Diode Laser Treatment of Retinopathy of Prematurity

Abstract

DLPC is a safe and effective treatment for ROP. Neonates of lower gestational age and birth weight require earlier and more aggressive laser treatment and may have a higher refractive error.

Treatment success of laser therapy for retinopathy of prematurity in referred and non-referred patients

“…Here the anatomic success rate for referred patients was 93%; however, the anatomic success rate for non-referred patients was 100%. The overall anatomic success rate in our clinic was 96.1%, and this rate is consistent with previous studies, which have reported success rates above 90% (10)(11)(12)(13)(14)(15) . Thus, we found a significantly better success rate in the non-referred group.…”

“…Low BW and small GA are known to be risk factors for the development of ROP (18) . Many previous studies included treatment groups mainly consisting of preterm patients weighing <1000 g and aged <28 weeks (10,(19)(20)(21) . In our study, consistent with previous reports, the average BW and GA in patients who received treatment were 900 g and 27 weeks, respectively; although these values were higher among referred patients, they were not statistically significant.…”

Refractive errors after the use of bevacizumab for the treatment of retinopathy of prematurity: 2-year outcomes

“…9,10,17 Our study and other case series found a lower SE in patients treated with IVB than in patients treated with cryotherapy (range, À 6.5 to À 3.51 D) or with laser peripheral ablative therapy (range, À 4.71 to À 1.50 D). [3][4][5][6][7] Our prevalences of myopia and high myopia are also similar to those of preschool-age patients in a recent case series who were treated with IVB only (55.6% and 11.1 to 17.0%) ( Table 3). 9,10,17 In the current study, the prevalences of myopia and high myopia increased significantly with the severity of ROP but were not associated with AXL changes.…”

“…The reported rates range from 55.2 to 80.4% and 23.9 to 31.5%, respectively (Table 3). 3,4,6 The reported rates of myopia and high myopia were even higher in patients treated with cryotherapy, ranging from 82.9 to 92.0% and 32.0 to 52.5%, respectively (Table 3). [5][6][7] In the current study, the percentages of patients with myopia and high myopia among IVB-treated patients were 47.5 and 10.0%, respectively, which are less than the previously reported percentages for patients treated with laser treatment or cryotherapy.…”

“…2 However, many investigators have reported high prevalences of myopia and high myopia in preschool-and school-age children who received ablative therapy. [3][4][5][6][7] For these patients, it has been reported that laser treatment for severe ROP results in less myopia than cryotherapy. 6 In the last several years, anti-vascular endothelial growth factor (VEGF) agents have emerged as a new treatment for ROP, and promising experiences have been reported.…”