Differentiation of Lung Metastases Originated From Different Primary Tumors Using Radiomics Features Based on CT Imaging

Shang, Hui; Li, Jizhen; Jiao, Tianyu; Fang, Caiyun; Li, Kejian; Yin, Di; Zeng, Qingshi

doi:10.1016/j.acra.2022.04.008

Cited by 9 publications

(6 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The model developed by the group ultimately achieved a robust predictive capability (validation area under the curve: 0.922) 31 . This approach also has promises in further radiographically discriminating PM from primary lung tumors 34,35 …”

Section: Discussionmentioning

confidence: 95%

See 1 more Smart Citation

Do resected colorectal cancer patients need early chest imaging? Impact of clinicopathologic characteristics on time to development of pulmonary metastases

Deboever,

Bayley,

Eisenberg

et al. 2023

Journal of Surgical Oncology

View full text Add to dashboard Cite

Background and ObjectivesFor patients with colorectal cancer (CRC), the lung is the most common extra‐abdominal site of distant metastasis. However, practices for chest imaging after colorectal resection vary widely. We aimed to identify characteristics that may indicate a need for early follow‐up imaging.MethodsWe retrospectively reviewed charts of patients who underwent CRC resection, collecting clinicopathologic details and oncologic outcomes. Patients were grouped by timing of pulmonary metastases (PM) development. Analyses were performed to investigate odds ratio (OR) of PM diagnosis within 3 months of CRC resection.ResultsOf 1600 patients with resected CRC, 233 (14.6%) developed PM, at a median of 15.4 months following CRC resection. Univariable analyses revealed age, receipt of systemic therapy, lymph node ratio (LNR), lymphovascular and perineural invasion, and KRAS mutation as risk factors for PM. Furthermore, multivariable regression showed neoadjuvant therapy (OR: 2.99, p < 0.001), adjuvant therapy (OR: 6.28, p < 0.001), LNR (OR: 28.91, p < 0.001), and KRAS alteration (OR: 5.19, p < 0.001) to predict PM within 3 months post‐resection.ConclusionsWe identified clinicopathologic characteristics that predict development of PM within 3 months after primary CRC resection. Early surveillance in such patients should be emphasized to ensure timely identification and treatment of PM.

show abstract

Section: Discussionmentioning

confidence: 95%

“…33 31 This approach also has promises in further radiographically discriminating PM from primary lung tumors. 34,35 There are limitations associated with this work. First, the review of characteristics was performed in a retrospective manner, and thus bias may be present, despite our databases being prospectively maintained.…”

Section: Discussionmentioning

confidence: 99%

Do resected colorectal cancer patients need early chest imaging? Impact of clinicopathologic characteristics on time to development of pulmonary metastases

Deboever,

Bayley,

Eisenberg

et al. 2023

Journal of Surgical Oncology

View full text Add to dashboard Cite

show abstract

“…Shang et al [ 76 ] explored the role of radiomics to differentiate lung metastatic nodules from breast, colorectal and renal cancer by means of MDCT radiomics features. They performed a retrospective analysis including 252 LM from 78 patients, which were randomly divided into a training cohort ( n = 176) and a test cohort ( n = 76).…”

Section: Discussionmentioning

confidence: 99%

“…Three studies (37.5%) [ 55 , 56 , 68 ] evaluated the potential applicability of radiomics models in a clinical setting by means of DCA. In most studies (75%) [ 71 , 72 , 74 , 75 , 76 , 77 ] multiple segmentations were performed to evaluate the robustness of radiomics features in relation to segmentation variability.…”

Section: Discussionmentioning

confidence: 99%

Radiomics in Lung Metastases: A Systematic Review

Gabelloni

Faggioni

Fusco

et al. 2023

JPM

View full text Add to dashboard Cite

Due to the rich vascularization and lymphatic drainage of the pulmonary tissue, lung metastases (LM) are not uncommon in patients with cancer. Radiomics is an active research field aimed at the extraction of quantitative data from diagnostic images, which can serve as useful imaging biomarkers for a more effective, personalized patient care. Our purpose is to illustrate the current applications, strengths and weaknesses of radiomics for lesion characterization, treatment planning and prognostic assessment in patients with LM, based on a systematic review of the literature.

show abstract

“…However, there are currently few percutaneous puncture procedure path planning systems specifically designed for pulmonary masses. Most systems require interaction with clinicians for semi-automatic path selection (Cifci 2023, Mkindu et al 2023, Shang et al 2023.…”

Section: Introductionmentioning

confidence: 99%

Path planning algorithm for percutaneous puncture lung mass biopsy procedure based on the multi-objective constraints and fuzzy optimization

Zhang,

Han

et al. 2024

Phys. Med. Biol.

View full text Add to dashboard Cite

Objective. The percutaneous puncture lung mass biopsy procedure, which relies on preoperative CT images, is considered the gold standard for determining the benign or malignant nature of lung masses. However, the traditional lung puncture procedure has several issues, including long operation times, a high probability of complications, and high exposure to CT radiation for the patient, as it relies heavily on the surgeon's clinical experience. Approach. To address these problems, a multi-constrained objective optimization model based on clinical criteria for the percutaneous puncture lung mass biopsy procedure has been proposed. Additionally, based on fuzzy optimization, a multidimensional spatial Pareto front algorithm has been developed for optimal path selection. The algorithm finds optimal paths, which are displayed on 3D images, and provides reference points for clinicians' surgical path planning. Main results. To evaluate the algorithm's performance, 25 data sets collected from the Second People's Hospital of Zigong were used for prospective and retrospective experiments. The results demonstrate that 92% of the optimal paths generated by the algorithm meet the clinicians' surgical needs. Significance. The algorithm proposed in this paper is innovative in the selection of mass target point, the integration of constraints based on clinical standards, and the utilization of multi-objective optimization algorithm. Comparison experiments have validated the better performance of the proposed algorithm. From a clinical standpoint, the algorithm proposed in this paper has a higher clinical feasibility of the proposed pathway than related studies, which reduces the dependency of the physician's expertise and clinical experience on pathway planning during the percutaneous puncture lung mass biopsy procedure.

show abstract

Differentiation of Lung Metastases Originated From Different Primary Tumors Using Radiomics Features Based on CT Imaging

Cited by 9 publications

References 18 publications

Do resected colorectal cancer patients need early chest imaging? Impact of clinicopathologic characteristics on time to development of pulmonary metastases

Do resected colorectal cancer patients need early chest imaging? Impact of clinicopathologic characteristics on time to development of pulmonary metastases

Radiomics in Lung Metastases: A Systematic Review

Path planning algorithm for percutaneous puncture lung mass biopsy procedure based on the multi-objective constraints and fuzzy optimization

Contact Info

Product

Resources

About