Dinuclear rectangular-shaped assemblies of bis-benzimidazolydine salt coordinated to Ag(I) and Cu(I) N-heterocyclic carbene complexes and their biological applications

Dileepan, A.G. Bharathi; Kumar, Anuj; Mathumidha, R.; Rajaram, R. Κ.; Rajam, Shameela

doi:10.1007/s11696-018-0538-z

Cited by 7 publications

(4 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In contrast to this, ligands and copper−NHC complex 25 exhibited less than 10 % of PI penetration rate. The results indicated that Amphoterin B and silver−NHC complex 24 were found to be more effective against Candida species than that of copper−NHC complexes [44] …”

Section: Medicinal Applicationsmentioning

confidence: 99%

“…The ligand precursor was then reacted with Ag 2 O in water for 48 hours to obtain Ag I −NHC complex 24 , which was converted to Cu І −NHC complex 25 by reacting the complex 24 with Cu in acetonitrile at 55 °C (Scheme 7). [44] …”

Section: Synthetic Strategiesmentioning

confidence: 99%

“…The results indicated that Amphoterin B and silverÀ NHC complex 24 were found to be more effective against Candida species than that of copperÀ NHC complexes. [44]…”

Section: Copperà Nhc Complexes As Antimicrobial Agentsmentioning

confidence: 99%

See 2 more Smart Citations

Coinage Metal N‐Heterocyclic Carbene Complexes: Recent Synthetic Strategies and Medicinal Applications

Nayak

Gaonkar

2021

ChemMedChem

View full text Add to dashboard Cite

New weapons are constantly needed in the fight against cancer. The discovery of cisplatin as an anticancer drug prompted the search for new metal complexes. The successful history of cisplatin motivated chemists to develop a plethora of metal‐based molecules. Among them, metal‐N‐heterocyclic carbene (NHC) complexes have gained significant attention because of their suitable qualities for efficient drug design. The enhanced applications of coinage metal‐NHC complexes have encouraged a gradually increasing number of studies in the fields of medicinal chemistry that benefit from the fascinating chemical properties of these complexes. This review aims to present recent developments in synthetic strategies and medicinal applications of copper, silver and gold complexes supported by NHC ligands.

show abstract

Section: Medicinal Applicationsmentioning

confidence: 99%

Section: Synthetic Strategiesmentioning

confidence: 99%

See 1 more Smart Citation

Coinage Metal N‐Heterocyclic Carbene Complexes: Recent Synthetic Strategies and Medicinal Applications

Nayak

Gaonkar

2021

ChemMedChem

View full text Add to dashboard Cite

show abstract

“…Many of those new chemicals have silver in their structure, which is interesting since silver has been used since the times of ancient Greece as an antimicrobial. Examples of the Ag-containing compounds synthesized include those containing camphorimines, tetraazoles, albendazoles or phenantrolines as ligands (Table 5) [145][146][147][148]. Complexes with other metal centers like copper, cobalt, nickel or iron; or even with metals not usually used as bioagents, such as tin, chromium, cadmium or lead [149][150][151][152][153][154][155][156][157], have also been synthesized and shown to display moderate anti C. albicans activity ( Table 5).…”

Section: New Compounds Obtained By Chemical Synthesismentioning

confidence: 99%

An Overview on Conventional and Non-Conventional Therapeutic Approaches for the Treatment of Candidiasis and Underlying Resistance Mechanisms in Clinical Strains

Salazar

Simões

Pedro

et al. 2020

JoF

View full text Add to dashboard Cite

Fungal infections and, in particular, those caused by species of the Candida genus, are growing at an alarming rate and have high associated rates of mortality and morbidity. These infections, generally referred as candidiasis, range from common superficial rushes caused by an overgrowth of the yeasts in mucosal surfaces to life-threatening disseminated mycoses. The success of currently used antifungal drugs to treat candidiasis is being endangered by the continuous emergence of resistant strains, specially among non-albicans Candida species. In this review article, the mechanisms of action of currently used antifungals, with emphasis on the mechanisms of resistance reported in clinical isolates, are reviewed. Novel approaches being taken to successfully inhibit growth of pathogenic Candida species, in particular those based on the exploration of natural or synthetic chemicals or on the activity of live probiotics, are also reviewed. It is expected that these novel approaches, either used alone or in combination with traditional antifungals, may contribute to foster the identification of novel anti-Candida therapies.

show abstract

Allyl Functionalized Benzimidazolium-Derived Ag(I)-N-Heterocyclic Carbene Complexes: Anti-Biofilm and Antimicrobial Properties

2022

View full text Add to dashboard Cite

Dinuclear rectangular-shaped assemblies of bis-benzimidazolydine salt coordinated to Ag(I) and Cu(I) N-heterocyclic carbene complexes and their biological applications

Cited by 7 publications

References 49 publications

Coinage Metal N‐Heterocyclic Carbene Complexes: Recent Synthetic Strategies and Medicinal Applications

Coinage Metal N‐Heterocyclic Carbene Complexes: Recent Synthetic Strategies and Medicinal Applications

An Overview on Conventional and Non-Conventional Therapeutic Approaches for the Treatment of Candidiasis and Underlying Resistance Mechanisms in Clinical Strains

Allyl Functionalized Benzimidazolium-Derived Ag(I)-N-Heterocyclic Carbene Complexes: Anti-Biofilm and Antimicrobial Properties

Contact Info

Product

Resources

About