Diffuse lipomatosis of thyroid with hyperthyroidism

Pradeep, P. V.; Kumar, Ramaiah Vinay; Ragavan, M; Ramakrishna, Baddukonda Appala

doi:10.4103/0022-3859.62430

Cited by 10 publications

(11 citation statements)

References 7 publications

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“…Although there are no clear guidelines to establish a diagnosis of thyroid lipomatosis with this method, the cytological findings are specific enough to exclude anaplastic carcinoma and thyroid lymphoma (9).…”

Section: Discussionmentioning

confidence: 99%

Thyroid lipomatosis in a 36-year-old patient with rheumatoid arthritis and a kidney transplant

Bell

Sosa

Jaén

et al. 2016

Endocrinology, Diabetes &Amp; Metabolism Case Reports

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SummaryThyroid lipomatosis is a rare disease, as a total of 20 cases have been described in the literature. It is characterized by diffuse infiltration of the stroma by mature adipose tissue and by progressive growth that produces different degrees of compressive symptoms. Our aim is to present the case of a 36-year-old woman who consulted because of dyspnea caused by a multinodular goiter. She underwent surgery with the presumptive diagnosis of a malignant neoplasia, but the pathological examination of the surgical specimen established the diagnosis of thyroid lipomatosis.Learning points Thyroid lipomatosis is a rare, benign disease characterized by diffuse infiltration of the stroma by mature adipose tissue.The pathophysiology of diffuse proliferation of adipose tissue in the thyroid gland is unclear.Thyroid lipomatosis is clinically manifested by a progressive enlargement of the thyroid that can involve the airway and/or upper gastrointestinal tract, producing dyspnea, dysphagia, and changes in the voice.Given the rapid growth of the lesion, the two main differential diagnoses are anaplastic carcinoma and thyroid lymphoma.Imaging studies may suggest a differential diagnosis, but a definitive diagnosis generally requires histopathological confirmation after a thyroidectomy.

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Section: Discussionmentioning

confidence: 99%

Thyroid lipomatosis in a 36-year-old patient with rheumatoid arthritis and a kidney transplant

Bell

Sosa

Jaén

et al. 2016

Endocrinology, Diabetes &Amp; Metabolism Case Reports

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“…Postoperative fatty tissue infiltration is noted microscopically between the thyroid follicles on pathology materials (1). Preoperatively, fine-needle aspiration cytology may suggest a diagnosis of thyroid lipomatosis based on an abundance of fat cells in the smear (9). Additionally, computerized tomography of the thyroid may reveal low attenuation components with negative Hounsfield units (3).…”

Section: Discussionmentioning

confidence: 99%

Thyroid Lipomatosis

et al. 2012

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Thyroid lipomatosis is a rare condition characterized by the presence of abundant mature adipose tissue in the thyroid gland. We herein report the case of a 43-year-old man with chronic renal failure caused by amyloidosis presenting with an asymmetrically enlarging thyroid gland. The patient's thyroid hormone levels were normal, and test results for thyroid autoantibodies were negative. A thyroid scan showed diffuse uptake of the radioisotope with a cold area in the left lobe. The pathology of the thyroidectomy material indicated thyroid lipomatosis, and minimal amyloid staining was noted around the thyroid follicles. Thyroid lipomatosis should therefore be kept in mind when making a differential diagnosis of fatty infiltration of amyloid goiter.

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“…The thyroid hormone level is frequently normal; in contrast to other series that of the Ben Gamra and Pradeep reported some cases with hyperthyroidism [12] [13].…”

Section: Discussionmentioning

confidence: 63%

“…Adenolipoma and intrathyroid fat-containing masses were easily excluded, because these rare entities appear as focal nodules, well circumscribed within an otherwise normal gland [7]. However, liposarcoma of the thyroid is rare, the rapid clinical course and local invasion suggests the diagnosis [12]. Amyloid goiter, which often contains fat cells, is not difficult to distinguish from thyrolipoma or thyrolipomatosis as the amyloid deposition is readily evident and can be confirmed with special stains [1].…”

Section: Discussionmentioning

confidence: 99%

Diffuse Lipomatosis of Thyroid—Case Report

Jahid¹,

Amine²,

Chad³

2018

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Diffuse lipomatosis of thyroid gland is very rare disease, characterized by diffuse proliferation of adipose tissue in the thyroid gland, the pathophysiology of adipose tissue infiltration in the thyroid gland remains unknown. We report a case of a 55-year-old female who presented 6 months ago a dysphonia, ultrasound of the neck revealed the presence diffuse goiter with heterogeneous echogenicity, her thyroid hormone levels were normal, thyroid isotope scanning showed heterogeneous uptake of radioactivity and coexistence of cold and hot nodules. The patient underwent total thyroidectomy. Histological study concluded to the diagnosis of diffuse lipomatosis of thyroid gland.

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Diffuse lipomatosis of thyroid with hyperthyroidism

Cited by 10 publications

References 7 publications

Thyroid lipomatosis in a 36-year-old patient with rheumatoid arthritis and a kidney transplant

Thyroid lipomatosis in a 36-year-old patient with rheumatoid arthritis and a kidney transplant

Thyroid Lipomatosis

Diffuse Lipomatosis of Thyroid—Case Report

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