Dímero-D Como Importante Marcador Para Estratificar a Gravidade Da Infecção Pelo Novo Coronavírus: Revisão Sistemática Da Literatura

Bruno, Luca; Soares, J.A.H.; Lelis, E. S. D. S.; Martins, Rosa Maria Grangeiro; Pinto, T.; Silva, I.P.; Alencar, K.C.; Araújo, M.E.S.O.; Nunes, Christiane Girard Ferreira; Gonçalves, Paulo

doi:10.1016/j.htct.2020.10.895

Cited by 4 publications

(2 citation statements)

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“…In recent years, some biomarkers of inflammation and systemic coagulation have become available in the main analyzers of laboratory tests and can help in terms of tracking and detecting the severity of the disease [ 25 ]. It was found that there were high D-dimer levels in critically ill patients, just as the Chinese retrospective study showed that D-dimer levels showed higher values at the time of hospital admission in those patients who evolved to a severe or critical illness and required intensive treatment [ 26 ].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of oxidative stress level: reactive oxygen species, reduced glutathione, and D-dimer in patients hospitalized due to COVID-19

Roessler,

de Oliveira,

de Oliveira Portella

et al. 2023

Redox Report

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Elevated D-dimer levels at hospital admission may also indicate a higher likelihood of progressing to a severe or critical state. This study aimed to assess reactive oxygen species (ROS), non-enzymatic antioxidant reduced glutathione (GSH), and D-dimer levels in COVID-19 patients upon admission, examining their association with mortality outcomes. Data was collected from the medical records of 170 patients hospitalized in a referral hospital unit between March 2020 and December 2021. Patients were divided into two groups: the ward bed group ( n = 87), comprising 51% with moderate clinical conditions, and the intensive care unit (ICU) group ( n = 83), comprising 49% with severe conditions. The mean age was 59.4 years, with a male predominance of 52.4%. The overall death rate was 43%, with 30.6% in the moderate group and 69.4% in the severe group. The average time from symptom onset to hospitalization was 6.42 days. Results showed that non-survivors had high D-dimer and ROS counts, longer ICU stays, and worse saturation levels at admission. In conclusion, elevated ROS and D-dimer levels may contribute to worse outcomes in critically ill patients, potentially serving as specific and sensitive predictors of poor outcomes upon admission.

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Section: Discussionmentioning

confidence: 99%

Evaluation of oxidative stress level: reactive oxygen species, reduced glutathione, and D-dimer in patients hospitalized due to COVID-19

Roessler,

de Oliveira,

de Oliveira Portella

et al. 2023

Redox Report

View full text Add to dashboard Cite

show abstract

“…The reference value of DD in blood is up to 0.5 mcg/ml. In COVID-19, values above 1 mcg/ml are associated with mortality and hypercoagulability 66 , 67 , which can be predictive of the severity of cases and longer hospitalization periods. The material used is plasma in citrate and the method is immunoturbidimetric with reference values lower than 0.5 mcg/ml.…”

Section: Methodsmentioning

confidence: 99%

Relation between Orotracheal Intubation, Inflammatory Markers, Breathing and Voice in Post-COVID-19

2023

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INFECCIÓN POR SARS-CoV-2/ COVID-19 Y SÍNDROME TORÁCICO AGUDO EN NIÑOS CON DREPANOCITOSIS: REPORTE DE CASO

Medina-Garcia,

López-Verón,

Ramírez-Melo

et al. 2023

Rev. Fac. Cienc.

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A medida que el SARS-CoV-2/ COVID-19 continúa propagándose en todo el mundo, se han aumentado los informes de pacientes pediátricos con infección de curso complicado y antecedente de enfermedad crónica. En este artículo se da a conocer el caso de una paciente de 11 años con antecedente de anemia de células falciformes variedad homocigota SS e infección grave por SARS-CoV-2/ COVID-19 que desarrolla síndrome torácico agudo. Se recomienda en esta patología, reconocer a tiempo la infección en un intento por prevenir complicaciones relacionadas con la enfermedad de base y desenlace fatal.

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Dímero-D Como Importante Marcador Para Estratificar a Gravidade Da Infecção Pelo Novo Coronavírus: Revisão Sistemática Da Literatura

Cited by 4 publications

References 0 publications

Evaluation of oxidative stress level: reactive oxygen species, reduced glutathione, and D-dimer in patients hospitalized due to COVID-19

Evaluation of oxidative stress level: reactive oxygen species, reduced glutathione, and D-dimer in patients hospitalized due to COVID-19

Relation between Orotracheal Intubation, Inflammatory Markers, Breathing and Voice in Post-COVID-19

INFECCIÓN POR SARS-CoV-2/ COVID-19 Y SÍNDROME TORÁCICO AGUDO EN NIÑOS CON DREPANOCITOSIS: REPORTE DE CASO

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