Differentiation of benign from malignant solid breast masses: comparison of two-dimensional and three-dimensional shear-wave elastography

Lee, Sang Ho; Chang, Jung Min; Kim, Won Hwa; Bae, Min Sun; Cho, Nariya; Yi, Ann; Koo, Hye Ryoung; Kim, Seung Ja; Kim, Jin Joo; Moon, Woo Kyung

doi:10.1007/s00330-012-2686-9

Cited by 103 publications

(88 citation statements)

References 26 publications

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“…In the present work, the most useful and reproducible measure was the mass/fat elasticity ratio, unlike what was found by Wang et al (P < 0.01 vs. P = 0.088) (18). Breast fat tissue shows minimal elastographic variability, and the elasticity values are very low, supporting the use of fat tissue stiffness as a comparator (16,19). Probe compression raises elastographic values, increasing the likelihood of overdiagnosis.…”

Section: Discussioncontrasting

confidence: 44%

Use of shear wave elastography to differentiate benign and malignant breast lesions

Olgun

Korkmazer²,

Kılıç³

et al. 2014

Diagn Interv Radiol

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ORIGINAL ARTICLE PURPOSE We aimed to determine the correlations between the elasticity values of solid breast masses and histopathological findings to define cutoff elasticity values differentiating malignant from benign lesions. MATERIALS and METHODSA total of 115 solid breast lesions of 109 consecutive patients were evaluated prospectively using shear wave elastography (SWE). Two orthogonal elastographic images of each lesion were obtained. Minimum, mean, and maximum elasticity values were calculated in regions of interest placed over the stiffest areas on the two images; we also calculated mass/fat elasticity ratios. Correlation of elastographic measurements with histopathological results were studied. RESULTS Eighty-three benign and thirty-two malignant lesions were histopathologically diagnosed. The minimum, mean, and maximum elasticity values, and the mass/fat elasticity ratios of malignant lesions, were significantly higher than those of benign lesions. The cutoff value was 45.7 kPa for mean elasticity (sensitivity, 96%; specificity, 95%), 54.3 kPa for maximum elasticity (sensitivity, 95%; specificity, 94%), 37.1 kPa for minimum elasticity (sensitivity, 96%; specificity, 95%), and 4.6 for the mass/fat elasticity ratio (sensitivity, 97%; specificity, 95%). CONCLUSION SWE yields additional valuable quantitative data to ultrasonographic examination on solid breast lesions. SWE may serve as a complementary tool for diagnosis of breast lesions. Long-term clinical studies are required to accurately select lesions requiring biopsy.

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Section: Discussioncontrasting

confidence: 44%

Use of shear wave elastography to differentiate benign and malignant breast lesions

Olgun

Korkmazer²,

Kılıç³

et al. 2014

Diagn Interv Radiol

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“…In the present study, the additional use of SWE to conventional US reduced the rate of benign lesion biopsy by 46.0% to 85.7%. This result is similar to those others have reported (8,28,29). In BI-RADS category 3 cases, biopsies are frequently performed at the request of the clinician or patient.…”

Section: Discussionsupporting

confidence: 81%

Clinical Application of Shear Wave Elastography in Breast Masses

et al. 2016

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“…Based on no loss in accuracy, EMAX, EMEANH and SD were further improved in sensitivity when orthogonal acquisitions conducted. Though the cut-off values are different [1] and some are higher than the values in this study [3,4,[11][12][13][14][15], the diagnostic performances are almost fair [3,4,[11][12][13][14][15][16][17][18]. It can be resulted by high rate of DCIS (6/41 in malignant group) and hard rule of avoiding pressure (images with apparent artefacts were excluded) in this study.…”

Section: Discussioncontrasting

confidence: 61%

Can continuous scans in orthogonal planes improve diagnostic performance of shear wave elastography for breast lesions?

Yang¹,

Peng²,

Zhao³

et al. 2015

THC

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Abstract. BACKGROUND: Static shear wave elastography (SWE) is used to detect breast lesions, but slice and plane selections result in discrepancies. OBJECTIVE: To evaluate the intraobserver reproducibility of continuous SWE, and whether quantitative elasticities in orthogonal planes perform better in the differential diagnosis of breast lesions. METHOD: One hundred and twenty-two breast lesions scheduled for ultrasound-guided biopsy were recruited. Continuous SWE scans were conducted in orthogonal planes separately. Quantitative elasticities and histopathology results were collected. Reproducibility in the same plane and diagnostic performance in different planes were evaluated. RESULTS: The maximum and mean elasticities of the hardest portion, and standard deviation of whole lesion, had high inter-class correlation coefficients (0.87 to 0.95) and large areas under receiver operation characteristic curve (0.887 to 0.899). Without loss of accuracy, sensitivities had increased in orthogonal planes compared with single plane (from 73.17% up to 82.93% at most). Mean elasticity of whole lesion and lesion-to-parenchyma ratio were significantly less reproducible and less accurate. CONCLUSION: Continuous SWE is highly reproducible for the same observer. The maximum and mean elasticities of the hardest portion and standard deviation of whole lesion are most reliable. Furthermore, the sensitivities of the three parameters are improved in orthogonal planes without loss of accuracies.

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Differentiation of benign from malignant solid breast masses: comparison of two-dimensional and three-dimensional shear-wave elastography

Abstract: Two-dimensional and 3D SWE performed equally in distinguishing benign from malignant masses and both techniques improved the specificity of B-mode ultrasound.

Cited by 103 publications

References 26 publications

Use of shear wave elastography to differentiate benign and malignant breast lesions

Use of shear wave elastography to differentiate benign and malignant breast lesions

Clinical Application of Shear Wave Elastography in Breast Masses

Can continuous scans in orthogonal planes improve diagnostic performance of shear wave elastography for breast lesions?

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