Direct Comparative Effects of Isoflurane and Desflurane in Isolated Guinea Pig Hearts

Influence of genetic background on ex vivo and in vivo cardiac function in several commonly used inbred mouse strains

“…Conversely, during in vivo measurement of cardiac function, mice were constantly anesthetized with isoflurane. Isoflurane has been shown to have strain-dependent cardiodepressive effects in vivo (8,9,28,30,46). Additionally, isoflurane anesthesia has been shown to be cardioprotective from ischemic injury through mechanisms that are not fully understood but are thought to mimic ischemic preconditioning (25).…”

Efeitos eletrocardiográficos do butorfanol em cães anestesiados pelo desfluorano

“…O valor encontrado, mesmo estando dentro da faixa de normalidade para a espécie pode ser conseqüência de mecanismo compensatório, uma vez que a variável comporta-se de modo inversamente proporcional à freqüência cardíaca (TILLEY, 1992). Desta forma a condução elétrica poderia se prolongar proporcionando maior tempo de diástole ventricular e conseqüentemente maior tempo para o enchimento das cavidades ventriculares como resposta à redução da FC (ROYSTER et al, 1988;BOBAN et al, 1992;SANTOS et al, 2001).…”

Effects of volatile anaesthetic agents on enhanced airway tone in sensitized guinea pigs

“…The guinea pigs were then randomly assigned to receive no volatile anaesthetic (n=5) or halothane (n=10), sevo¯urane (n=7), iso¯urane (n=10) or des¯urane (n=7) at a concentration of 1 MAC. MAC values for the guinea pigs were established as 1% for halothane, 24 1.2% for iso¯urane, 24 6.4% for des¯urane 25 and 2% for sevo¯urane. 26 Changes in lung mechanics during gas administration were followed by measuring ZL at 1 min intervals for 10 min.…”