Differentiating Childhood-Onset Schizophrenia From Psychotic Mood Disorders

Calderoni, Dario; Wudarsky, Marianne; Bhangoo, Robinder K.; Dell, Mary Lynn; Nicolson, Rob; Hamburger, Susan; Gochman, Peter; Lenane, Marge; Rapoport, Judith L.; Leibenluft, Ellen

doi:10.1097/00004583-200110000-00013

Cited by 43 publications

(26 citation statements)

References 35 publications

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“…Calderoni et al [38] had a team of two child and adolescent psychiatrists and one adult psychiatrist blindly re-evaluate the structured diagnostic interviews of 33 pediatric patients who were excluded from a COS study because the research team had originally diagnosed a mood disorder. Fourteen patients had psychotic major depression, 15 had bipolar disorder, and four had schizoaffective disorder.…”

Section: Psychotic Major Depressionmentioning

confidence: 99%

Psychosis in children with velocardiofacial syndrome (22q11.2 deletion syndrome)

Jolin

Weller²,

Weller

2009

Curr Psychiatry Rep

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Velocardiofacial syndrome, now known as 22q11.2 deletion syndrome (22qDS), is estimated to affect more than 700 children born in the United States each year. Some clinical studies have found increased rates of schizophrenia in adults with 22qDS. However, these studies have been limited by small sample size and possible ascertainment bias. The psychiatric disorders most commonly reported in children and adolescents with 22qDS have been attention-deficit/hyperactivity disorder, oppositional defiant disorder, anxiety disorders, and major depression. Psychotic symptoms have been observed in 14% to 28% of children with 22qDS, but their clinical significance remains uncertain. A 5-year follow-up study of 22qDS children who reported psychotic symptoms at baseline found they had an increased risk for a subsequent psychotic disorder. Thus, a broad differential diagnosis should be considered when 22qDS children present with psychotic symptoms. Longitudinal studies are needed to better understand the full extent of the psychopathology associated with 22qDS.

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Section: Psychotic Major Depressionmentioning

confidence: 99%

Psychosis in children with velocardiofacial syndrome (22q11.2 deletion syndrome)

Jolin

Weller²,

Weller

2009

Curr Psychiatry Rep

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“…Interest in bipolar disorders in adolescents has increased, with several retrospective studies revealing that 20%-60% of adults with BD had their first symptoms before the age of 20 years (Joyce, 1984;Lish et al, 1994;Perlis et al, 2004). The phenomenology of acute manic or mixed episodes in adolescents can be summarized as follows: a higher frequency of mixed episodes than purely manic ones, more frequent aggression and irritability (McElroy et al, 1997;Patel et al, 2006), the presence of psychotic signs in 30%-60% of the cases (which can lead to diagnosis difficulties (Calderoni et al, 2001;Carlson et al, 1994;Kowatch et al, 2005;Soutullo et al, 2005)), high rates of comorbidities and a higher likelihood of a rapid cycling profile (Schurhoff et al, 2000;Birmaher et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Diagnostic transition towards schizophrenia in adolescents with severe bipolar disorder type I: An 8-year follow-up study

Consoli¹,

Brunelle²,

Bodeau³

et al. 2014

Schizophrenia Research

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“…In a study by Calderoni et al [26], eight (57%) of 14 children and adolescents with MDD with psychosis and three (20%) of 15 patients with bipolar disorder and psychosis had comorbid anxiety disorders. Attention deficit hyperactivity disorder also was comorbid in seven of the 15 patients with bipolar disorder and in one patient with MDD.…”

Section: Differential Diagnosis Of Hallucinationsmentioning

confidence: 96%

Hallucinations in children and adolescents

Sosland

Edelsohn

2005

Curr Psychiatry Rep

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Clinicians need to consider a wide range of differential diagnoses when children and adolescents present with hallucinations. This includes considering whether it is a developmentally normal phenomenon or if there is a psychiatric, medical, or neurologic diagnosis. Nonpsychotic children with hallucinations can be differentiated from psychotic children. Nonpsychotic children who are at risk (or prodromal) for future psychosis can be differentiated from nonprodromal healthier children. We examine the epidemiology, prognosis, and neurobiological research. Lastly, we discuss treatment approaches, including medication and cognitive behavioral therapy.

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Differentiating Childhood-Onset Schizophrenia From Psychotic Mood Disorders

Cited by 43 publications

References 35 publications

Psychosis in children with velocardiofacial syndrome (22q11.2 deletion syndrome)

Psychosis in children with velocardiofacial syndrome (22q11.2 deletion syndrome)

Diagnostic transition towards schizophrenia in adolescents with severe bipolar disorder type I: An 8-year follow-up study

Hallucinations in children and adolescents

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