Digestive utilization of goat and cow milk fat in malabsorption syndrome

Abstract

We studied the effects of goat and cow milk fat on the digestive utilization of this nutrient and on some of the biochemical parameters that are related to the metabolism of lipids, using rats with a resection of 50% of the distal small intestine and control animals (transected). The fat content in all the diets was 10% but the lipid quality was varied: the standard diet was based on olive oil, while the other two diets included fat obtained from lyophilized goat milk and cow milk, respectively. The digestive utilization of the fat was lower in the resected animals than in the transected ones for all three diets studied. In both resected and transected animals, the apparent digestibility coefficient (ADC) of the fat was greater with the standard diet (olive oil) than with diets whose fat content was provided by goat or cow milk. The digestive utilization of the fat was greater in the transected and resected rats receiving a diet of goat's milk (rich in medium-chain triglycerides) than those given a cow-milk-based diet, and more closely approached the values obtained for olive oil. The consumption of goat milk reduced levels of cholesterol while levels of triglycerides, HDL, GOT and GPT remained within the normal ranges, for both transected and resected animals. The advantageous effect of goat milk on the metabolism of lipids with respect to cow milk suggests that the former should be included in the diet in cases of malabsorption syndrome.

Characteristics and fatty acid composition of milk fat from Saudi Aradi goat

“…Goat milk is also recognized for its high therapeutic and nutritional value because of its relatively elevated levels of caproic, caprylic, capric and mediumchain fatty acids, which have been used for the treatment of a variety of malabsorption syndromes (Park, 1994;Alférez et al, 2001), and because of its smaller fat globule size, which makes goat milk more easily digestible than cow milk (Jandal, 1996).…”

Milk quality characteristics from Greek indigenous goats

“…Three of the MCT (C6-C14) have actually been named after goats, because of their predominance in goat milk. Caproic, capric and caprylic acids have become established medical treatments for an array of clinical disorders (Schwabe et al, 1964;Greenberger and Skillman, 1969;Kalser, 1971;Tantibhedhyangkul and Hashim, 1975;Alférez et al, 2001). Goat milk exceeds cow milk in monounsaturated (MUFA), polyunsaturated fatty acids (PUFA), and medium chain FA, which all are known as beneficial to human health, especially for cardiovascular conditions.…”

The Effect of Fatty Acids in Goat Milk on Health

“…Goat milk exceeds cow and sheep milk in monounsaturated, polyunsaturated fatty acids, and medium chain triglycerides, which all are known to be beneficial for human health, especially for cardiovascular conditions. Capric, caprylic acids and medium chain triglycerides have become established medical treatments for an array of clinical disorders, including malabsorption syndromes, chyluria, steatorrhea, hyperlipoproteinemia, intestinal resection, premature infant feeding, non-thriftiness of children, infant malnutrition, epilepsy, cystic fibrosis, coronary by-pass, and gallstones, because of their unique metabolic ability to provide direct energy instead of being deposited in adipose tissues, and because of their actions of lowering serum cholesterol, inhibiting and limiting cholesterol deposition (Alferez et al, 2001;Greenberger & Skillman, 1969;Kalser, 1971;Schwabe et al, 1964;Tantibhedhyanangkul & Hashim, 1978).…”