1997
DOI: 10.1016/s0925-4005(97)80199-2
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Direct immunosensing with an integrated-optical output grating coupler

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Cited by 40 publications
(35 citation statements)
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“…The way to correct the drift of effective refractive indexes in the system of output grating coupler has been presented in Ref. 45. In some cases as, e.g., in gas chemical sensors, the drift affected by the change of the refractive index of wave− guide film can be controlled by the application of a refer− ence path.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The way to correct the drift of effective refractive indexes in the system of output grating coupler has been presented in Ref. 45. In some cases as, e.g., in gas chemical sensors, the drift affected by the change of the refractive index of wave− guide film can be controlled by the application of a refer− ence path.…”
Section: Discussionmentioning
confidence: 99%
“…The resolution is limited by temperature fluctuations. In practice, it is possible to ensure temperature stabilization at the level of 0.1-0.2 K [20,44,45], which means that the detection limit involving the measurement of refractive index changes is limited to the level of (Dn c ) miñ 10 -5 RIU. Hence, we can observe that the sensitivities of sensor structures presented in the work are sufficient for the measurements of refractive indexes of water solutions and can be applied in biochemical measurements.…”
Section: Discussionmentioning
confidence: 99%
“…Photonic structures serving as an output systems may also be applied in sensor systems [20]. Sensor structures with grating couplers may be used in gas sensors for detecting changes of the refractive index in the sur− rounding medium, basing on measure of changes of the der− ivation angle Q of the electromagnetic wave from the optic waveguide [21].…”
Section: Input-output Systems Based On Hybrid Structuresmentioning
confidence: 99%
“…Applications of grating couplers in biological and chemical sensing are well known Lukosz et al, 1991;Nellen and Lukosz, 1993;Brandenberg and Gombert, 1993;Clerc and Lukosz, 1997. High sensitivity and real time data analysis Brecht and Gauglitz, 1998 provide the great interest in this type of sensors nowadays.…”
Section: Introductionmentioning
confidence: 99%