Differential Taste Sensitivities in Duodenal and Gastric Ulcer Patients

Kaplan, Abnold R.; Fischer, Roland; Glanville, Edward V.; Powell, Wilma; Kamionkowski, Mario D.; Fleshler, Bertram

doi:10.1016/s0016-5085(19)34675-x

Cited by 21 publications

(1 citation statement)

References 13 publications

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“…There have been reports of associations or lack of associations between PTC taste status and diseases and traits not directly related to taste. These include diabetes (Terry and Segall 1947, Terry 1950, Akesson 1959b, Bayani-Sioson 1964, Schelling, Tetreault, Lasagna et al 1965, Rao and Sisodia 1970, Ali, Azad Khan, Mahtab et al 1994, dental caries (Chung, Witkop and Henry 1962), eye disease (Becker and Morton 1964, Suzuki, Takeuchi and Kitazawa 1966, Alsbirk and Alsbirk 1972, Kalmus and Lewkonia 1973, thyroid disorders (Harris, Kallmus and Trotter 1949, Kitchin, Howel-Evans, Clarke et al 1959, Shepard and Gartler 1960, Fraser 1961, Shepard 1961, Brand 1963, Hollingsworth 1963, Bayani-Sioson 1964, Azevedo, Krieger, Mi et al 1965a, Covarrubias, Barzelatto, Stevenson et al 1965, De Luca and Cramarossa 1965, Paolucci, Ferro-Luzzi, Modiano et al 1971, Mendez de Araujo, Salzano and Wolff 1972, Persson, Kolendorf and Kolendorf 1972, Facchini, Abbati and Campagnoni 1990, Haque 1990, Koertvelyessy and Crawford 1990, Facchini, Pettener, Rimondi et al 1997, schizophrenia (Freire-Maia, Karam, Mehl et al 1968, Schlosberg andBaruch 1992), gastrointestinal ulcers (Kaplan, Fischer, Glanville et al 1964, Stanchev, Tsonev and Minchev 1985, Li, McIntosh, Byth et al 1990), depression …”

Section: Ptc Taster Status and Diseasesmentioning

confidence: 99%

The genetics of phenylthiocarbamide perception

Guo

Reed

2001

Annals of Human Biology

262

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The ability to taste the bitter compound phenylthiocarbamide (PTC) and related chemicals is bimodal, and all human populations tested to date contain some people who can and some people who cannot taste PTC. Why this trait has been maintained in the population is uncertain but this polymorphism may influence food selection, nutritional status or thyroid metabolism. The gene product that gives rise to this phenotype is unknown, and its characterization would provide insight into the mechanism of bitter taste perception. Although this trait is often considered a simple Mendelian trait, i.e. one gene two alleles, a recent linkage study found a major locus on chromosome 5p15 and evidence for an additional locus on chromosome 7. The development of methods to identify these genes will provide a good stepping-stone between single-gene disorders and polygenic traits.

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Section: Ptc Taster Status and Diseasesmentioning

confidence: 99%

The genetics of phenylthiocarbamide perception

Guo

Reed

2001

Annals of Human Biology

262

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Zuckerkonsum bei Patienten mit Morbus Crohn

Miller¹,

Fervers²,

Rohbeck³

et al. 1976

Verhandlungen Der Deutschen Gesellschaft Für Innere Medizin

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Funktionspr�fungen und St�rungen des Geschmackssinnes

Rollin

1975

Arch Otorhinolaryngol

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In a first anatomical section the peripheral gustatory pathways, their central connections, nuclei and cortical projections are discussed. It is evident, that the gustatory fibres from the posterior part of the tongue run in the IX nerve and those from the soft palate reach the medulla oblongata via the petrosal and facial nerve. For the anterior part of the tongue there obviously exists only one gustatory pathway via the chorda tympani-facial nerve. About the further central pathways of taste fibres is much less known. In a second part the methods of taste testing with different taste solutions and the electrogustometry are described. Their practical use and the pitfalls of testing are considered. The disorders of the taste sense compose a third part. Genetic and endocrine abnormalities as well as the side effects of drugs and radiotherapy and the destruction of taste nerves may lead to gustatory deviations. The possibility of central gustatory disorders, especially the combined loss of taste and smell as a result of trauma are mentioned. A chapter dealing with the therapy of taste disorders and a short outlook on the genetic aspects of this oral sense complete this review.

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Differential Taste Sensitivities in Duodenal and Gastric Ulcer Patients

Cited by 21 publications

References 13 publications

The genetics of phenylthiocarbamide perception

The genetics of phenylthiocarbamide perception

Zuckerkonsum bei Patienten mit Morbus Crohn

Funktionspr�fungen und St�rungen des Geschmackssinnes

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