Digestion property and synergistic effect on biological activity of purple rice ( Oryza sativa L.) anthocyanins subjected to a simulated gastrointestinal digestion in vitro

Sun, Dan; Huang, Shiqi; Cai, Shengbao; Cao, Jun; Han, Peng

doi:10.1016/j.foodres.2015.10.029

Cited by 89 publications

(61 citation statements)

References 41 publications

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“…This was an expected outcome as the stability of acylated anthocyanins towards pH change is shown to be higher than non-acylated counterparts (Kammerer, Carle, & Schieber, 2004). The degradation of anthocyanins during simulated intestinal digestion is in line with previously published studies (Correa-Betanzo et al, 2014;Sun, Huang, Cai, Cao, & Han, 2015). The high loss of anthocyanins may be related to the fact that in aqueous solution, anthocyanins undergo structural re-arrangements in response to changes in pH in four molecular structures: quinoidal base (blue), flavylium cation (red), carbinol (colorless) and chalcone (yellowish) forms.…”

Section: Anthocyaninssupporting

confidence: 89%

Black carrot pomace as a source of polyphenols for enhancing the nutritional value of cake: An in vitro digestion study with a standardized static model

Kamiloglu

Özkan

Isik

et al. 2017

LWT

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Section: Anthocyaninssupporting

confidence: 89%

Black carrot pomace as a source of polyphenols for enhancing the nutritional value of cake: An in vitro digestion study with a standardized static model

Kamiloglu

Özkan

Isik

et al. 2017

LWT

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“…Phenolic compounds are important secondary plant metabolites that determine the sensory and nutritional qualities of fruits, vegetables, and other plant products. Phenolics have received attention in recent years because of their antioxidant [5], antimicrobial [6], antimelanogenesis [7], hepatoprotective [8] and anti-inflammatory [9] effects. Studies suggest that a large number of phenolic extracts from plants, including mulberry leaf [10], Pistachia lentiscus L. leaves from Algeria [11], Astilboides tabularis [12], mate tea [13], Korean sorghum [14], Pongamia pinnata Pierreseeds [15], and Pseuduvaria monticola bark [16], demonstrate anti-diabetic properties.…”

Section: Introductionmentioning

confidence: 99%

Anti-Diabetic Effects of Phenolic Extract from Rambutan Peels (Nephelium lappaceum) in High-Fat Diet and Streptozotocin-Induced Diabetic Mice

Guo

Sun

et al. 2017

Nutrients

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Recent studies have shown that rambutan peel phenolic (RPP) extract demonstrate high antioxidant and antiglycation activities in vitro and in vivo. This study further evaluated the anti-diabetic activity of RPP in a mouse model of Type II diabetes induced by streptozotocin combined with high-fat diet. Results showed that RPP increased the body weight and reduced the fasting blood glucose level of the diabetic mice. RPP significantly reduced the serum levels of total cholesterol, triglyceride, creatinine, and glycated serum protein in diabetic mice in a dose-dependent manner. Glycogen content in mice liver was recovered by RPP, which further increased the activity of superoxide dismutase and glutathione peroxidase and reduced lipid peroxidation in diabetic mice. Histological analysis showed that RPP effectively protected the tissue structure of the liver, kidney, and pancreas. In addition, RPP decreased the mesangial index and inhibited the expression of TGF-β in the kidney of diabetic mice.

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“…The DPPH radical scavenging activities of the fractions and compounds were evaluated according to a modified reported method [33]. The samples were dissolved in 70% ethanol.…”

Section: Methodsmentioning

confidence: 99%

“…The ABTS radical scavenging activities of the fractions and compounds were determined as previously described [33]. The ABTS radical scavenging activities were calculated using the following formula: ABTS scavenged (%) =

\frac{false(false(A 0 - A 0^{'} false) - false(A 1 - A 1^{'} false) false)}{false(A 0 - A 0^{'} false)}

× 100%, where A1, A1′, A0, and A0′ represent the absorbance of sample solutions and ABTS working solution, the absorbance of sample solutions and distilled water, the absorbance of 70% ethanol and ABTS working solution, and the absorbance of 70% ethanol and distilled water, respectively.…”

Section: Methodsmentioning

confidence: 99%

Optimization of extraction for Anemarrhena asphodeloides Bge. using silica gel‐based vortex‐homogenized matrix solid‐phase dispersion and rapid identification of antioxidant substances

Sun

et al. 2020

J of Separation Science

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A novel and simple method was established for the extraction and determination of seven compounds in Anemarrhena asphodeloides Bge. using silica gel-based vortex-homogenized matrix solid-phase dispersion and ultra-high performance liquid chromatography quadrupole-time of-flight mass spectrometer. The conditions for the extraction were optimized. Silica gel was used as the dispersant, 50% methanol-water was selected as an elution solvent and the grinding time was 3 min. Compared with the traditional ultrasonic-assisted extraction, the developed method was rapid and efficient. In order to screen potential antioxidants, extract dealing with the optimized method was applied to a polyamide chromatography column and a D-101 macroporous resin column. Fr.2.2 showed the highest antioxidant activities with the most content of flavonoid. A total of 25 peaks were identified from the active fraction. A 2,2 ′ -diphenyl-1-picrylhydrazyl ultra-high performance liquid chromatography coupled with mass spectrometry approach was adopted for the rapid and exact screening and identification of antioxidant compounds. It indicated that flavonoids exhibited potential antioxidant activities. The antioxidant activities of nine monomeric compounds in vivo were tested. Structure-activity relationships were discussed.Five flavonoids with the concentration of 500 µg/mL would reduce the oxidative stress of PC12 cells that were induced with 2,2 ′ -azobis[2-methylpropionamidine] dihydrochloride.

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Digestion property and synergistic effect on biological activity of purple rice ( Oryza sativa L.) anthocyanins subjected to a simulated gastrointestinal digestion in vitro

Cited by 89 publications

References 41 publications

Black carrot pomace as a source of polyphenols for enhancing the nutritional value of cake: An in vitro digestion study with a standardized static model

Black carrot pomace as a source of polyphenols for enhancing the nutritional value of cake: An in vitro digestion study with a standardized static model

Anti-Diabetic Effects of Phenolic Extract from Rambutan Peels (Nephelium lappaceum) in High-Fat Diet and Streptozotocin-Induced Diabetic Mice

Optimization of extraction for Anemarrhena asphodeloides Bge. using silica gel‐based vortex‐homogenized matrix solid‐phase dispersion and rapid identification of antioxidant substances

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