized by the higher level of the post-albumin fraction and lower level of the transferrin fraction in the aqueous humour, whereas in traumatic cases and in aphakia the conditions were just the opposite. With the duration of the disease, the level of the polyglobulin fraction was enhanced both in the aqueous humour and in the serum.