Proton pump inhibitor and community pharmacies: Usage profile and factors associated with long-term use

Araújo, Lorena Maria Lima de; Lopes, Maria Vivyanne de Moura; Arruda, Rafael Silva de; Martins, Rand Randall; Oliveira, António Gouveia

doi:10.1371/journal.pone.0252785

Cited by 4 publications

(2 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Pre-existing chronic respiratory conditions may increase the risk of a COVID-19 pneumonia becoming severe and life-threatening [ 13 ]. In addition, malnutrition is more prevalent in adults with comorbidities, being present in 24.6%, 23.3% and 12.9% of cognitively impaired, hypertensive, and diabetic older adults, respectively [ 14 ].…”

Section: Resultsmentioning

confidence: 99%

Nursing homes during the COVID-19 pandemic: a scoping review of challenges and responses

2021

View full text Add to dashboard Cite

Introduction COVID-19 has caused unprecedented challenges in nursing homes. In this scoping review, we aimed to describe factors that contributed to the spread and mortality of COVID-19 in nursing homes and provide an overview of responses that were implemented to try to overcome such challenges. Methods The MeSH terms “Nursing homes” and “COVID-19” were searched in MEDLINE Ovid, and English language articles were retrieved that were published between 1 March 2020 and 31 January 2021. Article titles and abstracts were screened by two reviewers, and the results of included articles were grouped by themes. Results The search retrieved 348 articles, of which 76 were included in the thematic review. 8 articles related to COVID-19 disease characteristics (e.g. asymptomatic transmission), 24 to resident-related factors (e.g. comorbidities, nutrition, cognition), 13 to facility characteristics (e.g. physical space, occupancy, for-profit status), 21 to staffing (e.g. staffing levels, staff-to-resident ratio, staff multi-employment), and 10 to external factors (e.g. availability of personal protective equipment, prevailing health and social care policies). In terms of responses, identified themes included widespread testing, isolation and cohorting of residents, staff protection and support, promotion of residents’ well-being, and technological innovations. Conclusion COVID-19 exerted severe challenges on the nursing home population and its staff. Both internal and external factors predisposed nursing homes to an increased propensity of spread. Numerous strategies were employed to attempt to mitigate the negative impacts. Substantial learning occurred that may not only aid future pandemic preparedness but improve quality of care for nursing home residents at all times.

show abstract

Section: Resultsmentioning

confidence: 99%

Nursing homes during the COVID-19 pandemic: a scoping review of challenges and responses

2021

View full text Add to dashboard Cite

show abstract

“…Proton pump inhibitors (PPIs) are one of the most successful therapeutic agents to treat gastric acid-related disease 1 . They are also one of the most frequently prescribed drugs for gastric ulcers and can be purchased over-the-counter without a prescription in many countries 2 . However, studies have shown that 40–60% of PPI use is inappropriate, mainly misused or overused 3 .…”

Section: Introductionmentioning

confidence: 99%

Association of suicidal ideation and depression with the use of proton pump inhibitors in adults: a cross-sectional study

Fong

Chan²,

Lei³

et al. 2022

Sci Rep

View full text Add to dashboard Cite

Proton pump inhibitors (PPIs) were found to be associated with depression. This study aimed to find the cross-sectional association between recent PPI use and suicidal ideation. Item 9 of Patient Health Questionnaire-9 (PHQ-9) of the US National Health and Nutrition Examination Survey (NHANES) between 2005 and 2018 was used to categorize whether or not the participants had suicidal ideation. The secondary outcome of this study was depression and the scores of the PHQ-9 were used as the depression diagnostic instrument. The study population included 16,881 participants who were over 20 years old. The bivariate Rao-Scott χ2 test showed a significant association between PPI use and suicidal ideation (P < 0.001) and a stronger association was observed between PPIs and depression (P < 0.001). Multiple logistic regression analysis of the education, gender, race and age-adjusted model revealed that the PPI users had a 2.34 (95% CI 1.66–3.31) greater risk of having suicidal ideation than the non-PPI users. Middle-aged participants (40–49 years) showed the greatest number of differences in suicidal ideation between PPI and non-PPI users (P < 0.001). Future research should continue to consider the psychiatric effects of taking PPIs.

show abstract

Magnitude and Determinants of Long-term Use of Proton Pump Inhibitors Among Portuguese Older Adults in Primary Health Care

Rodrigues,

Herdeiro,

Mateos-Campos

et al. 2024

Clinical Therapeutics

View full text Add to dashboard Cite

Proton pump inhibitor and community pharmacies: Usage profile and factors associated with long-term use

Cited by 4 publications

References 14 publications

Nursing homes during the COVID-19 pandemic: a scoping review of challenges and responses

Nursing homes during the COVID-19 pandemic: a scoping review of challenges and responses

Association of suicidal ideation and depression with the use of proton pump inhibitors in adults: a cross-sectional study

Magnitude and Determinants of Long-term Use of Proton Pump Inhibitors Among Portuguese Older Adults in Primary Health Care

Contact Info

Product

Resources

About