Diffuse alveolar hemorrhage - review of an interstitial lung disease clinic

Afonso, Margarida; Alfaro, Tiago M.; Fernandes, Vânia; Cemlyn-Jones, Jessica

doi:10.1183/1393003.congress-2017.pa3862

Cited by 2 publications

(2 citation statements)

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“…Однако такое сочетание (в ситуации иммунологического генеза кровотечения) бывает, по данным тех же авторов, лишь у 46,1% больных. К примеру, кровохарканье как наиболее наглядный симптом в реальной практике встречается всего в 30-40% ДАК [29][30][31]. Его появлению в значительной степени препятствует фактор высокой емкости альвеолярного депонирования крови [2].…”

Section: обзорunclassified

Pulmonary embolism and diffuse alveolar bleeding: combination options and therapy features

Tretyakov

Юрьевич²,

Раденска-Лоповок

et al. 2021

Terapevticheskii arkhiv

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The analysis of the mechanisms of the formation of a rare clinical combination of pulmonary embolism (PE) and diffuse alveolar hemorrhage (DAH), which are complications of systemic vasculitis associated with antibodies to the cytoplasm of neutrophils (primarily granulomatosis with polyangiitis), systemic lupus erythematosus and secondary antiphlogistic syndrome primary antiphospholipid syndrome and Goodpastures syndrome. Taking into account the chronological sequence of the occurrence of PE and DAH, 3 variants of the onset of these potentially fatal additions to the underlying disease were considered: the anticipatory DAH development of PE, delayed from DAH PE and joint (within 24 hours) formation of PE and DAH. A review of single descriptions of such a combination of complications of granulomatosis with polyangiitis is carried out, criteria are indicated, a working classification of severity is given and, taking this into account, a modern program of therapy for DAH as an independent event and in combination with PE.

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Section: обзорunclassified

Pulmonary embolism and diffuse alveolar bleeding: combination options and therapy features

Tretyakov

Юрьевич²,

Раденска-Лоповок

et al. 2021

Terapevticheskii arkhiv

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“…Alveolar hemorrhage presentation could be misdiagnosed by other diseases such as acute pulmonary edema, a condition commonly seen in patients with ACS. 5 Most cases of DAH are caused by capillaritis associated with systemic autoimmune diseases such as anti-neutrophil cytoplasmic antibody-associated vasculitis, anti-glomerular basement membrane disease, and systemic lupus erythematosus, but DAH may also result from coagulation disorders, drugs, inhaled toxins, or transplantation. 6 …”

Section: Introductionmentioning

confidence: 99%

Diffuse alveolar hemorrhage; An under-diagnosed and rare complication of glycoprotein IIb/IIIa inhibitors

Hekmat

Vahabi

Shojaeifard

et al. 2022

J Cardiovasc Thorac Res

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Glycoprotein IIb/IIIa inhibitors play a key role in the treatment of patients who have acute coronary syndromes and undergone percutaneous coronary intervention. However, its serious complication is diffused alveolar hemorrhage. A 73-year-old diabetic woman presented with chest pain and dynamic ST elevation in ECG and positive troponin. She had occlusion in two coronary arteries and underwent percutaneous coronary intervention. The eptifibatide was administered. After hours, she showed respiratory symptoms, as well as drop of blood pressure and hemoglobin. All differential diagnoses suggested for her clinical presentation were evaluated, and finally, on the sixth day diffuse alveolar hemorrhage was diagnosed. Although respiratory symptoms such as hemoptysis and dyspnea may occur as complications of pulmonary edema and/or pneumonia, assumed clinical suspicion for pulmonary hemorrhage leading to early detection of it. Moreover, there is no definitive guideline for decreased bleeding complications and treatment of alveolar hemorrhage caused by glycoprotein IIb/IIIa receptor inhibitors.

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Diffuse alveolar hemorrhage - review of an interstitial lung disease clinic

Cited by 2 publications

References 0 publications

Pulmonary embolism and diffuse alveolar bleeding: combination options and therapy features

Pulmonary embolism and diffuse alveolar bleeding: combination options and therapy features

Diffuse alveolar hemorrhage; An under-diagnosed and rare complication of glycoprotein IIb/IIIa inhibitors

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