Digital light processing porous TPMS structural HA &amp; akermanite bioceramics with optimized performance for cancellous bone repair

Hua, Shuai‐Bin; Yuan, Xianglin; Wu, Jia‐Min; Su, Jin; Cheng, Lan; Wen, Zheng; Pan, Mingzhu; Xiao, Jun; Shi, Yusheng

doi:10.1016/j.ceramint.2021.10.003

Cited by 14 publications

(3 citation statements)

References 43 publications

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“…Bioactivity is usually defined as the ability to form chemical bonds between the implanted scaffold and the host tissue, but the formation and growth ability of apatite layers after immersion in a simulated body fluid (SBF) solution has become a direct criterion for assessing the bioactivity of bone scaffolds. ,,, Degradability allows the scaffold to provide structure and stability at the initial stage of implantation and gradually degrade as new tissue forms . The evaluation of bioactivity can be performed together with degradation experiments.…”

Section: Performance Of Vp-printed Bioactive Ceramic Bone Scaffoldsmentioning

confidence: 99%

Comprehensive Review on Fabricating Bioactive Ceramic Bone Scaffold Using Vat Photopolymerization

Liu

Wang

Liu³

et al. 2023

ACS Biomater. Sci. Eng.

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In recent years, bioactive ceramic bone scaffolds have drawn remarkable attention as an alternative method for treating and repairing bone defects. Vat photopolymerization (VP) is a promising additive manufacturing (AM) technique that enables the efficient and accurate fabrication of bioactive ceramic bone scaffolds. This review systematically reviews the research progress of VP-printed bioactive ceramic bone scaffolds. First, a summary and comparison of commonly used bioactive ceramics and different VP techniques are provided. This is followed by a detailed introduction to the preparation of ceramic suspensions and optimization of printing and heat treatment processes. The mechanical strength and biological performance of the VP-printed bioactive ceramic scaffolds are then discussed. Finally, current challenges and future research directions in this field are highlighted.

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Section: Performance Of Vp-printed Bioactive Ceramic Bone Scaffoldsmentioning

confidence: 99%

Comprehensive Review on Fabricating Bioactive Ceramic Bone Scaffold Using Vat Photopolymerization

Liu

Wang

Liu³

et al. 2023

ACS Biomater. Sci. Eng.

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“…The use of heterogeneous TPMS and or even multiscale TPMS are still under research according to current knowledge. Ceramic based TPMS structures have been built on ZrO 2 [29], HA [30], SiC [31], and others, but Si 3 N 4 still has yet to be attempted.…”

Section: Materials and Processes For Implant Manufacturingmentioning

confidence: 99%

Design of Reliable Remobilisation Finger Implants with Geometry Elements of a Triple Periodic Minimal Surface Structure via Additive Manufacturing of Silicon Nitride

Koplin

Schwarzer-Fischer

Zschippang

et al. 2023

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When finger joints become immobile due to an accident during sports or a widespread disease such as rheumatoid arthritis, customised finger joint implants are to be created. In an automated process chain, implants will be produced from ceramic or metallic materials. Artificial intelligence-supported software is used to calculate three-dimensional models of the finger bones from two-dimensional X-ray images. Then, the individual implant design is derived from the finger model and 3D printed. The 3D printing process and the structures used are evaluated via model tests and the final implant design via a reliability calculation in a way to ensure that this is also possible via an AI process in the future. Using additive manufacturing with silicon nitride-based ceramics, model specimens and implants are produced via the lithography-based ceramic vat photopolymerisation process with full geometry or elements of triple periodic minimal surfaces structure. The model specimens are tested experimentally, and the loads are matched with a characteristic strength assuming a Weibull distribution of defects in the volume to generate and match failure probabilities. Calculated fracture forces of the silicon nitride-based ceramic structure was validated by comparison of simulation and tests, and the calculation can be used as a quality index for training of artificial intelligence in the future. The proposed method for individualized finger implant design and manufacturing may allow for correction of potential malpositions of the fingers in the future.

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“…However, autogenous bone grafts have limitations in terms of supply and can lead to complications at the donor site, whereas allograft bone grafts carry risks of immune rejection and infectious diseases [6]. Currently, biodegradable materials represented by biopolymers, ceramics, and metals offer new avenues for bone repair [7][8][9]. Among biomaterials, poly-L-lactic acid (PLLA) is a promising bone graft material owing to its excellent biocompatibility, biodegradability, and processability [10].…”

Section: Introductionmentioning

confidence: 99%

Zeolitic Imidazolate Frameworks Serve as an Interface Layer for Designing Bifunctional Bone Scaffolds with Antibacterial and Osteogenic Performance

Huang,

Cheng,

Yang

et al. 2023

Nanomaterials

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The integration of hydroxyapatite (HA) with broad-spectrum bactericidal nano-silver within biopolymer-based bone scaffolds not only promotes new bone growth, but also effectively prevents bacterial infections. However, there are problems such as a poor interface compatibility and easy agglomeration. In this project, zeolitic imidazolate frameworks (ZIF-8) were grown in situ on nano-HA to construct a core–shell structure, and silver was loaded into the ZIF-8 shell through ion exchange. Finally, the core–shell structure (HA@Ag) was composited with polylactic acid (PLLA) to prepare bone scaffolds. In this case, the metal zinc ions of ZIF-8 could form ionic bonds with the phosphate groups of HA by replacing calcium ions, and the imidazole ligands of ZIF-8 could form hydrogen bonds with the carboxyl groups of the PLLA, thus enhancing the interface compatibility between the biopolymers and ceramics. Additionally, the frame structure of MOFs enabled controlling the release of silver ions to achieve a long-term antibacterial performance. The test results showed that the HA@Ag nanoparticles endowed the scaffold with good antibacterial and osteogenic activity. Significantly, the HA@Ag naoaprticle exhibited a good interfacial compatibility with the PLLA matrix and could be relatively evenly dispersed within the matrix. Moreover, the HA@ZIF-8 also effectively enhanced the mechanical strength and degradation rate of the PLLA scaffold.

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Digital light processing porous TPMS structural HA & akermanite bioceramics with optimized performance for cancellous bone repair

Cited by 14 publications

References 43 publications

Comprehensive Review on Fabricating Bioactive Ceramic Bone Scaffold Using Vat Photopolymerization

Comprehensive Review on Fabricating Bioactive Ceramic Bone Scaffold Using Vat Photopolymerization

Design of Reliable Remobilisation Finger Implants with Geometry Elements of a Triple Periodic Minimal Surface Structure via Additive Manufacturing of Silicon Nitride

Zeolitic Imidazolate Frameworks Serve as an Interface Layer for Designing Bifunctional Bone Scaffolds with Antibacterial and Osteogenic Performance

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