Direct‐To‐Consumer Advertising of Over‐the‐Counter Sinonasal Remedies: A History of Mixed Messages

McCoul, Edward D.

doi:10.1002/lary.28366

Cited by 7 publications

(4 citation statements)

References 13 publications

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“…OTC drugs are characterized by their use for a short period of time, for a proven indication and with a low risk potential for the patient; medicines related to the digestive system alone were worth $ 4.3 billion in the United States in 2016 [ 4 ]. However, there are few studies on the use of OTCs by the general population; little is known about prescription profiles, usage patterns, concomitant medications and proportion of inappropriate use.…”

Section: Introductionmentioning

confidence: 99%

Proton pump inhibitor and community pharmacies: Usage profile and factors associated with long-term use

et al. 2021

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Aim To characterize the usage profile and the factors associated with the prolonged use of proton pump inhibitor drugs in a community pharmacy. Methodology This is a cross-sectional, prospective and observational study involving interviews with 410 patients who acquired PPI for their own use from community pharmacies. To characterize the factors associated with the prolonged use of PPI, a multivariate logistic regression model was used. Results Pantoprazole (42.7%) and omeprazole (31%) were the most acquired PPIs, prescribed mainly by gastroenterologists (49.5%). They are used in the morning, especially for gastrointestinal symptoms, however, they had been consumed for more than 5 years in 30% of cases. The factors associated with prolonged use are old age (OR 1.03 CI95% 1.01–1.05), body mass index (OR 1.07 CI95% 1.01–1.12), use of non-steroidal anti-inflammatories (OR 3.18 CI95% 1.20–8.43) and selective serotonin reuptake inhibitors (OR 3.5 95% CI 1.39–8.88). Conclusion PPIs are adequate in terms of indication and form of use, however, prolonged use associated with old age, being overweight and use of anti-inflammatories and antidepressants is frequent.

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Section: Introductionmentioning

confidence: 99%

Proton pump inhibitor and community pharmacies: Usage profile and factors associated with long-term use

et al. 2021

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“…The common thread among these phenomena is confusion stemming not so much from the public’s inherent ignorance but from the lack of clarity—deliberate or indeliberate—provided by the product’s labeling and marketing. The application of direct-to-consumer advertising may overwhelm the layperson’s already tenuous ability to appreciate these sources of confusion …”

Section: Introductionmentioning

confidence: 99%

“…The application of direct-to-consumer advertising may overwhelm the layperson's already tenuous ability to appreciate these sources of confusion. 4,5 Clinicians who treat sinonasal disease may underestimate the inventory of purported remedies with which their patients are confronted. Conversely, despite a vast inventory, the actual limited scope of distinct OTC medication options available for sinonasal relief may be unappreciated by the consumer.…”

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confidence: 99%

Assessment of Pharmacologic Ingredients in Common Over-the-Counter Sinonasal Medications

McCoul

2020

JAMA Otolaryngol Head Neck Surg

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IMPORTANCE Sinonasal remedies are the most frequently purchased category of over-the-counter (OTC) drugs in the United States. A variety of options for relief are available under proprietary names, although the actual number of available options may not be readily appreciated by the consumer or the clinician.OBJECTIVE To determine the prevalence of specific ingredients in OTC sinonasal products. DESIGN, SETTING, AND PARTICIPANTSThis cross-sectional study took physical inventory of brand-name and generic OTC drugs marketed as sinus, cold, allergy, or nasal remedies. Retail pharmacies in New Orleans, Louisiana, commercial websites, and the Drugs, Herbs and Supplements section of MedlinePlus and drugs.com were searched. Data were collected and analyzed from July 1 to 31, 2018. MAIN OUTCOMES AND MEASURES Frequency of active ingredients in OTC formulations.RESULTS Five pharmacies were visited to identify 18 brands, for which the commercial websites were then searched. The 14 most common brands represented 211 unique products. Only 8 unique nonanalgesic ingredients were identified among these products, with many products sold under the same brand name and with the same active ingredient. Phenylephrine hydrochloride, dextromethorphan hydrobromide, pseudoephedrine hydrochloride, guaifenesin, chlorpheniramine maleate, brompheniramine maleate, diphenhydramine hydrochloride, and doxylamine succinate were the common active ingredients, with all available OTC sinonasal remedies consisting of 1 or more of these ingredients. The frequency of occurrence of each ingredient ranged from 10 to 261 different products. Combinations of 2, 3, or 4 active ingredients occurred frequently in OTC sinonasal products.CONCLUSIONS AND RELEVANCE These findings suggest that proliferation of brand extension products under a common name is pervasive. Clinicians should be aware of the large array of redundant OTC formulations and lack of specificity when discussing brand-name sinonasal remedies with their patients.

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“…Broadly, the options can be categorized as drugs available only by prescription and those available as over‐the‐counter (OTC) formulations. The remedy ultimately chosen by the patient or consumer depends on several factors, including access to a health care provider who can provide a prescription, notions about the relative effectiveness of prescription versus OTC agents, awareness of the nature and severity of one’s symptoms or illness, and financial considerations 2 , 3 . In contrast to prescription drugs that are, by definition, utilized under the direction of a health care practitioner, the use of OTC drugs may be minimized by clinicians and taken for granted by the patients who use them.…”

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confidence: 99%

Contemporary Role and Regulation of Over‐the‐Counter Sinonasal Medications

McCoul

2020

Otolaryngol.--head neck surg.

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Objective Numerous pharmaceutical options are available over-the-counter (OTC) for the relief of sinonasal symptoms. Patients typically utilize these drugs in an unsupervised manner, without appreciation of their relative efficacy or potential for adverse effects. This review covers the scope and regulation of the OTC drug market, the pros and cons of OTC availability, and specific concerns that surround the most common classes of OTC sinonasal drugs. Suggestions are provided for the improvement of patient care and public health. Data Sources MEDLINE publications and market reports. Review Methods Literature review. Conclusions Some of the most commonly used OTC sinonasal remedies, including decongestants and first-generation antihistamines, are less effective than alternative drugs and pose potential safety concerns. Implications for Practice Clinicians should advocate to their patients for the appropriate use of alternative agents, such as intranasal corticosteroids and newer-generation antihistamines, and discourage the unsupervised use of oral and topical decongestants. Furthermore, health care practitioners should encourage dialogue with their patients about the use of OTC sinonasal remedies, with the goals of optimizing individual health and health care delivery.

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Direct‐To‐Consumer Advertising of Over‐the‐Counter Sinonasal Remedies: A History of Mixed Messages

Cited by 7 publications

References 13 publications

Proton pump inhibitor and community pharmacies: Usage profile and factors associated with long-term use

Proton pump inhibitor and community pharmacies: Usage profile and factors associated with long-term use

Assessment of Pharmacologic Ingredients in Common Over-the-Counter Sinonasal Medications

Contemporary Role and Regulation of Over‐the‐Counter Sinonasal Medications

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