Dimensionen der Hamilton-Depressionsskala (HAMD)

Maier, Wolfgang; Philipp, Michael; Gerken, A.

doi:10.1007/bf00386061

Cited by 52 publications

(22 citation statements)

References 18 publications

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“…Low mood, a core symptom of depression, was assessed by a HAM-D subscale consisting of items 1 (Depressed Mood), 2 (Guilt), 3 (Suicide), 7 (Loss of Interest), and 10 (Anxiety). Somatic complaints were measured by a HAM-D subscale defined by the cluster of items 11 (Anxiety Somatic), 12 (Gastro-intestinal Symptoms), and 13 (General Symptoms) [30, 31]. …”

Section: Methodsmentioning

confidence: 99%

Effects of hyperthermic baths on depression, sleep and heart rate variability in patients with depressive disorder: a randomized clinical pilot trial

Naumann

Grebe

Kaifel

et al. 2017

BMC Complement Altern Med

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BackgroundDespite advances in the treatment of depression, one-third of depressed patients fail to respond to conventional antidepressant medication. There is a need for more effective treatments with fewer side effects. The primary aim of this study was to determine whether hyperthermic baths reduce depressive symptoms in adults with depressive disorder.MethodsRandomized, two-arm placebo-controlled, 8-week pilot trial. Medically stable outpatients with confirmed depressive disorder (ICD-10: F32/F33) who were moderately depressed as determined by the 17-item Hamilton Scale for Depression (HAM-D) score ≥18 were randomly assigned to 2 hyperthermic baths (40 °C) per week for 4 weeks or a sham intervention with green light and follow-up after 4 weeks. Main outcome measure was the change in HAM-Dtotal score from baseline (T0) to the 2-week time point (T1).ResultsA total of 36 patients were randomized (hyperthermic baths, n = 17; sham condition, n = 19). The intention-to-treat analysis showed a significant (P = .037) difference in the change in HAM-Dtotal score with 3.14 points after 4 interventions (T1) in favour of the hyperthermic bath group compared to the placebo group.ConclusionsThis pilot study suggests that hyperthermic baths do have generalized efficacy in depressed patients.Trial registration DRKS00004803at drks-neu.uniklinik-freiburg.de, German Clinical Trials Register (registration date 2016-02-02), retrospectively registered.Electronic supplementary materialThe online version of this article (doi:10.1186/s12906-017-1676-5) contains supplementary material, which is available to authorized users.

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Section: Methodsmentioning

confidence: 99%

Effects of hyperthermic baths on depression, sleep and heart rate variability in patients with depressive disorder: a randomized clinical pilot trial

Naumann

Grebe

Kaifel

et al. 2017

BMC Complement Altern Med

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“…As already laid out in our earlier paper (Volz et al 2000), the HAMA-SOM was selected as the primary outcome criterion, since (i) the HAMA and HAMA-SOM have proven to be sensitive measures for change (Maier et al 1985;Van Riezen and Segal 1998) and (ii) these scales are reliable and valid (Maier et al 1988;AMDP and CIPS, 1996). Neither sensitivity nor validity has been proven for scales more specifically constructed to detect somatic complaints (such as the Bradford Somatic Inventory, BSI; Mumford et al 1991).…”

Section: Methodsmentioning

confidence: 99%

St John's wort extract (LI 160) in somatoform disorders: results of a placebo-controlled trial

Volz¹,

Murck

Kasper

et al. 2002

Psychopharmacology

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“…The use of the HAMD-17 as a measure of outcome might be another limitation [30]. Although the HAMD-17 is the most commonly used rating scale for depression severity [30], the ability of the HAMD-17 in judging depression severity is still doubtful [31]. …”

Section: Discussionmentioning

confidence: 99%

Are Treatment Preferences Relevant in Response to Serotonergic Antidepressants and Cognitive-Behavioral Therapy in Depressed Primary Care Patients? Results from a Randomized Controlled Trial Including a Patients’ Choice Arm

Mergl

Henkel²,

Allgaier³

et al. 2010

Psychother Psychosom

112

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Background: Little is known about the influence of depressed patients’ preferences and expectations about treatments upon treatment outcome. We investigated whether better clinical outcome in depressed primary care patients is associated with receiving their preferred treatment. Methods: Within a randomized placebo-controlled single-centre 10-week trial with 5 arms (sertraline; placebo; cognitive-behavioral group therapy, CBT-G; moderated self-help group control; treatment with sertraline or CBT-G according to patients’ choice), outcomes for 145 primary care patients with mild-to-moderate depressive disorders according to DSM-IV criteria were investigated. Preference for medication versus psychotherapy was assessed at screening using a single item. Post-baseline difference scores for the Hamilton Depression Rating Scale (HAMD-17) were used to assess treatment outcome (mixed-model repeated-measures regression analysis). Results: Depressed patients receiving their preferred treatment (n = 63), whether sertraline or CBT-G, responded significantly better than those who did not receive their preferred therapy (n = 54; p = 0.001). The difference in outcome between both groups was 8.0 points on the HAMD-17 for psychotherapy and 2.9 points on the HAMD-17 for treatment with antidepressants. Results were not explained by differences in depression severity or dropout rates. Conclusions: Patients’ relative preference for medication versus psychotherapy should be considered when offering a treatment because receiving the preferred treatment conveys an additional and clinically relevant benefit (HAMD-17: +2.9 points for drugs; +8.0 points for CBT-G) in outcome.

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Dimensionen der Hamilton-Depressionsskala (HAMD)

Cited by 52 publications

References 18 publications

Effects of hyperthermic baths on depression, sleep and heart rate variability in patients with depressive disorder: a randomized clinical pilot trial

Effects of hyperthermic baths on depression, sleep and heart rate variability in patients with depressive disorder: a randomized clinical pilot trial

St John's wort extract (LI 160) in somatoform disorders: results of a placebo-controlled trial

Are Treatment Preferences Relevant in Response to Serotonergic Antidepressants and Cognitive-Behavioral Therapy in Depressed Primary Care Patients? Results from a Randomized Controlled Trial Including a Patients’ Choice Arm

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