Diisopropylammonium hydrogen phthalate

Seye, Dame; Diop, Libasse; Diop, Cheikh; Geiger, David K.

doi:10.1107/s2414314618007046

Cited by 3 publications

(1 citation statement)

References 18 publications

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“…Its asymmetric unit is comprised of one diisopropylammonium cation and one hydrogen maleate (Figure 1). Several crystals of salts containing the diisopropylammonium cation, iPrNH 2 + are isolated and their structures reported in the literature [14,15,16,17,18].…”

Section: Crystallographic Studymentioning

confidence: 99%

Crystal Structure of Diisopropylammonium Hydrogen Maleate

Seye¹,

Toure²,

Lo³

et al. 2019

SJC

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Use of salts and co-crystals of active pharmaceutical ingredients (APIs) as a method for tuning their delivery and activity is an area of growing interest. Modifying API properties such as solubility by finding new salts that employ similar hydrogen-bonding have been successful. In an effort to further study the hydrogen-bonding patterns of the maleate ion with other diisopropylammonium we report here the synthesis and diisopropylammonium maleate. The salt was isolated from reaction between diisopropylamine and maleic acid in methanol. The results of elementary analyzes (CHN) showed the presence of the nitrogen atom of diisopropylamine, carbon atoms and hydrogen. The IR spectrum of diisopropylammonium hydrogen maleate, showed the presence of two intense bands due to the vibrations of symmetricand anti-symmetric valence of the carboxylate group and a wide absorption due to the NH 2 groups of the cation. Those which has been confirmed by crystallography. The asymmetric unit contains one diisopropylammonium cation, iPr 2 NH 2 + and one hydrogen maleate anion. In the structure, anions which present an inner O-H…O hydrogen bond are linked to cations through N-H…O hydrogen bonds leading to infinite chains. Chains are connected to their neighbours through weak C-H…O hydrogen bonds affording a layer. The study of the interactions of diisopropylammonium hydrogen menaleate, by the presence of hydrogen bonds leading to supramolecular architectures has shown the possibility of its use in Active Pharmaceutical Ingrédients (API).

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Section: Crystallographic Studymentioning

confidence: 99%

Crystal Structure of Diisopropylammonium Hydrogen Maleate

Seye¹,

Toure²,

Lo³

et al. 2019

SJC

Self Cite

View full text Add to dashboard Cite

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Investigation on the crystal growth, physicochemical, quantum chemical, and third harmonic generation properties of diisopropylammonium hydrogen phthalate single crystal

Sidden²,

Rajesh³

et al. 2022

J Mater Sci: Mater Electron

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Metrics for crystallographic diffraction- and fit-data: a review of existing ones and the need for new ones

Henn

2019

Crystallography Reviews

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Normal probability plots and corresponding histograms of the residuals for 1 and 2. Additional simulation of the histogram of data generated from two Gaussians with different variances -Fig.2: fraction of data with Miller triples being a multiple of 3 and fraction of rare events ||>3 from these fractions for 1 and 2 -Fig.3: BayCon plots (X), X = (I c , , sintl, I o / (Io)) and corresponding  2 values for 1 and 2 -Fig:4: BayCon plots (  X), X = (I c , , sintl, I o / (Io)) and corresponding  2 values for 1 and 2 -Fig5: Squared residuals in individual bins of the data sorted by significance I o / (Io); observed intensity, I o ; and resolution (sin / respectively for 1 and 2 -Fig.6: Correlation coefficients cc(  ,  cc(  ,  cc(  ,  for the data sorted in increasing order of the significance of the observed intensities for 1 and 2 -Fig 7: Diagnostic plots for the neutron diffraction data set oxa14 from Kaminski et a Description of a simulation for testing the standard deviations sqrt(1/Nref) of the correlation coefficients with the help of random numbers.

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Diisopropylammonium hydrogen phthalate

Cited by 3 publications

References 18 publications

Crystal Structure of Diisopropylammonium Hydrogen Maleate

Crystal Structure of Diisopropylammonium Hydrogen Maleate

Investigation on the crystal growth, physicochemical, quantum chemical, and third harmonic generation properties of diisopropylammonium hydrogen phthalate single crystal

Metrics for crystallographic diffraction- and fit-data: a review of existing ones and the need for new ones

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