Differential Symptom Reduction by Drugs and Psychotherapy in Acute Depression

Sequence of improvement in depressive symptoms across cognitive therapy and pharmacotherapy

“…The outcomes of this study are consistent with past research that found vegetative and cognitive symptoms changed in unison in response to PT (Rush et al, 1981) or to a psychosocial treatment (DiMascio et al, 1979). However, our findings are also discrepant from research showing that different patterns of improvement are evident in such symptoms in response to PT (DiMascio et al, 1979;Haskell et al, 1975) or CT (Rush et al, 1981).…”

Remission in Major Depressive Disorder: A Comparison of Pharmacotherapy, Psychotherapy, and Control Conditions

“…Published articles by the same research group that focused on the same study group were pooled to ensure the independence of studies included in our review. Our inclusion criteria were met by six main articles (21)(22)(23)(24)(25)(26) presenting efficacy data and seven companion articles (27)(28)(29)(30)(31)(32)(33) with additional relevant data.…”

State of the Science on Psychosocial Interventions for Ethnic Minorities

“…There is no evidence that one is differentially effective, and both have some relapse-prevention effects (Elkin et al 1989. Six major studies have found CBT comparable in efficacy to pharmacotherapy (Blackburn et al 1981, DiMascio et al 1979, Hersen et al 1984, Hollon et al 1992, Murphy et al 1984, Rush et al 1977; none of the studies included analyzable subsamples of ethnic minorities. Finally, in the National Institute of Mental Health Treatment of Depression Collaborative Research Project (Elkin et al 1989), an extremely important study documenting the effectiveness of CBT and IPT as compared with medications, only 11% of the participants were ethnic minorities, and there was no power to examine ethnic responses to care.…”