Diphtheria and tetanus seroepidemiology among children in Ukraine, 2017

Khetsuriani, Nino; Zaika, Oleksandr; Slobodianyk, Liudmyla; Scobie, Heather M.; Cooley, Gretchen; Dimitrova, Silvia D.; Stewart, Brock; Geleishvili, Marika; Allahverdiyeva, Vusala; O’Connor, Patrick; Huseynov, Shahin

doi:10.1016/j.vaccine.2022.02.006

Cited by 7 publications

(11 citation statements)

References 27 publications

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“…Vaccination rates increased dramatically after that study, due to a large measles outbreak that resulted in a number of deaths 120 . Another study indicated that 34%–54% of Ukrainian children born in 2011–2015 had received appropriate diphtheria‐tetanus vaccinations, but this meant that 46–66% were not fully vaccinated 62 . It is notable that WHO data have suggested higher vaccination rates in recent years (Figure 4).…”

Section: Resultsmentioning

confidence: 99%

“…After duplicates were removed, the titles and abstracts of 1,628 reports were reviewed by one of the authors (JFL), and 131 met the eligibility criteria (Figure 1). The current review was primarily based on 107 full papers, 2‐108 but, due to the scarcity of data, we also chose to cite five relevant abstracts 109‐113 for a more complete picture of child health in Ukraine. Our literature search was limited to papers published in English.…”

Section: Methodsmentioning

confidence: 99%

“…120 Another study indicated that 34%-54% of Ukrainian children born in 2011-2015 had received appropriate diphtheria-tetanus vaccinations, but this meant that 46-66% were not fully vaccinated. 62 It is notable that WHO data have suggested higher vaccination rates in recent years (Figure 4). 121 Polio cases are extremely rare in Ukraine, but have occurred in the last decade.…”

Section: Vaccinations and Vaccinepreventable Diseasesmentioning

confidence: 99%

“…62 Protection against tetanus was deemed sufficient in three of the above regions, but not in the Zakarpattya region, where the seroprevalence for antibodies was 62%. 62 Perinatal syphilis occurs in Ukraine, 56 but is very rare. It affected 0.07% of all pregnant women in Ukraine in 2016, with a more than 92% screening coverage and 100% treatment coverage of known cases.…”

Section: Other Infectionsmentioning

confidence: 99%

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Systematic review of health and disease in Ukrainian children highlights poor child health and challenges for those treating refugees

Ludvigsson

Лобода

2022

Acta Paediatrica

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Aim Millions of Ukrainian children have been internally displaced or fled to other countries because of the Russian war. This systematic review focused on their health needs and future challenges for clinicians. Methods A systematic literature search of the Medline, Embase and MedRxiv databases from 1 January 2010 to 31 March 2022 identified 1628 papers on the health of Ukrainian children and 112 were relevant to this review. Results In 2019, under‐5 mortality was 8 per 1000 live births in Ukraine. Underweight and adverse childhood experiences, including child abuse, were frequent compared to other European countries, while childhood obesity seemed less common. Alcohol consumption was common in women of reproductive age, including during pregnancy, risking foetal alcohol syndrome. Neonatal screening programmes provided low coverage. Vaccine hesitancy was common and vaccination rates were low. Other concerns were measles, HIV, antibiotic resistance and multi‐resistant tuberculosis. Many children are expected to suffer from psychological and physical trauma due to the war. Other healthcare challenges include low COVID‐19 vaccination rates and a preference for secondary and tertiary care, rather than primary care. Many people cannot afford medication. Conclusion Ukrainian children often have poor health and host countries need to be aware of their needs.

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Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Vaccinations and Vaccinepreventable Diseasesmentioning

confidence: 99%

Section: Other Infectionsmentioning

confidence: 99%

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Systematic review of health and disease in Ukrainian children highlights poor child health and challenges for those treating refugees

Ludvigsson

Лобода

2022

Acta Paediatrica

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“…Daten aus der Ukraine aus dem Jahr 2021 zeigen eine Impfquote von 87 % für MMR sowie 80 % für die dreimalige Impfung gegen Diphtherie, Tetanus und Pertussis (DTP3) [11] Auch bei der DTP3-Impfung brachen die Impfquoten im Jahr 2016 auf bis zu 20 % ein (siehe ▶ abb. 2), bei gleichzeitigem Anstieg der Pertussis-Inzidenz [10,16]. Die Polio-Impfquote ging auf unter 50 % zurück.…”

Section: Impfpräventable Erkrankungenunclassified

Gesundheitliche Lage in der Ukraine vor Kriegsbeginn und ihre Relevanz für die Versorgung ukrainischer Geflüchteter in Deutschland: Literaturdurchsicht, Risikoanalyse und Prioritätensetzung

Butenop¹,

Brake

Mauder

et al. 2022

Gesundheitswesen

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Zusammenfassung Hintergrund Die gesundheitlichen Bedarfe Geflüchteter ergeben sich nicht nur aus Expositionen während Krieg und Flucht. Auch Determinanten aus dem Lebenslauf und etabliertes Gesundheitsverhalten spielen eine Rolle. Wir untersuchten daher die gesundheitliche Lage in der Ukraine vor der russischen Invasion 2022 und ihre Relevanz für die Versorgung ukrainischer Geflüchteter in Deutschland aus Sicht des Öffentlichen Gesundheitsdienstes (ÖGD). Methode Rapid Review in der Medline-Datenbank sowie Suche in einschlägigen ukrainischen und internationalen Gesundheitsdatenbanken. Narrative Synthese der Ergebnisse, gefolgt von einer Priorisierung der Gesundheitsprobleme und Maßnahmen durch zwei Mediziner mithilfe des Risikomatrix-Ansatzes. Ergebnisse Niedrige Impfquoten bestehen bei Covid-19 und führen zu Ausbrüchen in Unterkünften. Bei Masern und anderen Grundimmunisierungen bestehen Impflücken überwiegend bei älteren Kindern; 2–5-Jährige haben die zweite Masernimpfung noch nicht erhalten. HIV- und Tuberkulose-Therapien können durch die Flucht unterbrochen sein. Kommen zunehmend ältere Geflüchtete, so stehen aufgrund der Flucht unzureichend behandelte Herz-Kreislauferkrankungen und vorbestehende psychische Traumatisierung sowie ggf. akut therapiebedürftige Krebserkrankungen im Vordergrund. Bei ukrainischen Geflüchteten kann ein Misstrauen gegenüber mit dem Staat assoziierten Gesundheitsmaßnahmen bestehen, wie die Impflücken zeigen. Schlussfolgerung Der Zugang Geflüchteter zu kurativer und präventiver Gesundheitsversorgung sollte ohne bürokratische Hürden und Einschränkungen gewährleistet werden. Durch die Analyse von Gesundheitsstatistiken der Ukraine sowie wissenschaftlicher Publikationen können Angebote des ÖGD besser angepasst und ein Fehleinsatz von Ressourcen vermieden werden.

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Phylogenomic diversity within Corynebacterium diphtheriae, a reemerging threat to global public health

Burkovski,

Sangal

2024

Phylogenomics

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Diphtheria and tetanus seroepidemiology among children in Ukraine, 2017

Cited by 7 publications

References 27 publications

Systematic review of health and disease in Ukrainian children highlights poor child health and challenges for those treating refugees

Systematic review of health and disease in Ukrainian children highlights poor child health and challenges for those treating refugees

Gesundheitliche Lage in der Ukraine vor Kriegsbeginn und ihre Relevanz für die Versorgung ukrainischer Geflüchteter in Deutschland: Literaturdurchsicht, Risikoanalyse und Prioritätensetzung

Phylogenomic diversity within Corynebacterium diphtheriae, a reemerging threat to global public health

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