Diffuse Calcification of the Airways

Wright, Joanne L.; Jones, Edward

doi:10.1038/modpathol.3880378

Cited by 8 publications

(6 citation statements)

References 8 publications

(9 reference statements)

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“…2 These can all arise in the setting of chronic renal insufficiency and secondary or tertiary hyperparathyroidism, which favors the deposition of calcium salts in the viscera. 1,4 Microscopically, calcium deposition occurs in the alveolar epithelial basement membranes, although it can also happen in the alveolar-capillary walls, bronchial walls, and bronchioles. They can be linear or granular, and larger accumulations happen where alveoli open into alveolar ducts.…”

Section: Discussionmentioning

confidence: 99%

“…3 It is known that peripheral neuropathy is produced in chronic obstructive pulmonary disease and that it is characteristically caused by long-term exposure to cigarette smoke. 4 Furthermore, experimental results suggest that chronic nicotine increases hypersensitivity after peripheral nerve injury. 5 In addition, it has been experimentally demonstrated that repeated myelin degradation and axonal degeneration after injury, which is called Wallerian degeneration, is accompanied by Schwann cell proliferation.…”

Section: A Plausible Neural Origin Through Chronic Tobacco Mucosa Irr...mentioning

confidence: 99%

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Patient With Metastatic Airway Calcification and Hypercalcemia Due to Secondary Hyperparathyroidism

Diaz-Churion

Lee‐Mateus

Mirzan

et al. 2023

Journal of Bronchology &Amp; Interventional Pulmonology

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Section: Discussionmentioning

confidence: 99%

Section: A Plausible Neural Origin Through Chronic Tobacco Mucosa Irr...mentioning

confidence: 99%

Patient With Metastatic Airway Calcification and Hypercalcemia Due to Secondary Hyperparathyroidism

Diaz-Churion

Lee‐Mateus

Mirzan

et al. 2023

Journal of Bronchology &Amp; Interventional Pulmonology

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“…Tracheobronchopathia osteochondroplastica usually presents as cartilaginous spurs or as endobronchial masses that may cause distortion or abnormal narrowing of the airway, and is typically discovered as an incidental finding on chest CT or bronchoscopy. [5][6][7] Only in rare cases does tracheobronchopathia osteochondroplastica cause symptomatic luminal obstruction requiring endobronchial debridement.…”

Section: Discussionmentioning

confidence: 99%

A Bronchoscopic Oddity

Bhadra

Butnor²,

Davis

2010

Journal of Bronchology &Amp; Interventional Pulmonology

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Tracheobronchial amyloidosis is a rare disorder of unknown cause associated with the extracellular deposition of amyloid protein in a characteristic spatial structure of β-sheet fibrils assembled into bundles. We present a case that represents the nodular form of tracheobronchial amyloidosis, which is the least common form of pulmonary amyloidosis with less than 20 cases reported so far. Patients with tracheobronchial amyloidosis may present with symptoms of dyspnea, localized wheezing, cough, hemoptysis, or recurrent pneumonias. The mainstay of the therapy is debridement of the symptomatic luminal obstruction with neodymium-doped yttrium aluminium garnet laser therapy. Other treatment strategies include airway stenting, external beam radiation therapy, bypass tracheostomy, or open surgical resection.

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“…Although rare, it is important to pay attention for tracheobronchial calcification on preoperative imaging as it may complicate the airway anastomosis during the LTx procedure. Tracheobronchial calcification is an uncommon radiological finding reported to be associated with old age, females, hypercalcemia, and sarcoidosis (32)(33)(34). Extensive calcification of the main bronchi may cause fragmentation of the airway cartilage during manipulation, dissection, or performing the anastomosis.…”

Section: Calcified Airwaymentioning

confidence: 99%

Bilateral sequential lung transplantation: technical aspects

Elgharably¹,

Javorski²,

McCurry³

2021

J Thorac Dis

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The surgical technique for lung transplantation has evolved dramatically over the last three decades. Significant improvements in short term outcomes in the early years of lung transplantation were due, in large part, to techniques developed to reduce airway anastomotic complications in single lung transplantation. Following development of the technique of en bloc double lung transplantation, evolution to the bilateral sequential technique further reduced airway complications for double lung transplantation.More recently, some programs have utilized the en bloc double lung transplant technique with bronchial artery revascularization to aid airway healing and potentially improve short-and long-term outcomes. The experience with bronchial artery revascularization remains limited to a few series, with the technique having not been widely adopted by most lung transplant programs. With the implementation of priority allocations schemes in many countries, patients with higher risk profiles are being prioritized for transplantation which results in more complex procedures in fragile recipients with multiple comorbidities. This includes the increased need for concomitant cardiac procedures as well as performing lung transplantation after prior cardiothoracic surgery. Different surgical approaches have been described for bilateral sequential lung transplantation with or without intra-operative mechanical circulatory support (MCS), such as sternotomy, clamshell (bilateral anterior thoracotomies with transverse sternotomy), and bilateral thoracotomy incisions.Herein, we aim, not only to describe the various surgical approaches for double lung transplantation, but to provide a comprehensive review of other aspects related to the recipient pathology and different anatomical variants as well as handling technical challenges that might be encountered during the procedure.

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Diffuse Calcification of the Airways

Cited by 8 publications

References 8 publications

Patient With Metastatic Airway Calcification and Hypercalcemia Due to Secondary Hyperparathyroidism

Patient With Metastatic Airway Calcification and Hypercalcemia Due to Secondary Hyperparathyroidism

A Bronchoscopic Oddity

Bilateral sequential lung transplantation: technical aspects

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